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- Objective To select high Lovastatin producing microbial breed by space flight. 目的选育高产洛伐他汀的红曲霉菌菌株。
- Objective:To clinically observe the effect of lovastatin on patients with unstable angina pectoris(UA). 目的:探讨洛伐他汀对不稳定性心绞痛(UA)患者的血脂、心脏缺血事件发生情况的影响。
- Methods 135 patients with hyperlipidemia were randomly allocated to two groups: Lovastatin group and XUEZHIKANG group. 方法将135例老年高脂血症患者随机分为洛伐他汀组和血脂康组；
- Objective To review the advances on lovastatin fermentation by Aspergillus terrus. 目的综述土曲霉洛伐他汀发酵研究的进展。
- The formula of fermentation medium of lovastatin form US patent 5409820 had been Optimized by Uniform Design Method. 应用均匀设计优选试验方法，采用国产原料，对洛伐他汀生产用发酵培养基配方进行了优化，取得了比较好的结果。
- HZ-818 wass selected as the adsorbent for isolating lovastatin from the filtered fermentation broth. 国产HZ-818作为分离纯化洛伐他汀的吸附剂；
- Different concentrations of lovastatin had obvious inhibitive effects on the proliferation of RMC compared with control group(P<0.01). 不同浓度洛伐他汀对大鼠系膜细胞增殖均有明显的抑制作用;与对照组比较有明显差异(P<0.;01)。
- Conclusion With the advances of basic research about fungi producing lovastatin in the molecule and cell level,the optimization of lov... 结论随着洛伐他汀产生菌的分子、细胞水平基础研究的加强,其发酵工艺的优化将更有意义。
- Abstract: Objective To isolate and purify lovastatin from fermentation broth of Aspergillus terreus by macroporous adsorptive resins. 摘要：目的 用大孔吸附树脂法分离纯化洛伐他汀，提高洛伐他汀成品收率，适应工业化生产的需要。
- Ultraviolet spectrometry and HPLC were used to determine the content of Lovastatin capsule.In the meantime,we compared the results by the two means. 用紫外分光光度法测定洛伐他汀胶囊的含量,并将测定结果与高效液相色谱法的测定结果进行比较。
- In the process of manufacturing Lovastatin Tablets, two kinds of refuses, fermentation refuse and refining refuse, are produced. 摘要 洛伐他汀生产过程中产生发酵渣和提炼渣。
- After flight, the strain was rejuvenized, segregated and selected.The content of Lovastatin produced in the solid fermentation was examined. 对搭载后的菌株进行复壮、分离和筛选,并进行固体发酵,检测发酵产物中洛伐他汀产量。
- Methods: Simvastatin was synthesized from lovastatin via several steps involving acetylization,methylation,hydrolytic decomposition and cyclization reactions. 方法:以洛伐他汀为原料,通过酰化、甲基化、水解、环合等反应合成了辛伐他汀。
- And rats of L-NNA+lovastatin-treated group were intraperitonealy injected with L-NNA at dose of 20 mg/kg daily for 3 d in the first three day of lovastatin injection. L-NNA+洛伐他汀处理组大鼠在注射洛伐他汀前3天加L-NNA(20mg/kg)腹腔注射，每天1次，连续3天。
- Furberg CD,Adama AP,Applegate WB,et al.Effect of lovastatin on early carotid atherosclerosis and cardiovascular events (ACAPS)[J].Circulation,1994,90(4):1679. 陆宗良;寇文容;徐义枢;等.;乐瓦停治疗原发性和继发性高脂血症的临床观察[J]
- This study was designed to investigate the effects of lovastatin on proliferation and gap junctional intercellular communication (GJIC) of MCF 7 human breast cancer cells. 本文探讨洛伐他汀对人乳腺癌细胞MCF-7增殖功能以及间隙连接细胞通讯(gapjunctionalintercellularcommunication,GJIC)的影响。
- Objective To study the efficacy and adverse effects of lovastatin combined with metronidazole in treatment of hyperlipidemia, and to explore its possible mechanisms. 摘要目的观察小剂量甲硝唑合洛伐他汀调治高脂血症的疗效与副作用，并探讨其可能的机理。
- Good separations of polynuclear aromatic compounds, alkylbenzenes, basic aromatic compounds, halobenzenes as well as lovastatin and simvastatin were achieved. 实验证明这种交联聚合包覆固定相对有机流动相和碱具有高稳定性。
- Objective To study the efficacy and adverse effects of lovastatin combined with metronidazole in treatment of hyperlipidemia,and to explore its possible mechanisms. 目的观察小剂量甲硝唑合洛伐他汀调治高脂血症的疗效与副作用,并探讨其可能的机理。
