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- imatinib resistant cell line 伊马替尼耐药细胞株
- Objective To study drug resistant mechanism and reversal of glioma we established C 6 MDR drug resistant cell line(C 6/adr). 目的 为研究脑胶质瘤的耐药、机理及逆转 ,建立了C6耐阿霉素细胞株 (C6/adr)MDR细胞系。
- Objective To investigate the restoration of the subcellular distribution of daunorubicin in the P glycoprotein mediated multidrug resistant cell line K562/ADR by quercetin. 目的研究槲皮素处理前后柔红霉素(DNR)在耐药细胞株K562/ADR亚细胞结构的不同分布。
- Objective: To investigate the inhibitory effect of ampelopsin (AMP) combined with adriamycin (ADR) on growth of human leukemia multidrug resistant cell line K562/ADR. 目的:研究蛇葡萄素与阿霉素合用对人白血病多药耐药细胞株K562/ADR增殖的抑制作用及其机制。
- Objective To explore the reversal effect of cyclosporin A(CsA) in combination with cytokines on multidrug resistant cell line K562/A02. Method The cytotoxicities of daunorubicin(DNR) were assayed by MTT method. 目的探讨环孢菌素A(CsA)联合细胞因子对耐药细胞系K562/A02的逆转作用。 方法以甲基四唑蓝法测定柔红霉素(DNR)的细胞毒性;
- Objective:The study was designed to examine the expressions of vascular endothelial growth factor C(VEGF C) mRNA and protein in human breast cancer cell line MCF 7 and drug resistant cell line MCF 7/Adr. 目的 :检测血管内皮生长因子C(vascularendothelialgrowthfactorC ,VEGF C)mRNA和蛋白在人乳腺癌细胞株MCF 7及其耐药株MCF 7/Adr中的定位、定性表达。
- Objective:To study the effects of oridonin on inducing the multi-drug resistant cell line K562/A02 to apoptosis and reversing their multi-drug resistance. 目的:探讨冬凌草甲素诱导多药耐药细胞系K562/A02凋亡、逆转耐药性的作用。
- Conclusion A multidrug resistance cell line (SPC-A-1/CDDP) from human lung adenocarcinoma is established.It can be used to downstream experiment. 结论本研究建立了稳定的人肺腺癌多药耐药细胞系(SPC-A-1/CDDP),可应用于下游实验。
- Flow cytometry was used to detect theexpression of HLA-l, HLA-2, B7-l, B7-2 in parent cell lines (COC1 andSKOV3 ) and multidrug resistant cell sublines (COCI/DDP andSKOV3/Adr). 运用流式细胞仪技术检测了各种不同细胞亚株的HLA-1、HLA-2、B7-1、B7-2的表达。 结果:耐药亚株COC1/DDP、SKOV_3/Adr和亲本株COC1、SKOV_3的N-GSLs表达有差异,COC1/DDP、SKOV_3/Adr的CMH表达较COC1、SKOV_3强。
- AIM and METHODS: Matrine (50mg/L) potentiated the cytotoxicity of daunorubicin (DNR) in human leukemia multidrug resistance cell line K562/A02 by MTT assay. 方法和结果:经MTT法发现苦参碱50mg/L能增加K562/A02对柔红霉素的敏感性,使柔红霉素半数抑制浓度(IC50)由14?92mg/L降至8?29mg/L,部分逆转了K562/A02对柔红霉素耐药性,逆转倍数为1?80倍。
- So, we first studied the innate resistant mechanism of HCC Bel7402 cell line, and then we successfully established a 161 fold resistant cell line named Bel5-FU20000 in vitro by continuous stepwise exposure of Bel7402 cells to 5-FU for 6 months. 为此,我们首先研究了人肝癌Bel_(7402)细胞株的天然耐药性及其机制,继而又以Bel_(7402)作为亲本细胞,经过体外约6个月的多步骤连续5-FU筛选,得到了对5-FU耐药约161倍的5-FU耐药细胞系Bel_(5-FU20000),并对其生物学特征及耐药机理进行了研究。
- Some compounds exhibit cytotoxicity toward KB cells and P388 murine leukemia cells,and inhibitory activity against P-glycoprotein over expressing of adriamycin resistant cell line,K562/Adr cells. 一些成分在抑制KB细胞、P388白血病细胞和P-糖蛋白方面显示了较好的活性。
- KBV200 multidrug resistance cell line KBV200细胞株
- Reversal Effect of Verapamil on Multidrug Resistant Cell Line HL-60/ADR 异搏定逆转HL-60/ADR细胞株耐药机理的初步探讨
- Maintain the cell line equipments. 负责尚能电池线设备维护。
- We have obtained a stable UT-A2-FRT cell line. 经BSD筛选21 d后得到稳定表达UT-A2的细胞株;
- Materials1) Bel7402 cell line and COS? 肝癌Bel7402细胞系和COS7细胞系
- HL60/DNR is a model cell line of MDR1. HL60/DNR为典型的表达MDR1的细胞株
- Reversion of drug resistance in intrinsic drug resistant cell line GRC 1 逆转肾癌细胞系GRC-1耐药的实验与机理研究
- THE CHARACTERIZATION IN MULTIDRUG RESISTANT MECHANISMS OF A HUMAN OVARIAN CARCINOMA DRUG RESISTANT CELL LINE COC_1/DDP 人卵巢癌多药耐药细胞系COC_1/DDP的耐药机制探讨