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- lineage specific gene 种系特异性基因
- As an ideal model for in vitro ES cells differentiation, EBs recapitulate many aspects of the lineage specific differentiation programs and temporal and spatial gene expression patterns of early embryogenesis. 作为ES细胞体外分化的理想模型,EBs可以再现胚胎早期发育过程中的谱系特异性分化程序及基因时空表达模式的诸多方面,因此被广泛用于研究胚层间相互诱导、器官空腔化形成等胚胎早期发育事件。
- Platelet and T cell activation antigen 1 (PTA1) was initially reported by Burns in 1985 with the name TLiSA1 (T lineage specific activation antigen 1, TLiSA1 ), and was renamed as PTA1 in 1989 because of its expression on platelet as well. 血小板和T细胞活化抗原1(platelet and T cell activation antigen 1,PTA1)最早在1985年由Bums等发现。 由于其表达于人活化T细胞而被命名为TLiSA1抗原(T lineage specific activation antigen 1,TLiSA1)。
- It enables a specific gene to be located on a particular restriction enzyme fragment. 它就能使专一的基因被定位于特定的限制性内切酶切成的片段上。
- It was clear in RT-PCR that human myocardial specific gene MLC-2V. MLC-2A. a-MHC. CTnT. RT-PCR显示,移植hEBDs的鸡胚心肌中有人心肌特异性的基因MLC-2V、MLC-2A、-MHC、CTnT、ANP与NKx-2.;5等表达。
- Howeer, uniparental ES cell research faces the biological hurdle of genomic imprinting, in which specific gene expression patterns are dictated by the parental origin. 然而,单系胚胎干细胞研究面临着基因组印迹的生物学障碍,即特殊的基因表达模式受原始亲代的控制。
- This would seem to prevent researchers from making dog "knockouts" lacking a specific gene or engineering dogs that produce mutant forms of a gene. 因为缺少一种特定的基因或能产生突变基因的转基因狗,研究人员可能无法进行狗基因敲除。
- Methods The insert gene region of TA-GVHD and specific gene region of the Y chromosome was detected using PCR technique. 方法女性患者输血前后自身对照,采取静脉血样,用PCR技术进行TA_GVHD插入基因片段及人Y染色体特异基因荧光检测。
- Validation of a Rice Specific Gene, Sucrose Phosphate Synthase, Used as the Endogenous Reference Gene for Qualitative and Real-Time Quantitative PCR Detection of Transgenes. 一种水稻特异基因-蔗糖磷酸合成酶基因的确定,用作定性和实时定量PCR检测转基因的内标准基因。
- Conclusion:The data suggest the telomerase is a tumor specific gene marker,and may play an important role in early diagnosis and treatment of gastric carcinomas. 结论:端粒酶是特异性较强的恶性肿瘤基因标志,有可能成为胃癌早期诊断和治疗的理想标记物。
- Frozen brain slabs are kept at cryogenic temperatures until they are further sliced and eventually probed with RNA to look for specific gene expression. 冷冻的大脑切片被保存在低温条件下,直到进行进一步切片处理并最终用RNA加以探测,以寻找特定的基因表达。
- Conclusion The data suggest that telomerase is a tumor specific gene marker, and may play an important role in early diagnosis and treatment of colorectal carcinomas. 结论端粒酶是特异性较强的恶性肿瘤基因标志,有可能成为大肠癌早期诊断和治疗的理想标志物。
- One generation of a specific lineage. 一代家族某种特殊世家的后代
- We find that 26 of 39 autosomal chromosome arms show consistent large-scale copy-number gain or loss, of which only a handful have been linked to a specific gene. 我们发现, 26 39常染色体臂展一贯的大规模拷贝数的收益或亏损,其中只有极少数已经联系到一个特定的基因。
- Antisense oligonucleotides have been successfully employed to inhibit and modulate specifically gene expression. 反义寡聚核苷酸已成功用于对基因表达的特异性调控与抑制。
- Glioma cells with mutation in a specific gene called the phosphatase and tensin homolog gene, or PTEN, seemed more resistant to the immune system than glioma cells with normal PTEN function. 带有称作磷酸酶-张力蛋白基因(PTEN)突变的胶质瘤细胞,对免疫系统要比PTEN功能正常的胶质瘤细胞,看上去更有抗药性。
- A diagram showing a family lineage; a family tree. 宗谱一个显示家庭后裔情况的图表
- Moreover, the pediatric BCR_ABL specific genes can be used to correctly discriminate independent adult BCR_ABL cases. 此外,一组儿童白血病亚型(BCR_ABL)的标志基因能够准确预测成人白血病中的该亚型。
- One that induces, especially a substance that is capable of activating specific genes within a cell. 诱导物诱导的人或事物,尤指在细胞中可以激发产生某种基因的物质。
- Transgenic or knockout of specific genes have led to the development of rodent models of spontaneous colitis. 转基因和基因敲除动物模型带动了自发性结肠炎动物模型的发展。