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- muscarinic ncurotransmission 毒蕈碱性神经传递
- Rat muscarinic acetylcholine receptor... 大鼠毒蕈碱型乙酰胆碱受体(M-AChR)ELISA Kit；
- Specific binding is found in tissues where muscarinic receptors are demonstrable pharmacologically. 在药理学方法证明有毒蕈碱样受体的组织中发现了特异的结合作用。
- Blocks agonist or antagonist activity at adenosine, adrenergic, dopaminergic, muscarinic, opioid and P2Y receptors. 阻碍腺苷酸、肾上腺素、毒蕈碱、类鸦片活性肽和P2Y的受体的拮抗剂或对抗剂活性。
- The modulatory effect of Ach on the IATP may be achieved by activating muscarinic receptor (M receptor). 乙酰胆碱对I(下标ATP)的调制作用是通过毒蕈碱样乙酰胆碱受体（M受体）激活实现的。
- AIM To examine whether the endo-thelial-target for acetylcholine is different from muscarinic receptors. 目的研究内皮细胞乙酰胆碱靶标与M受体药理学特征的差异。
- M5 muscarinic receptor may be a useful pharmacological target for the treatment of heroin addiction. M5毒蕈碱受体可作为改变海洛因行为学效应的有效药理学靶点之一.
- Aim To clone the muscarinic receptors M1, M3 and M5 sequences of astrocyte cells,and compare the gene and protein sequences with those of neurons. 目的克隆胶质细胞M1、M3、M5受体亚型基因序列,比较胶质细胞和神经细胞M1、M3、M5受体亚型基因序列、蛋白质序列的差异。
- Pirenzenpine is a relatively selective M1 subtype muscarinic receptor antagonist and used to treat digestive system ulcer. 哌仑西平是一种M1受体选择性的抗胆碱药,临床上用于治疗消化性溃疡。
- Darifenacin is a selective muscarinic M3-receptor antagonist that has been used in patients with overactive bladder syndrome (OAB). 达非那新是一种选择性M3受体阻滞剂,临床主要用于治疗膀胱过度活动综合征。
- We proved the existence of muscarinic receptors and vagal nerves innervation in ventricle with histochemical staining and molecular biological methods. 通过组织化学染色及分子生物学方法进一步证明心室有毒蕈碱受体分布；
- The gene expression of muscarinic receptors, including M1 and M2, was significantly lower at 90mg/kg group than that in control group (P<0.01). 90 mg/kg组大鼠心肌M1及M2受体的mRNA表达均显著低于对照组（P<0.;01）。
- At the end of observation, the activity of AChE and ATPase and the gene expression of muscarinic receptor, M1 and M2 in cardiac muscle were measured. 同时测定心脏AChE活力、ATPase活力和M1、M2受体基因表达水平。
- Nilvebrant L, Hallen B, Larsson G.Tolterodine, a new bladder selective muscarinic receptor antagonist: Preclinical pharmacological and clinical data[J].Life Sci,1997,60:1129. 吴士良;杨勇;薛兆英;等.;新型抗胆碱能药物托特罗定治疗膀胱过度活动症的临床研究[J]
- Muscarinic M1 receptor has close relation to AD since the activation of M1 receptor can inhibit the formation of amyloid spot and improve the function of cholinergic system. 毒蕈胆碱M1受体和阿尔茨海默病有着密切的联系，其激活能有效的改善胆碱能系统活性和抑制脑内淀粉斑的形成，是治疗和减缓该病的有效途径。
- The effect of a general anaesthetic (halothane) on the muscarinic K+ channel (iK,ACh) in guinea-pig atrial cells was investigated using the whole-cell patch clamp technique. 本实验采用全细胞膜片箝方法, 观察了麻醉药氟烷对豚鼠心房肌细胞iK, ACh的影响。
- In contrast, microinjection of M5 muscarinic receptor sense oligonucleotide (S-ONs) into the VTA did not block the expression of behavioral sensitization or the expression of FosB in the NAc or DG in the heroin sensitized rats. 但VTA中注射有义寡核苷酸(M5S-ONs)不能明显抑制大鼠行为敏化的表达,也不能抑制海洛因敏化大鼠NAc和DG中FosB蛋白的表达。
- The enhancement of FosB-positive neurons in the NAc or DG could be inhibited by microinjection of M5 muscarinic receptor AS-ONs into the VTA before the heroin-induced locomotor sensitization was performed. 海洛因诱导的行为敏化大鼠中NAc及DG中的FosB免疫反应阳性神经元的表达增加,而在VTA内注射M5AS-ONs能明显抑制NAc及DG中FosB阳性神经元表达的增加;
- To generate M2AChR-Gila fusion protein in baculovirus-Sf9 cells system and detect the effects of various muscarinic ligands and magnesium ion on the interaction of fused M2AChR and Gila. 目的:表达M_2AChR-G_(ila)融合蛋白;检测不同配体或镁离子对M_2AChR与G_(ila)间相互作用的影响.
- Aim: To establish the chick model of form deprivation myopia (FDM) and observe whether the muscarinic anagonist atropine can effectively reduce or prevent FDM and study its pathway in intraocular. 摘要目的：建立形觉剥夺性近视模型，观察阿托品能否抑制近视的发生并进一步研究阿托品抑制近视发生的作用机制。
