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- Objective: To observe the effects of Fuzheng Kangbai Granule(FZKBG) on immune function and survival time in minimal residual leukemia (MRL) model mice and study its mechanism. 目的：研究扶正抗白冲剂(FZKBG)对实验小鼠免疫功能及生存期的影响，探讨FZKBG治疗微小残留白血病(MRL)的机理。
- Minimal residual disease (MRD) is defined that there are residual leukemia cells in the range of 10~6-10~8 in the patients who are in complete remission (CR). 患者经治疗后,达到临床和血液学的完全缓解,体内仍有106-108个残留白血病细胞,称为微小残留病(minimal residual disease, MRD)。
- minimal residual leukemia(MRL) 微量残留白血病
- Establishment of A Mouse Model for Detecting Multi-drug Resistant Minimal Residual Leukemia Cells Expressing Green Fluorescent Protein 表达绿荧光蛋白的多药耐药微小残留白血病细胞的小鼠模型
- minimal residual leukemia MRL
- Keywords green flourescent protein;minimal residual leukemia;multi-drug resistance;DBA mice;leukemic cell;P388/VCR-G cell; 绿荧光蛋白;微小残留白血病;多药耐药;DBA小鼠;白血病细胞;P388/VCR-G细胞;
- Conclusion Monitoring of the WT1 gene by Nest RTPCR would be a surely marker for the detection of minimal residual disease (MRD) in acute leukemia. 结论 用Nest、RT-PCR测定WT1基因的表达可作为检测白血病微小残留病(MRD)的一项指标。
- Objective To improve the clinical significance of detecting minimal residual disease (MRD) in acute lymphoblastic leukemia (ALL). 目的为提高急性淋巴细胞白血病（ALL）微小残留检测的临床意义。
- Objective To explore the clinical significance of quantitative analysis of minimal residual disease (MRD) cells DNA in children with acute lymphoblastic leukemia (ALL). 目的探讨定量监测儿童急性淋巴细胞白血病（ALL）微量残留病（MRD）细胞DNA变化的临床意义。
- More and more attention has been paid to the function of cellular immunotherapy in eradicating minimal residual disease of acute leukemia and extending the remission stage after therapy. 细胞免疫治疗在消除白血病微小残留病和延长治疗后缓解期方面的作用正日益受到人们的重视。
- Objective:Evaluation of methylation specific polymerase chain reaction and its potential clinical value in the detection of minimal residual disease (MRD) in adult acute leukemia with P15. 目的:评价由甲基化特异性聚合酶链反应分析P15基因甲基化对成人急性白血病微小残留病灶的检测价值。
- Objectives To investigate the possibility of predicting the outcome in children with B lineage acute lymphocytic leukemia(ALL)by monitoring minimal residual disease(MRD)in bone marrow. 目的探讨儿童B系急性淋巴细胞白血病(B-ALL)患儿骨髓微小残留病(MRD)及检测,预测预后的可能性。方法应用四色荧光抗体标记法通过流式细胞仪检测儿童B-ALL的MRD。
- minimal residual leukemic cell 微量残留白血病细胞
- Objective To discuss the significance of minimal residual disease detection in acute B-lymphoblastic leukemia, Surface differentiation antigen CD45- leukemic cells were detected. 目的探讨细胞表面分化抗原45阴性(CD45-)白血病细胞在急性B细胞性白血病微小残存病变监测中的意义。
- RT PCR for EWS FLI 1 is sensitive enough to detect minimal residual Ewing's sarcoma cells in the bone marrow. 以EWS FLI 1融合基因为标志的反向PCR测定骨髓Ewing肉瘤细胞的灵敏度为 10 -6,它是测定骨髓Ewing肉瘤细胞高度敏感的方法 ;
- WT1 is related to the prognosis of AML and uses as a marker in detecting the minimal residual disease. 认为WT1基因和急性髓细胞白血病(AML)的预后有关，可以作为微小残留病检测的标记；
- If, however, STI571 is shown to reduce progression to blast crisis and to obliterate all molecular evidence of residual leukemia, the role of transplantation in CML will have to be reevaluated. 不过，一旦发现STI571可减少疾病向急性发作期的发展或能清除所有残余的白血病标志分子，那就应该对干细胞移植疗法在CML治疗中的地位进行重新评价了。
- Therefore, WT1 gene is a new prognostic factor and a new marker for the detection of minimal residual disease in AL. WT1基因是一个有用的预后指标与检测微小残留病的标记。
- Monitoring the bcr/abl fusion gene by RT-nested-PCR can be used to evalute the efficacy of the therapy and detect the minimal residual disease(MRD). RT -nestedPCR方法检测bcr/abl融合基因可以作为临床诊断、判定预后的指标 ,适用于微小残留病变的监测
- Still, small volume or minimal residual disease has been recogenized as a potentially suitable target for radiolabeled antibodies.RIT... 虽然如此,放射性核素标记的抗体在治疗微小病灶中的应用前景看好。
