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- Minimal residual disease (MRD) is defined that there are residual leukemia cells in the range of 10~6-10~8 in the patients who are in complete remission (CR). 患者经治疗后,达到临床和血液学的完全缓解,体内仍有106-108个残留白血病细胞,称为微小残留病(minimal residual disease, MRD)。
- Keywords green flourescent protein;minimal residual leukemia;multi-drug resistance;DBA mice;leukemic cell;P388/VCR-G cell; 绿荧光蛋白;微小残留白血病;多药耐药;DBA小鼠;白血病细胞;P388/VCR-G细胞;
- minimal residual leukemic cell 微量残留白血病细胞
- Establishment of A Mouse Model for Detecting Multi-drug Resistant Minimal Residual Leukemia Cells Expressing Green Fluorescent Protein 表达绿荧光蛋白的多药耐药微小残留白血病细胞的小鼠模型
- Objective: To observe the effects of Fuzheng Kangbai Granule(FZKBG) on immune function and survival time in minimal residual leukemia (MRL) model mice and study its mechanism. 目的:研究扶正抗白冲剂(FZKBG)对实验小鼠免疫功能及生存期的影响,探讨FZKBG治疗微小残留白血病(MRL)的机理。
- Objective To discuss the significance of minimal residual disease detection in acute B-lymphoblastic leukemia, Surface differentiation antigen CD45- leukemic cells were detected. 目的探讨细胞表面分化抗原45阴性(CD45-)白血病细胞在急性B细胞性白血病微小残存病变监测中的意义。
- Flow Cytometric Detection of Minimal Residual Disease in Precursor-B-Acute Lymphoblastic Leukemia on the Basis of Phenotypic Aberrancies on Minor Leukemic Cell Populations 基于细胞表型异常的流式细胞术检测急性前体B细胞白血病微小残留病
- minimal residual leukemia MRL
- minimal residual leukemia(MRL) 微量残留白血病
- Conclusion Monitoring of the WT1 gene by Nest RTPCR would be a surely marker for the detection of minimal residual disease (MRD) in acute leukemia. 结论 用Nest、RT-PCR测定WT1基因的表达可作为检测白血病微小残留病(MRD)的一项指标。
- Detection of Residual Leukemic Cells after Complete Remission of Patients with Acute Myeloid Leukemia 急性髓性白血病完全缓解患者残留白血病细胞检测研究
- Objective To improve the clinical significance of detecting minimal residual disease (MRD) in acute lymphoblastic leukemia (ALL). 目的为提高急性淋巴细胞白血病(ALL)微小残留检测的临床意义。
- Objective To explore the clinical significance of quantitative analysis of minimal residual disease (MRD) cells DNA in children with acute lymphoblastic leukemia (ALL). 目的探讨定量监测儿童急性淋巴细胞白血病(ALL)微量残留病(MRD)细胞DNA变化的临床意义。
- HHV 6 DNA sequence was also present in two leukemia cell lines. 两株白血病细胞株也扩增出HHV?6DNA序列。
- More and more attention has been paid to the function of cellular immunotherapy in eradicating minimal residual disease of acute leukemia and extending the remission stage after therapy. 细胞免疫治疗在消除白血病微小残留病和延长治疗后缓解期方面的作用正日益受到人们的重视。
- INFLUENCE THE FACTORS FOR LDL?ACM COMPLEX TAKE IN LEUKEMIA CELL LINE K??562? 影响白血病细胞株 K_(562) 对 LDL-ACM 复合物摄取因素的研究
- Objective:Evaluation of methylation specific polymerase chain reaction and its potential clinical value in the detection of minimal residual disease (MRD) in adult acute leukemia with P15. 目的:评价由甲基化特异性聚合酶链反应分析P15基因甲基化对成人急性白血病微小残留病灶的检测价值。
- Objectives To investigate the possibility of predicting the outcome in children with B lineage acute lymphocytic leukemia(ALL)by monitoring minimal residual disease(MRD)in bone marrow. 目的探讨儿童B系急性淋巴细胞白血病(B-ALL)患儿骨髓微小残留病(MRD)及检测,预测预后的可能性。方法应用四色荧光抗体标记法通过流式细胞仪检测儿童B-ALL的MRD。
- Methods:APAF-1 cDNA types in leukemic cell lines K562 and CEM/VLB100 were studied by cDNA cloning strategy. 方法:应用RT-PCR结合测序方法研究白血病细胞系K562和CEM/VLB100APAF-1cDNA类型;
- RT PCR for EWS FLI 1 is sensitive enough to detect minimal residual Ewing's sarcoma cells in the bone marrow. 以EWS FLI 1融合基因为标志的反向PCR测定骨髓Ewing肉瘤细胞的灵敏度为 10 -6,它是测定骨髓Ewing肉瘤细胞高度敏感的方法 ;
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