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- As yet, there is no national data about human rotavirus antigen gene expressed in transgenic plants although there are reports of murine (epitope of NSP4) or bovine (VP6) rotavirus (Matsumura et al., 2002; Yu J et al., 2001). Wang等人1999年将猪源轮状病毒VP7基因改造后在大肠杆菌中表达，也具有很好的中和病毒能力，何金生等人2001年以腺病毒表达人源轮状病毒VP7免疫小鼠，产生较强的体液和粘膜免疫应答，次年彭世勇等人用pCI分别进行VP7、VP4和VP6基因的DNA疫苗研究，结果仅VP7诱导最强的免疫应答。
- It is a new approach to study and produce HCV vaccine by using multi-epitope antigen of HCV. In this study, multi-epitope antigen gene, PCX, which consists of 5 epitopes of HCV and an epitope of T cell stimulation o f tetanus toxoid, was expressed in E. 利用HCV抗原多表位来研制HCV疫苗是目前的一个新方向。
- Objective Cloning of 14-3-3 antigen gene of Schistosoma japonicum in order to its study for immunological diagnosis and prevention. 目的克隆日本血吸虫14-3-3抗原的编码基因,以研究其用于血吸虫病免疫诊断和免疫预防效果。
- The combined PCX/S antigen gene could induce specific immune response and it might be able to serve as a bivalent DNA vaccines candidate specific for HCV and HBV. 复合型PCX/S抗原基因可诱发特异性免疫应答,为HCV/HBV双价疫苗的研究提供一定实验基础。
- Methods The specific PCR primers were designed and synthesized to amplify the DNA fragments enconding preS1/S2/S antigen gene from the plasmid pHBV adr by PCR method. 方法设计合成2对寡核苷酸引物,以adr亚型HBV质粒pHBV DNA为模板,采用PCR法分别扩增HBV大分子表面蛋白基因(preS1/S2/S基因)片段;
- E. granulosus ferritin gene gained from protoscolexes can be used as candidate antigen gene to develop vaccine and further biological functions studying. 结论 测序的铁蛋白基因序列有完整的编码框，为进一步研究其结构和功能，以及对包虫病的免疫预防具有重要意义。
- Conclusion The full length variant-specific surface antigen gene from the isolate of G. lamblia has the common characteristics with other previously identified VSPs. 结论 中国人源蓝氏贾第鞭毛虫滋养体表达的表面变异抗原基因具有与已鉴定的蓝氏贾第鞭毛虫表面变异抗原基因同样的特性。
- multi epitope gene 多表位基因
- Unlike AIDSVAX, ALVAC is made of highly engineered viruses into which the antigenic genes have been incorporated. 与AIDSVAX不同，ALVAC是由高度基因工程制造的病毒组成，抗原基因被并入这些病毒。
- In this paper, the research in optimization design for DNA vaccine was reviewed, including choice of antigen gene and immune adjuvant, optimization of plasmid vectors and inoculation methods. 许多试图增强和调节质粒DNA疫苗的免疫原性和效率的方案都在研究之中。
- Keywords SARS - CoV;spike protein;epitope;chimeric antigen gene;genetic engineering vaccine; 关键词SARS冠状病毒;S蛋白;抗原表位;嵌合抗原基因;基因工程疫苗;
- Multiepitope antigenic gene (MAG) 多表位抗原基因
- Carcinoembryonic Antigen Gene Family and Cancer 癌胚抗原基因家族与肿瘤
- epitopes antigen of hepatitis a virus HAV表位抗原
- [viral] group-specific antigen gene [病毒]类特异抗原基因
- [viral]group-specific antigen gene [病毒]类特异抗原基因
- hepatitis B surface antigen gene (HBsAg gene) 乙肝表面抗原基因
- Turn the mode dial to select multi exposure mode. 把模式盘转到多重曝光模式。
- hepatitis B virus surface antigen gene 乙肝病毒表面抗原基因
