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- Genomic instability and mismatch repair mechanism 基因组不稳定性与错配修复机制
- The study about mismatch repair has been analyzed thoroughly. 在核酸配对错误复上已有相当透澈的瞭解。
- Expression of mismatch repair gene hMSH2 in human adenocarcinoma of cervix and its clinical significance. 错配修复基因hMSH2在宫颈腺癌组织中的表达
- But the large loop repair, a distinct repair from mismatch repair, is an unknown repair system. 但是大型核酸环的修复,一个迥异于配对错误的修复机制,却是个未知的系统。
- Mismatch repair gene defects are recently identified in hematopoietic malignancies, leukemia and lymphoma cell lines. 错配修复基因缺陷是最近在造血系统恶性肿瘤,白血病和淋巴瘤细胞株中被发现的。
- Conclusion A certain number of HNPCC families can be benefited from the genetic screening for mutation of the mismatch repair genes. 结论错配修复基因的突变筛选可帮助、指导临床对HNPCC家系进行严密监控。
- A team at London's Hammersmith Hospital is attempting to reverse cirrhosis of the liver by harnessing and enhancing the body's own repair mechanism. 伦敦哈默史密斯医院的一个小组尝试以控制并提高身体自己的修补机制,来反转肝的硬化。
- But if it isn’t, the DNA mismatch repair or MMR pathway targets damaged DNA bases and sets off the process of cell death via apoptosis. 但如果没有修复的话,DNA错配修复途径或MMR途径会找到损伤的DNA碱基并且通过凋亡启动细胞死亡进程。
- In recent years,deepgoing understanding of corneal endothelial cell wound about its pathology,healing process and repair mechanism has been achieved. 很多学者对角膜内皮愈合过程中各种因子的促进作用进行了系统的研究。
- The objective of this study was to define a multimarker prognostic model of 5-year survival in patients with lymph node-negative, mismatch repair (MMR)-proficient colorectal cancer (CRC). 这个研究的目的是探索淋巴结阴性的结直肠癌患者5年生存率的多标记预测模式。
- Modulation of O6-methylguanine-DNA methyltransferase(MGMT) and mismatch repair(MMR) expression in tumors and normal tissue is currently being investigated as a possible strategy ... 靶向DNA修复机制增强抗肿瘤化疗药物的疗效、克服肿瘤耐药正成为肿瘤个体化化疗研究的一个重要领域。
- Un- derstanding the biological characteristics of gastric cancer has important meaning for the diagnoses, treatment and prognosis.hMSH2 and hMLH1 are belonging to mismatch repair (MMR) gene family. 因此,了解胃癌的生物学特性对于胃癌诊断、预后评估、指导治疗有重要意义。
- This paper briefly introduces the repair mechanism of polymer alloy repair agent and concrete repairing technique. 本文简要介绍了高分子合金修补剂的修补机理及具体修补技术。
- Scientists would alter these cells by inserting genes or activating the cells'DNA - repair mechanisms. 科学家通过注入基因或激活细胞的脱氧糖核酸(DNA)修复机制来造基因。
- Objective To explore germline mutation frequencies and features of mismatch repaired gene MSH6 in persons with different kinds of colorectal cancer. 摘要目的了解错配修复基因MSH6在不同形式大肠癌人群中的种系突变频率及特征,提供真正的突变热点。
- Be able to trouble shoot and repair mechanical, electrical and hydraulic systems. 能够解决问题、修理机械、电子及水力的系统。
- Scientists would alter these cells by inserting genes or activating the cells' DNA - repair mechanisms. 科学家通过注入基因或激活细胞的脱氧糖核酸(DNA)修复机制来造基因。
- Human DNA mismatch repair gene (hMMR) 错配修复基因
- Since the human body has its own repair mechanisms, so when a serious loss of calcium, the body will involuntarily want to generate more bone cells. 由于人体有自行修复的机制,因此当钙质严重流失的时候,人体会不由自主地想要生成更多骨细胞。
- Mismatch repair is very important during replication to remove mismatches, or small insertion or deletion loops, that are generated by faulty replication. 在复制过程中,错配修复对于去除由错误复制产生的错配、插入环或缺失环是很重要的。