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- Gabapentin Acts within the Locus Coeruleus to Alleviate Neuropathic Pain. 加巴喷丁作用于蓝斑核可减轻神经性疼痛。
- The spontaneous firings of nucleus locus coeruleus (LC) were recorded. 它们可为自然痛刺激所兴奋,可被吗啡等镇痛剂所抑制。
- The glucocorticoids then activate a brain region called the locus coeruleus. 接著,糖皮质素会活化脑中一个称为蓝斑核的所在;
- Aim: To demonstrate neurotransmitters in fibers projeced to dorsal hippocampus from locus coeruleus in rats. 目的:观察大鼠蓝斑至背海马投射纤维的递质性质。
- Results: HRP labelled cells,TH labelled cells and TH-HRP double labelled cells were found in locus coeruleus. 结果:在双侧蓝斑内可见到HRP标记细胞、TH阳性反应细胞和TH-HRP双标细胞,同侧明显多于对侧。
- Microinjection of glutamate into ipsilateral locus coeruleus (LC) decreased the amplitude of P2 and P3 significantly. 同侧蓝斑(LC)内微量注射谷氨酸钠使P2,P3波的幅值明显降低。
- In their search for alternatives, researchers have sought to target the stress response upstream of the locus coeruleus and amygdala. 研究人员在寻找替代性药物时,将目标放在蓝斑核及杏仁体上游的压力反应。
- Serotonin normally arrives in the frontal cortex by way of the raphe nucleus, a structure that also communicates with the locus coeruleus. 血清张力素除了其他的作用外,对于情绪及睡眠周期的调节也可能相当重要。
- Conclusion: Propofol decreases the concentration of NE in locus coeruleus, which may be its possible central mechanism of circulation inhibition. 本研究证实:异丙酚可降低蓝斑区NE的浓度,可能是其引起循环抑制的中枢机制之一。
- The divergent axon collaterals from neurons in locus coeruleus have been in vestigated by means of fluorescent double labeling technique in 36 rats. 用荧光素双标记法研究了36只大鼠蓝斑向前额叶皮质、海马、丘脑、小脑和脊髓的分支投射。
- Ketamine increases the concentration of NE in locus coeruleus, which may be considered as a possible central mechanism of its circulation excitement. 氯胺酮可升高蓝斑区NE的浓度, 表明氯胺酮可能对心血管中枢也有一定的兴奋作用。
- Abstract: Objective To investigate the changes in the firing activity of noradrenergic neurons in the locus coeruleus (LC) in a rat model of Parkinson disease (PD). 摘要:目的 观察帕金森病模型大鼠蓝斑核肾上腺素能神经元电活动的改变。
- Objective To explore the function and relationc of Nucleus Raphe Magnus (NRM) and Locus Coeruleus (LC) in the regulating gastric motility ty electric needle point in the rabbits. 摘要目的:探讨中缝大核和蓝斑核在针刺调节胃运动中的作用和关系。
- Objective: The present study is to explore the effects on cardiovascular activities by the injection of substance P (SP) into locus coeruleus complex area (Lc-Sc). 目的:探讨P物质在蓝斑复合核对心血管活动的影响。
- Immunohistochemistry was used to detect the protein expression of nNOS in lumber spinal cord (L 4-L 5), locus coeruleus (LC) and periaqueductal gray (PAG) in morphine withdrawal rats. 电针结束后 30min ,取大鼠脊髓和脑 ,采用免疫组织化学方法和计算机图象分析技术 ,对脊髓腰膨大 (L4 L5)、蓝斑 (locuscoeruleus ,LC)、中脑导水管周围灰质 (periaqueductalgray ,PAG)nNOS的原位表达进行观察及半定量分析。
- Fos immunoreactive cells were mainly located in the dorsal raphe nucleus (DR),nucleus raphe magnus (NRM), locus coeruleus (LC), the ventrolateral of periaqueductal gray (vlPAG), hypothalamic paraventricular nucleus (PVN). Fos阳性细胞主要分布于中缝背核 (DR)、中缝大核 (NRM )、蓝斑 (LC)、中脑导水管周围灰质腹外侧 (vlPAG)和下丘脑室旁核。
- Retrograde tracing revealed that regenerated axons originated from brain stem nuclei, including red nucleus, locus coeruleus, raphe nucleus, vestibular nucleus, and reticular formation. 神经逆向追踪结果证实移植细胞后可帮助上脊髓神经核包括红核、蓝斑核、缝核、前庭核及网状结构内的神经元再生。
- Gi_2 proteins in chronic morphine dependent group and chronic abstinence group were significantly decreased in nucleus accumbens (P<0.01) and significantly increased in locus coeruleus (P<0.05) compared with that of chronic control group. 慢性吗啡依赖组和戒断组与慢性空白对照组比较;NAc区Gi2蛋白水平明显降低(P<0·01);LC区Gi2蛋白水平明显升高(P<0·01)。
- Abstract Previous studies in our laboratory have shown that hypothalamic arcuate nucleus (ARC) and locus coeruleus (LC) play an important role in pain modulation and acupuncture analgesia. 摘要 该研究室以往工作表明,下丘脑弓状核(ARC)和蓝斑(LC)在痛觉调制和针刺镇痛中具有重要作用。
- Keywords Ketamine;Locus coeruleus;Noradrenaline; 氯胺酮;蓝斑;去甲肾上腺素;