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- These neutralizing antibodies ( would immunize the body against HI oer a person's lifetime. 这些抑制性的抗体将终生保护机体免受艾滋病毒的攻击。
- E2 protein, including hypervariable region 1 (HVR1) in the N-terminal region, contains some epitopes that can induce neutralizing antibodies. 包括高变区的E2蛋白含有中和性抗原表位,能诱导机体产生中和性抗体。
- Neutralizing antibodies and peptide-receptor antagonists have both been shown to be effective antagonists in vivo. 中和抗体和肽受体的拮抗剂都在在体实验中显示出有效的拮抗作用。
- Conclusion Recombinant S1 protein showed solid antigenicity.These results laid a foundation for the research of vaccine and neutralizing antibodies. 结论重组表达的S1蛋白具有较强的抗原性,为进一步的疫苗研究和抗体筛选奠定了基础。
- This was confirmed with neutralizing antibodies against FGF-2 and VEGF, which decreased the angiogenic effects of these soluble factors. 用FGF-2 和VEGF的中和抗体可降低这些可溶性因子促进血管形成的效应。
- In 12 patients, the neutralizing antibodies recognized only a conformational epitope requiring proper folding of the epoetin protein. 在所有的患者中。
- In particular, position 98 might be involved in neutralizing antibodies, modulating the virus-receptor interaction and enhancing the virulence of the viruses. 特别地,位点98可能与中和抗体、调节病毒与受体的相互作用以及增加病毒的毒力相关。
- Moreover, the glyeoprotem is a critical target of antiviral neutralizing antibodies and is important in the development of vaccine immuno-gens and antiviral treatment. 它是病毒中和性抗体的靶点,在疫苗研究和抗病毒治疗研究中均占有重要地位。
- From their search, the authors identified 10 neutralizing antibodies with activity against all of the group 1 viruses tested, including H5N1 as well as H1N1 (Spanish flu). 通过寻找,作者针对第1组被测病毒确定了10种有活力的中和抗体,这一组包括H5N1及H1N1(西班牙流感)。
- A poisonous substance, especially a protein, that is produced by living cells or organisms and is capable of causing disease when introduced into the body tissues but is often also capable of inducing neutralizing antibodies or antitoxins. 毒素一种有毒物质,尤指蛋白质,由活着的细胞或生物体产生,当进入身体组织后能够导致疾病,但通常也可导致生成中性抗体或抗毒素
- The results provide evidence that broadly neutralizing antibodies to HCV protect against heterologous viral infection and suggest that a prophylactic vaccine against HCV may be achievable. 这个结果提示我们HCV广泛中和抗体对不同准种感染均具有保作用,制作HCV保护性疫苗是可行。
- Until now, four broadly neutralizing antibodies had been isolated from HIV-positive patients in the Americas, Europe and Australia. But scientists have struggled to design a vaccine around them. 到目前为止,已经从美洲、欧洲和澳大利亚的HIV阳性患者体内分离出了四种具有广泛中和性的抗体。不过科学家们仍努力在抗体的基础上设计出疫苗。
- Precisely identify the target of neutralizing antibodies to face such a situation, as if caught in the vast ocean of people's war, thus also received HIV immune escape capabilities. 精确识别目标的中和抗体面对这种情况,仿佛陷入了人民战争的汪洋大海,由此HIV也获得了免疫逃逸的能力。
- In all patients, neutralizing antibody titer slowly decreased when epoetin treatment was discontinued. 当治疗被终止后,抑制性抗体的浓度也逐渐下降。
- Infected by Hantaan type and Seoul type viruses of HFRS. in apparent infected population,IgG and neutralizing antibody decreased with time. 肾综合征出血热(HFRS)汉滩(Hantaan)型和汉城(Seoul)型病毒在感染人体后,显性感染人群IgG抗体、中和抗体随着时间的推移,逐年下降。
- BCG-CpG-DNA increased the anti-HBs neutralizing antibody level,promoted the production of antigen specific IgG2a,induced Th1 immune response,and partially reversed Th2 response. BCG-CpG-DNA能提高抗-HBs中和抗体水平,促进抗原特异性IgG2a的产生,诱导Th1型免疫应答,与铝佐剂协同作用能部分逆转Th2反应。
- Conclusion The clinical trials indicated that the purified rabies vaccine prepared from Vero cells only showed slight side reaction and had good neutralizing antibody response. 该疫苗经临床观察和中和抗体测定的结果显示,副反应轻微,且有良好的中和抗体应答。
- I am doing an experiment of neutralizing acid. 我在做一个中和酸的实验。
- He has a rather neutral character. 他品性平平。
- The epitope inducing neutralizing antibody in high variable region 1 (HVR1) is the reason for escape of host immune surveillance, evolution of chronic infection, and also difficulty of producing wide spectrum vaccine. 由于诱导中和抗体的抗原表位恰好位于其包膜抗原E2蛋白的高变区 1(HVR1) ,因而容易逃避机体的免疫监视 ,形成慢性感染 ,同时造成发展广谱预防性疫苗的困难。