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- Mammalian Mitochondrial DNA(mtDNA) control region consists of central domain, ETAS domain and CSB domain. 哺乳动物线粒体DNA(mitochondrialDNA,mtDNA)控制区由中央保守区、ETAS区和CSB区构成。
- Objective:To understand large scale deletion mutation in mitochondrial DNA(mtDNA) and its significance. 目的:了解线粒体DNA大片段缺失突变及其意义。
- Objective To simplify the DNA sequencing method and optimize the conditions for mitochondrial DNA (mtDNA) sequencing. 目的简化DNA测序方法,优化条件,以适用于线粒体DNA的测序。
- Mitochondrial DNA(mtDNA)and telomere are the primary DNA markers used in deducing individual age in recent years. 目前用于年龄推断研究的DNA标记主要是线粒体和端粒。
- Considering of the high mutative rate of the coding regions and the conservative heritance of the noncoding regions in human mitochondrial DNA (mtDNA). 针对人类mtDNA编码区突变率高和非编码区遗传保守的特点,对利用mtDNA分析人类母系血缘关系进行了初步的探索。
- Objective To detect the microsatellite instability (MSI) of mitochondrial DNA (mtDNA) in lung squamous carcinoma and to investigate its significance in carcinogenesis. 目的分析肺鳞癌患者癌组织线粒体DNA(mitochondrial DNA,mtDNA)非编码D-环区序列的微卫星不稳(mitochondrial microsatellite instability,mtMSI)现象并探讨其意义。
- The application of restriction fragment length polymophism(RFLP) of mitochondrial DNA(mtDNA) in the study of genetic diversity of domestic animals was summarized in this article. 对线粒体DNA限制性片段长度多态性(RFLP)在家养动物遗传多样性研究中的应用现状进行了综述,并对其应用前景进行了展望。
- In this article,we review the relationship between mitochondrial DNA (mtDNA) and carcinogenesis of cancer cells.The possible mechanisms are also discussed. 本综述重点讨论线粒体DNA的损伤与突变在细胞癌变中的地位和可能的作用机制。
- Mitochondrial DNA (mtDNA) is very stable, changing only gradually as it is handed down the generations, which means it is an excellent yardstick for genealogy. 粒线体DNA非常稳定,就算世代传递也只会缓慢改变,因此可以成为绝佳的血缘判断标准。
- As the only extrachromosomal DNA, mitochondrial DNA (mtDNA) has been shown to play a central role in oxidative phosphorylation (OXPHOS) and adenosine triphosphate synthesis, which decide the activities of cells. DNA 是辐射诱导增殖细胞死亡的主要靶点,线粒体DNA(mitochondrial DNA, mtDNA)作为惟一的核外遗传物质,其编码基因参与细胞氧化磷酸化(oxidative phosphorization, OXPHOS)和能量代谢,与细胞的存亡息息相关。
- In this system, cloned maize mitochondrial DNA(mtDNA) is served as template. this is the first established cell-free system for in vitro transcription of cloned DNA with a plant RNA polymerase B. 这是首次用克隆化DNA为模板,以植物RNA聚合酶B建立起的无细胞离体转录系统。
- The mitochondrial DNA (mtDNA) of piranhas has an extremely high mutation rate so this was used as a basis for reconstructing the evolution of the 28 modern species of this carnivorous fish. 水虎的线粒体DNA有极高的突变几率,这导致演化到现在有28种水虎食肉鱼存在。
- mitochondrial DNA (mtDNA) control region 线粒体控制区
- Objective To analyze mitochondrial DNA polymorphism of district of Lubunour at the Bronze Age in Xinjiang. 目的 :通过新疆罗布诺尔地区铜器时代古代居民 m t DNA多态性分析 ,探讨新疆境内古代欧洲人种成分的来源。
- Compared with the normals, the amount of the mitochondrial DNA were decreased universally in the patients with AD. (2)和正常老人相比,AD患者中线粒体DNA的数量普遍减少;
- Objective:To study the possible relationship between mitochondrial DNA point mutations and hereditary ataxia. 目的:探索线粒体DNA点突变与遗传性共济失调的关系。
- The strongest support that mitochondrial DNA offers for the African-origin hypothesis may not depend on trees. 线粒体DNA提供非洲起源说假设的最强而有力支持也许不是取决于族谱。
- Conclusion:The point mutation in this area of mitochondrial DNA might not be related hereditary ataxia. 结论:遗传性共济失调的发生、发展可能与该区域点突变无关。
- Ancient mutations in mitochondrial DNA are the same as those found in the cells of many tumors. 而在线粒体DNA中的远古突变和许多瘤细胞中发现的情况是一样的。
- From our results,mitochondrial DNA mutation may be one of major factors in aminoglycoside antibiotic induced deafness. 提示线粒体DNA点突变是导致该家系致聋的主要因素之一。