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- Genetic polymorphisms of drug metabolizing enzymes. 药物代谢酶类基因多态性研究。
- Some applications of phenotyping &genotyping of drug metabolizing enzymes are also introduced. 最后主要讨论了表型分型和基因分型在药物代谢酶研究中的一些应用。
- Objective: To review the effects of the active components of Chinese herbs on drug metabolizing enzymes. 目的:综述近年来中药有效成分对药物代谢酶的影响的研究进展。
- OBJECTIVE To investigate the effect of Shengmai injection (SMI) on the drug metabolizing enzyme of liver in mice. 目的:观察生脉注射液(SMI)对小鼠肝药酶的影响。
- With the exception of drug metabolizing enzymes, drug receptors are another important kinds of proteins involved in drug response. 这些差异的产生是遗传因素与环境因素共同作用的结果，其中遗传因素为决定性因素。
- The activities of metabolizing enzymes were measured by spectrophotography, and hepatic function was determined by biochemical analyser. 结果彗星发生率染毒组显著高于对照组,肝细胞和血淋巴细胞彗星发生率显著相关。
- To investigate DNA damage of liver cells and lymphocytes of rats exposed to vinyl chloride (VC),to examine the activities of VC metabolizing enzymes including GST,CYP2E1,ADH,and ALDH, and to explore early sensitive indexes to detect damage induced by VC. [目的 ]研究氯乙烯 (VC)对大鼠肝细胞和外周血淋巴细胞DNA的损伤作用 ,及对VC代谢酶 [谷胱甘肽硫转移酶 (GST)、细胞色素P45 0 2E1(CYP2E1)、乙醇脱氢酶 (ADH)和乙醛脱氢酶 (ALDH) ]活性的影响 ; 探索VC所致损伤的早期敏感检测指标。
- This review is focused on two main types of markers of susceptibility to benzene-induced hematotoxicology, metabolizing enzymes, DNA repairing enzymes, their polymorphisms are also addressed. 介绍苯致血液毒性两大类主要的易感性标记物、代谢酶,DNA修复酶及其多态性;
- Methods:By immunohistochemical methods, we examined the expression pattern of major arachidonic acid metabolizing enzymes in 17 samples of Crohn;s disease with associated intestinal fistula. 方法:通过免疫组化考察花生四烯酸代谢的主要酶系在17例克罗恩病并发肠瘘的病变肠组织的表达情况。
- Effects of Cd on brain AChE and metabolic enzymes in tissues of T. Nilotics. 镉对罗非鱼脑AChE及组织中代谢酶的影响。
- Objective: To promote the study of drug metabolic enzymes in clinical practice. 目的:为了促进药物代谢酶在临床上的深入研究。
- Drug metabolism determines several pharmacological and toxicological properties of pharmaceuticals and is catalyzed by drug metabolizing enzymes. 药物代谢是在代谢酶催化下完成的,它决定着药物的药理学和毒理学特性。
- The team detected the effect by examining the metabolic enzyme aconitase, which is susceptible to damage from ROS. 小组监测代谢酶顺乌头酸酶以检测这种效应，这种酶是可以被活性氧的损伤作用影响的。
- Drug metabolic enzymes are one of the major factors causing the variation of drug effects as well as toxicity in pa... 结论:药物代谢酶的认识和研究有助于临床合理用药和减少药物不良反应。
- Malate dehydrogenase (MDH) is an essential metabolic enzyme, which has high economic value in protein research. 苹果酸脱氢酶不仅是一种重要的糖代谢酶，而且具有较高的经济价值和理论研究价值。
- Skin is one of the main extrahepatic metabolic organs and expresses many kinds of metabolic enzymes. 皮肤是肝外药物代谢的主要器官之一,有多种代谢酶表达。
- There are three oxalate metabolism enzymes in organisms: oxalate oxidase, oxalate decarboxylase, and oxalyl-CoA decarboxylase/formyl-CoA transferase. 生物草酸代谢酶有草酸氧化酶、草酸脱羧酶和草酰辅酶A脱羧酶／甲酰辅酶A转移酶。
- For example, research in the area of polymorphism of Phase I and Phase II metabolizing enzymes, CYP mediated drug metabolisms, high throughput ADME assessment and a more molecular focus. 如，相关药物代谢酶的基因多态性及指导临床合理用药的应用、中草药与药物相互作用相关机制及在肾移植病人的应用、体外ADME高通量筛选和评价技术、中草药与药物代谢性相互作用及相关机制研究等。
- To research the effect of cured pig's Cysticercosis,this experiment detected metabolic enzymes and fat levels in 26 pigs that disease are cured. 为了研究治愈囊虫病猪的机体康复转化的效果,本实验对26头治愈囊虫病猪的酶类和脂质水平进行了分析检测。
- Acting on entero-transport protein and intestinal mucosa metabolic enzyme,grapefruit juice can change the bioavailability of many oral drugs. 葡萄柚汁通过对肠道转运蛋白及肠黏膜上皮细胞上代谢酶的影响从而改变很多口服药物的生物利用度。
