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- In addition, development of drugs targeting at the maintenance of endothelial gap junction may benefit patients with atherosclerotic disease. 而且,稳定缝隙连接的药物的发展可以给动脉粥样硬化疾病的患者带来福音。
- These results indicate that endothelial gap junctions are highly involved in atherogenesis and suggest that down-regulation of endothelial gap junction may be used as a marker of endothelial dysfunction. 这些结果说明内皮缝隙连接与动脉粥样硬化的发生高度相关,提示我们可以把内皮缝隙连接下调作为内皮功能障碍的一个标志。
- Aim To explore the role of endothelial gap junctions in intercellular communication and vascular endothelial wound repair. 摘要目的探讨内皮缝隙连接在介导细胞间通讯及在损伤血管内皮修复中的作用。
- In vascular endothelium gap junctions contain up to 3 types of connexins that is connexin37 (Cx37), Cx40, and Cx43. 在血管内皮中,缝隙连接包括至少三种连接素,即连接素37(Cx37)、Cx40和Cx43。
- To understand the role of endothelial gap junctions in the process of atherosclerosis we have been investigating the impact of atherogenic factors on the expression of endothelial connexins using animal models and cell culture systems. 为了更好的理解内皮缝隙连接在动脉粥样硬化症中的作用,我们已经在动物模型和体外细胞培养实验中研究了导致动脉粥样硬化的因素对内皮连接素表达的影响。
- AIM:To investigate the express of the gap junction protein connexin43(Cx43)in the BN rat retina. 目的:探讨细胞间隙连接蛋白connexin43(Cx43)在BN大鼠视网膜中的分布特点。
- The function of gap junction intercellular communication(GJIC) of HTFs cells was detected by scrape-loading lucifer yellow dye transfer method. 染料传输法观察HTFs细胞间隙连接细胞间通讯(G JIC)的能力;
- The gap junction intercellular communication can be used to improve the killing of cancer cells. 肿瘤细胞的间隙连接胞间通讯可以用来提高肿瘤细胞的杀伤率。
- Gap junction remodelling may be correlated with electrical remodelling and autonomic nerve activity. 缝隙连接重构与电重构和自主神经之间可能有密切关系。
- AIM: To explore the effects of carbenoxolone (CBX), a gap junction blocker, on the neuron injury induced by focal cerebral infarct. 目的 :探讨缝隙连接阻断剂甘珀酸对大鼠光化学局灶性脑梗死神经元损害的影响 .
- Methods: Experimental rats were intrathecally injected with carbenoxolone(CBX), a special gap junction blocker, and the control rats with the saline. 方法 :向实验组大鼠鞘内注射一种缝隙连接的阻断剂甘珀酸 ;
- During 24-28 weeks,the epithelial layer increased to 4-10 layers,the cellularity was clear,with more gap junction and less intermediate junction. 24~28周时上皮增至4~10层,细胞结构清晰,细胞间连接以缝隙连接为主,较少中间连接。
- It is found that the normal conduction and abnormal conduction which induce cardiac arrhythmia are directly relatived with gap junction. 现已证实心脏的正常传导和引起心律失常的异常传导都与缝隙连接直接相关。
- Using SLDT technique to test the effect of BP on recovering the function of cell Gap junction mediated intercellular communication (GJIC). 建立不同途径的肿瘤转移模型,体内观察罗勒多糖对肿瘤转移行为的影响。
- The electronical coupling of excitable cell is implement by specific intercellular structure which is called gap junction. 可兴奋细胞间的电耦联是通过一种特殊的胞间结构来实现的,这种结构即是缝隙连接。
- Objective: To explore the effects of Fufang Tengligen Mixture on growth and gap junction intercellular communication(GJIC) of PG cell line. 目的:探讨复方藤梨根制剂对高转移性人肺癌细胞(PG)的生长及细胞间隙连接通讯功能的影响。
- Gap junctions serve as pathways of intercellular communication. 间隙连接是细胞间交流的途径。
- Myocardial gap junction plays an important role in cell to cell conduction of electrical and chemical signals in myocardium. 心肌缝隙连接是心肌细胞之间的连接通道,在维持细胞正常电、化学信号传递中起着重要作用。
- The recent research results on the mechanism of carotenoid such as anti-oxidation, intensify immunology, gap junction are described. 本文介绍近年来对类胡萝卜素作用机理的最新研究成果,即抗氧化作用、缝间联接作用、免疫增强作用。
- Such general characteristics of the endothelial cells with proliferating macrocapillarles as gap junctions and thinness or absence of the basement membrane suggested that they be very fragile and susceptible to bleeding. 这些增殖性巨大微血管内皮细胞的裂隙结合处比较大,且有些部份的基底膜变薄甚至缺损,这些特徵表示血肿外膜较脆弱较容易出血。