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- AIM: To study the effect of ischemic postconditioning on myocyte apoptosis in rats with myocardial ischemia reperfusion (MIR). 目的:观察缺血后处理对大鼠缺血再灌注心肌细胞凋亡的影响。
- Methods: Using HE staining and TdTmediated dUTP nick endlabeling (TUNEL) to detect cardiac myocyte apoptosis in spontaneously hypertensive rats. 方法:运用HE染色及TdT介导的dUTP缺口末端标记法(TUNEL)检测自发性高血压大鼠心肌细胞凋亡。
- Then we observe the change of myocardium enzymatic dynamics and detect myocyte apoptosis with electronic microscope and situ end labeling way. 观察各组家兔血清心肌酶学变化,并通过电镜形态学及原位末端标记法检测心肌细胞凋亡情况。
- Application of SOD and /or Hypoxia-preconditioning can prevent myocardiac injury partly by reducing the myocyte apoptosis. SOD和或缺氧预处理具有抗心肌细胞损伤和减轻心肌细胞凋亡的作用,而且可能是通过降低细胞内钙离子浓度而起作用的。
- Intervention in cardiac myocyte apoptosis may represent a new pathway for prevention and treatment of congestive heart failure. 针对凋亡发生的各个环节的各种防治方法将是今后一段时间内心力衰竭防治的新途径。
- Objective: To explore the effect of breviscapine(BRE) on cardiac myocyte apoptosis and on the expression of bcl-2 during myocardial ischemia/reperfusion course in rats. 目的 :探讨灯盏花素 (breviscapine,BRE)对大鼠缺血 -再灌注 (ischemia/reperfusion ,I/R)心肌细胞凋亡和凋亡抑制基因bcl 2表达的影响。
- Myocyte apoptosis may play a pivotal role in MI,the suppression of Bcl-2 and the over expression of Bax,P53,Fas induce signal pathways of cardiomyocyte apoptosis, ACEI inhibits the cardiomyocyte apoptosis by effects of these genes. 大鼠急性心肌梗死后心肌细胞存在凋亡现象,Bcl-2表达下降,Bax、P53、Fas表达上调介导心肌梗死后心肌细胞凋亡的发生。 ACEI可通过干预上述基因抑制急性心肌梗死后的心肌细胞凋亡。
- Aim:To discuss the effects of restrained stress on cardiac myocyte apoptosis of rats in the whole body,and the effect of anti-stress-induced cardiac myocyte injury treated by Chinese herbs Yixinning. 目的:探讨束缚应激对大鼠心肌细胞凋亡的影响及中药颐心宁抗应激性心肌损伤的作用。
- Objective To observe mainly the effect of the Chinese traditional medicine (compound Wenxin soup) on myocyte apoptosis and path-histology change in rabbits ischemia referpusion injury. 目的观察中药复方温心汤对家兔心肌缺血再灌注损伤心肌细胞凋亡以及病理组织学改变的影响。
- Keywords stress;cardiac myocyte apoptosis;"Yixinning"Chinese herbs; 应激;心肌细胞凋亡;中药颐心宁;
- Myocyte apoptosis in chronic compressive injury of spinal cord and decompression in rats 鼠慢性脊髓压迫及减压后骨骼肌细胞的凋亡
- Protective Effects of Oxymatrine on Myocyte Apoptosis in Rats with Acute Myocardial Ischaemia 氧化苦参碱对大鼠急性心肌缺血时心肌细胞凋亡的影响
- Keywords myocyte apoptosis;ischemia preadaptation;Wenxin soup;electronic microscope; 关键词细胞凋亡;预适应;温心汤;电镜;
- Changes of cardiac myocyte apoptosis and effects of Carvedilol during heart failure subsequent to myocardial infarction in rats 心衰大鼠心肌细胞凋亡的变化及卡维地洛对其干预的作用
- Myocyte apoptosis and expression of Bcl-2 and Bax in the patients with coronary disease complicated with sudden death and its clinical significance 冠心病猝死者心肌细胞凋亡与Bcl-2和Bax基因蛋白表达及其临床意义
- Study of a Combination Therapy with Enalapril and Losartan in Modification of Myocyte Apoptosis in Spontaneous Hypertensive Rats 依那普利、络沙坦合用对自发性高血压病鼠心肌细胞凋亡影响的研究
- Effect of Wenxin Capsule on Myocyte Apoptosis and Expression of Bcl-2, Fas Gene Protein in Rats of Experimental Myocardial Ischemia 温心胶囊对大鼠实验性缺血心肌细胞凋亡及Bcl-2、Fas蛋白表达的影响
- LVEDD was highly correlated to MND(r=-0.793, P<0.01)and to myocyte apoptosis rate(MAR_1,r=0.842, P<0.01;MAR_2,r=0.771, P<0.01); L VEDD分别与心肌细胞核密度及凋亡率高度相关 ( MND;r=- 0 .;793;P<0
- Effects of allograft bone marrow mononuclear cell implantation on rat cardiac myocyte apoptosis and expression of apoptosis-associated genes after acute myocardial infarction 同种异体骨髓单个核细胞移植对急性心肌梗死后大鼠心肌细胞凋亡及相关基因表达的影响
- In vitro effects of flavone from leaves of Diospyros kaki on rat cardiac myocyte apoptosis in-duced by hypoxia-reoxygenation and advanced glycation end products 柿叶黄酮对缺氧复氧以及晚期糖基化终产物诱导的乳鼠心肌细胞凋亡的影响