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- Objective To obtain the optimal prescription of Mosapride Citrate Tablets(MCT) to improve the tablets dissolution. 目的筛选枸橼酸莫沙必利片的最佳工艺处方,提高溶出度。
- Methods To improve the dissolution rate of Mosapride Citrate(MC)by whetting with lactose. 方法采用枸橼酸莫沙必利与乳糖研磨的方法提高其溶出速率。
- Objective: To observe the curative effect in patients with diabetic gastroparalysis (DGP) treated with mosapride citrate tablet. 目的 :观察新型消化道动力药枸橼酸莫沙必利片治疗糖尿病胃轻瘫 (DGP)的疗效。
- As a new type of gastroenteric prokinetic drug, mosapride citrate tablet is more prospective than domperidone and cisapride to treat DGP. 枸橼酸莫沙必利片是一种比吗丁啉片、西沙必利片更有前途的治疗 DGP的新型促消化道动力药
- Results The dissolution of Mosapride Citrate is better than that of original Mosapride Citrate Tablets according to the quality standard. 结果以优选处方工艺制备的产品溶出度均大大提高,符合质量标准。
- Methods: 116 cases of DGP were randomly divided into three groups. 48 cases were treated with mosapride citrate tablet and the remaining in the other two groups were treated with domperidone or cisapride respectively. 方法 :116例确诊为DGP患者随机分为 3组 ,采用枸橼酸莫沙必利片治疗 4 8例 ,并与吗丁啉片、西沙必利片治疗者进行比较。
- Mosapride citrate dispersible tablets 莫沙必利分散片
- Keywords cor pulmonale;digestive tract symptom;mosapride citrate; 肺心病;消化道症状;枸椽酸莫沙必利;
- Keywords mosapride citrate;5 HT4 receptors excitant;synthesis; 枸橼酸莫沙必利;5-HT4受体激动剂;合成;
- Keywords Mosapride citrate;determination;RP-HPLC;orally disintegrating tablets; 枸橼酸莫沙必利;含量测定;反相高效液相色谱法;口崩片;
- Keywords mosapride citrate;relative bioavailability;pharmacokinetics;RP-HPLC; 莫沙必利;生物利用度;药动学;反相高效液相色谱法;
- Keywords mosapride citrate;ion pair RP HPLC;internal standard;determination; 枸橼酸莫沙必利;反相离子对HPLC;内标;测定;
- The clinic observing of mosapride citrate in treatment of cor pulmonale combination digestive tract symptom 枸椽酸莫沙必利治疗肺心病并消化道症状临床观察
- Keywords Gastric emptying rate;Gastric movement;Jianpi Xiaozhang Supplement;Mosapride Citrate; 胃排空率;胃运动;健脾消胀制剂;枸橼酸莫沙必利;
- Keywords Compound azintamide;Mosapride citrate dispersible tablets;Functional dyspepsia;Drug therapy; 复方阿嗪米特;莫沙必利分散片;功能性消化不良;药物治疗;
- Keywords Mosapride Citrate;Dispersible Tablets;Receptors;Serotonin;5-HT4;Guinea Pigs;Gastric Emptying; 关键词枸橼酸莫沙必利;分散片;受体;血清素;5-HT4;豚鼠;胃排空;
- [11]Zhao XH,Hu JG,Bai DL.The clinical study of mosapride citrate for functional dyspepsia.Journal of Ningxia Medical College,2003; 赵晓红;胡建国;白东莉.;枸橼酸莫沙必利治疗功能性消化不良的临床观察
- [16]Li ZS,Zou DW,Xu GM,et al.Effect of mosapride citrate on functional dyspepsia.Academic Journal of Second Military Medical University,2002; 李兆申;邹多武;许国铭;等.;枸橼酸莫沙必利片治疗功能性消化不良的临床研究
- Keywords chlorzoxazone;mosapride citrate;wastewater form pharmaceutical synthesis;catalytic oxidation;biochemistry;treatment engineering; 氯唑沙宗;枸橼酸莫沙必利;药物合成废水;催化氧化;生物化学;处理工程;
