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- Croce and his colleges have identified a class of genes called microRNA. 和他所在学院已经发现一种被称为微RNA的基因。
- So Crochi's team purposely altered a single type of microRNA gene in lab mice. 所以克里奇的小组在实验室小鼠身上有目的地改变一个小RNA基因。
- So Croce's team purposely altered a single type of microRNA gene in lab mice. 所以C的小组故意在一只实验鼠的身上改变了一种微型RNA基因。
- Keywords microRNA(miRNA);heart development;cardiac hypertrophy; 心脏发育;心肌肥厚;
- Fourth, miRNA sequences are nearly always conserved in related organisms, whereas endogenous siRNA sequences are rarely conserved. 第四,相关生物中的微小RNA序列几乎总是保守的,而外源小型干扰RNA 序列很少是保守。
- When Weigel's group engineered plants in which the microRNA could not do its job, the plants became sick and deformed. 当魏格尔的团队以基因工程改造植物,不让该微RNA执行工作时,植物就开始生病及变形。
- The good news is Croce says the technology to manipulate the activity of microRNA already exists. 好消息是,c说抑制微RNA活动性的技术已经存在了。
- Beside human leukemias and lymphomas, microRNA genes also have been found in human lung, breast and colon cancer. 除了白血病和淋巴癌,微型RNA基因同样也在人的肺,胸和盲肠癌。
- Besides human leukemias and lymphomas, microRNA genes also have been found in human lung, breast and colon cancers. 除了人类的白血病和淋巴癌,人类肺癌,乳腺癌和结肠癌中也发现了微RNA基因。
- Croce says the next step is to find treatments that counter the effects of the altered microRNA. 声称下一步就是要发现对应变异的微RNA的治疗方法。
- No study has evaluated the association between microRNA expression patterns and colon cancer prognosis or therapeutic outcomes. 但是现在尚无有关研究来评估microRNA的表达形式与结肠癌预后或治疗结果的相关性。
- In arabidopsis, the JAW microRNA doubles over and is then captured by the RNA interference machinery, just as if it had come out of a virus. 在阿拉伯芥当中,名叫JAW的微RNA经摺叠之后,就如同来自病毒的RNA一般,被RNA干扰装置给捕捉。
- Next, the researchers examined postmortem brains of Parkinson's patients to determine which type of microRNA was noticeably deficient in the midbrain regions. 下一步;这些研究人员检测了帕金森病人死后的脑部以确定哪种信使RNA在中脑区域是明显缺乏的.
- FULL SET: A picture of a midbrain replete with dopamine neurons. Without a certain microRNA, a pattern resembling Swiss cheese would appear in this area as cells became disrupted. 组图:一张充满了多巴胺神经原的中脑图片.;缺少某种微RNA;一种类似于奶酪一样的格局显示在这个区域;像细胞损坏一样
- Chen, Hsuan-Yu (2007): Gene Signature in Non-Small-Cell Lung Cancer: Application of Gene Expression Profile and MicroRNA in Clinical Outcome (Ph.D Thesis). 陈璿宇(2007):非小细胞肺癌之基因印记:基因表现剖绘与微小核醣核酸在临床预后之应用。
- Does miRNA stimulation of translation raise a possible complication, and opportunity, in using miRNAs and small interfering RNAs as therapeutics? 把微小RNA和小RNA干涉用于治疗学中,微小RNA的翻译刺激可以带来一些困难或者可能性吗?
- Keywords miRNA;gene regulation;cancer; 基因调控;肿瘤;
- Here we summarizes the related progression in research of miRNA and liver cancer. microRNA 微小RNA
- microRNA(miRNA) microRNA(miRNA)
- microRNA (miRNA) microRNA