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- neuronal NO synthase 海马
- Kapinya KJ,Lowl D,Futterer C,et al.Tolerance against ischemic neuronal injury can be induced by volatile anesthetics and is inducible NO synthase dependent[J].Stroke,2002,33(7):1889. 李继庆;张联峰;王洋松;等.;异氟醚预处理对大鼠全脑缺血再灌注损伤的保护作用[J]
- Nitric oxide can be produced in plant cells via animal NO synthase (NOS) or nitrate reductases and through nonenzymatic reactions. 摘要植物体可以通过依赖于类似哺乳动物的一氧化氮合成酶或硝酸还原酶的酶促合成途径和非酶促合成途径产生一氧化氮。
- Objective To confirm a neurotoxic role for neuronal NO during ischemia and anoxia. 目的为进一步证实缺血、缺氧时神经原性NO的神经毒性作用。
- There are decrease of ATP content,increase of LDH leakage,No production and NO Synthase(NOS)activity were obviously elevated during H/R. 缺氧/复氧损伤引起大鼠脊髓组织ATP含量减少和LDH漏出增多,NO生成和NOS活性明显增加。
- NG-methyl-L-arginine (L-NMMA), the inhibitor of NO synthase, inhibited the production of NO and reversed the decrease of ATP and KBR. 一氧化氮合酶抑制剂NG-甲基-L-精氨酸(L-NMMA)可以抑制NO产生, 并使降低的肝细胞ATP含量和KBR得以恢复。
- Nitric Oxide(NO) mediate a number of physiological functions in hepatocytes,and the pathological processes of viral hepatitis NO synthase(NOS). 一氧化氮(NO)参与肝细胞的多项生理功能调节,参与病毒性肝炎的病理过程。
- Objective: The effects of nitr ic oxide(NO)and NO synthase inhibitor on endotoxin(ETX)-in- duced CGRP release from rat spinal cord in vitro were studied. 目的:探讨一氧化氮(NO)及NO合成酶(NOS)抑制剂对内毒素引起的大鼠脊髓降钙素基因相关肽(CGRP)释放的影响。
- Aminoguanidine (AMG), a specific inducible NO synthase inhibitor (100 M, 1 mM), inhibited the effect of LPS, while 10M AMG did not inhibit the effect of LPS. iNOS特异性抑制剂AMG孵育LPs处理过的主动脉环1小时,对主动脉低反应的抑制作用呈浓度依赖性,roo林M和lmM的AMG能完全取消LPS引起的主动脉环的低反应性,10“M的AMG则没有这个效果。
- NO donor L Arg and ET receptor antagonist TAK 044 could alleviate the hepatic I/R injury in some degree, whereas NO synthase inhibitor L NAME aggravated the damage. NO供体L 精氨酸 (L Arg)与ET受体拮抗剂TAK 0 44在一定程度上可减轻肝I/R损伤 ,而NO合酶抑制剂L NAME进一步加重了损伤。
- Observed the effects of mRNA transcriptional inhibitor Actinomycin D, protein synthesis inhibitor Actidione and NO synthase(NOS) inhibitor N-monomethyl-L-arginine(L-NMMA) on the activity of iNOS and intracellular GSH in mouse peritoneal macrophages. 2观察 m RNA转录抑制剂、蛋白质合成抑制剂和 NOS抑制剂对巨噬细胞 i NOS活性和细胞内 GSH水平的影响 ;
- To study the mechanism of the dysfunction of platelet after coronary artery stent implantation (CASI),we observed the change of the product of nitric oxide (NO),activity of NO synthase (NOS) and L-Arginine transport before and after CASI. 通过观察冠心病人PTCA支架植入术后血小板一氧化氮(NO)生成、NO合酶(NOS)活性和L-精氨酸(L-Arg)转运的变化,探讨PTCA支架术后血小板功能受损的机制。
- NO synthase inhibitor:NG-Nitro-L- arginine(L-NNA),NG-nitro-L-arginine methyl ester (L-NAME),NG-monomethyl-I-arginine acetate(L-NMMA),7-Nitroindazole had no effects on basel and the ETX-induced CGRP release from spinal cord in uitro. 各种NOS抑制剂L-NNA,L-NAME,L-NMMA和7-NI对离体大鼠脊髓CGRP的基础释放以及内毒素引起的CGRP释放均无明显影响。
- The role of DDAH is to break down modified amino acids (Asymmetric dimethylarginine (ADMA) and monomethyl arginine (L-NMMA)) that are produced by the body and hae been shown to inhibit NO synthase. DDAH的作用是破坏由体内产生的被修饰的氨基酸(不对称的二甲基精氨酸(ADMA)和一甲基精氨酸(L-NMMA))并已证实它可以抑制NO的合成。
- Such phosphorylation results in endothelial NO synthase activation, which provides a novel explanation for the pleiotropic effects of statins that benefit the cardiovascular system. 如此磷酸化导致内皮NO合酶激活,为他汀类药物有益心血管系统的多效性提供了一个新的解释。
- Whether it rains or not makes no difference to me. 下不下雨对我来说都一样。
- The cruel landlord would bate him no rent. 那个狠心的地主不肯给他减租。
- No horse has a speed comparable to that of his. 没有一匹马的速度能比得上他的马。
- A transistorize radio takes no time to warm up. 晶体管收音机不需要预热时间。
- In no minute did the sea run amuck. 倾刻间海上刮起了大风暴。