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- The conclusion is, it probably can activate a certain intracellular signaling, but really, it depends on an individual's genetic background. 结论是，它很可能激活某些细胞内信号，但实际上，它取决于个人的遗传背景。
- Extracellular signal-regulated kinase(ERK) signaling pathway is a critical signaling pathway that transduce the intracellular signal. 细胞外信号调节激酶信号通道是一条重要的细胞内传导通道。
- Moreover, non-cytotoxic agents such as small molecules targeting receptor tyrosine kinases and intracellular signaling pathways have been used in the clinical field. 替莫唑胺及亚硝基脲类药物耐药性得到了部分解决以及非细胞毒性药物如酪氨酸激酶抑制剂及细胞间信号传导通路抑制剂在临床中的应用。
- Reactive oxygen species (ROS) and calcium signal constitute the most important intracellular signaling systems that participate in the regulation of multitude cellular functions. 活性氧信号和钙信号广泛存在于机体内,两者相互作用,共同参与调节机体多种生理功能及病理过程。
- Cardiac hypertrophy is the consequence of hypertrophic stimulus-induced changes in gene expression,which is linked by intracellular signal transduction. 心肌肥厚是肥大刺激诱导核内基因异常表达的结果，细胞内信号转导通路是肥大刺激与核内基因转录活化的偶联环节。
- Objective To deterimine the phagocytosis of fibronectin (FN) by retinal pigment epithelial (RPE) cells and its related intracellular signal transduction pathways. 目的 探讨视网膜色素上皮 (retinalpigmentepithelium ,RPE)细胞对纤维连接蛋白(fibronectin ,FN)的吞噬及相关细胞内信号传导通路的作用。
- Objective To explore the effecte of cigarette smoke extract (CSE) on expression of interleukin-8 (IL-8) mRNA in human peripheral blood mononuclear cells (PBMC), and the intracellular signaling pathway involved. 目的 探讨香烟烟雾提取物 (CSE)对人外周血单个核细胞 (PBMC)IL 8mRNA表达的影响及其细胞内信号途径。
- Endothelin can affect the contractile properties of cardiacmyocyte, stimulate myocyte growth and myofibrillogenesis, and increase resistance to apoptosis by intracellular signaling pathways. 内皮素通过多种心肌细胞内信号途径调节心肌细胞的收缩特性,刺激心肌细胞生长和肌原纤维的产生、抗凋亡等作用。
- Shear stress can regulate vascular endothelial cell(EC)functions through membrane sensing,intracellular signal transduction,and modulation of gene and protein expressions. 剪切力可经由应力感受、信息传递和基因与蛋白质的表达来调控血管内皮细胞的功能。
- ATP-sensitive potassium channels (KATP), which act as a key “end-effector” in the pathways of intracellular signaling transduction, play an important role in early and delayed preconditioning. ATP敏感性钾通道（KATP通道）作为心肌缺血预适应（早期与延迟效应）细胞内信号转导途径中的一种“终末效应子”，在缺血预适应中起重要作用。
- Activation and proliferation of HSC are regulated by several cytokines or signal regulatory proteins in vivo.The surface receptor can activate intracellular signal pathways with cytokines. 肝星状细胞在活化增殖过程中受多种细胞因子或蛋白的调控,通过表面受体激活信号转导网络系统,促使肝纤维化的发生发展。
- Protein phosphorylation, which is mediated by enzymes, called protein kinases, is a major mechanism for transducing external stimuli into intracellular signals. 在这其中，把细胞外刺激转导到细胞内是通过蛋白质磷酸化来完成的，而蛋白质磷酸化又被蛋白激酶介导。
- Finally, oxidants are involved in intracellular signalling pathways leading to activation of transcription factors and thus influencing gene transcription. 最后，氧化物通过干预细胞信号转导途径，导致转录因子的激活，而影响基因的转录。
- They transduce or convert extracellular stimuli into intracellular signals through a number of signaling pathways, including neurotransmitters, light, hormones, lipids, and proteins. 他们通过许多信号途径将胞外刺激转导或是转化成胞内信号，包括神经递质，光，激素，脂质和蛋白质。
- intracellular signal transduction 细胞内信号传导
- Several hypotheses have been advanced that link physical forces to intracellular signalling pathways, but in many cases the molecular mechanisms of mechanotransduction remain elusive. 已经提出了几个假说来连接物理力和细胞内信号转导通路但是许多情况中机械转导的机制还不清楚。
- A red light is usually a signal of danger. 红灯通常是危险的信号。
- I stood watching for the signal to change to green. 我站着等待交通信号转为绿灯。
- Let's set the clock by the radio time signal. 咱们照着收音机的报时信号把钟对一对。
- A red lamp is often a danger signal. 红灯常常是危险的信号。
