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- OBJECTIVE To prepare enteric microspheres containing thymosin, and evaluate its in vitro release profiles and in vivo bioactivity. 目的制备胸腺肽肠溶微球,并对其体外释药特性及调节免疫的体内活性进行评价。
- in vitro release profile 体外释放
- Objective To prepare the sustained-release tablets of tiopronin and investigate the release profile in vitro of the sustained-release tablets. 目的 制备硫普罗宁缓释片并对其体外释放度进行考察。
- OBJECTIVE To prepare hydroxycamptothecinsemisolid lipid nanoparticles(HCPT-SSLN) and study the release profile in vitro. 目的:制备羟基喜树碱的半固体脂质纳米粒(HCPT-SSLN),初步考察其体外释药规律。
- OBJECTIVE To prepare Tandospirone citrate(TDS) osmotic pump tablets and investigate the factors influencing the drug release profile in vitro and drug release mechanism. 目的制备枸橼酸坦度螺酮(TDS)渗透泵型控释片,考察影响其释药行为的因素,并探讨释药机理。
- ABSTRACT Objective To prepare capreomycin sulfate liposomes to develop a method for determining its drug content and entrapment efficiency and to study the release profile in vitro. 目的制备硫酸卷曲霉素脂质体，建立含量和包封率的测定方法，初步考察其体外释放规律。
- The results showed that the amount of HPMC and Carbomer had remarkable effects on the in vitro release of capsules. 结果表明羟丙甲纤维素与卡波姆对阻滞胶囊体外释放度影响较大。
- Objective: To investigate in vitro release characteristics of collagen double layer minipellet of erythropoietin(EPO). 目的:对红细胞生成素胶原蛋白双层微条的体外释放特性进行研究。
- Methods The floating behavior and the in vitro release characteristics of cimetidine was used as the screening indexes. 方法 以漂浮性、释药性能为指标，对处方和工艺进行单因素考察。
- Objective To study the release kinetics of theophylline from the hydroxypropyl methylcellulose (HPMC) matrix tablets in vitro release test. 目的研究以羟丙基甲基纤维素(HPMC)为基材的茶碱片剂在体外溶出的动力学规律。
- Objective: To study the preparation and the in vitro release characteristics of scutellarin sustained-release dropping pills (Scu SDP). 目的:研究灯盏花素缓释滴丸的制备方法及其体外释放特征。
- In vitro release test showed a burst release of DGR from microspheres, followed by sustained release of 50% total activity over 15 days. DGR微球的体外释放呈现两个时相,15d释放大约DGR总活性的50%25。
- Objective To investigate factors influencing the in vitro release of sulindac from the hydrogel matrix tablets and optimize the formulation. 目的 研究舒林酸亲水凝胶缓释骨架片体外释放的影响因素，筛选最优处方。
- OBJECTIVE To select the in vitro release medium for elevating the colon-specific effect of preparations prepared with konjac glucomannan. 目的筛选合适的释放介质,用于魔芋胶为载体结肠定位给药系统的体外评价。
- CONCLUSION:A good correlativity was showed between in vivo absorption and in vitro release of theophylline sustained release tablets. 结论：茶碱缓释片的体内吸收百分率与体外释放百分率间存在良好的相关关系。
- OBJECTIVE To investigate the effect of coating on Sodium ferulate porosity osmotic pump tablets in vitro release and to optimize the formulation. 目的考察包衣处方对阿魏酸钠口服微孔渗透泵控释片体外释药性质的影响,并优选最佳包衣处方。
- In vitro release of enteric capsules of Poecilobdella manillensis Lesson extract using sodium carboxy-methyl starch as disintegrant was investigated. 测定了以羧甲淀粉钠为崩解剂的菲牛蛭提取物肠溶胶囊的体外释放。
- Methods:We carried out the trial by using separated skin of rats and in vitro release transdermic instrument made by ourselves. 方法：采用大鼠离体皮肤和自制体外释放透皮装置试验。
- OBJECTIVE：To evaluate the correlativity between in vitro release and in vivo absorption of theophylline sustained release tablets. 目的：评价茶碱缓释片的体外释放与体内吸收的相关性，为其质量控制提供实验依据。
- OBJECTIVETo prepare the pulsatile contro ll ed release tablets (PCRT) of diclofenac sodium (DS) as a drug model and investig ate the influence factors in vitro release. 以双氯灭痛为模型药物,研制脉冲控释片并考察其体外释放的影响因素。
