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- Objective To clarify the significance of antibodies to hypervariable region 1(HVR 1) of hepatitis C virus (HCV) in chronic HCV-infected patients. 目的 探讨慢性丙型肝炎病毒 (HCV)感染者血清中抗高变区 1 (HVR1 )抗体的多型性及其临床意义。
- E2 protein, including hypervariable region 1 (HVR1) in the N-terminal region, contains some epitopes that can induce neutralizing antibodies. 包括高变区的E2蛋白含有中和性抗原表位,能诱导机体产生中和性抗体。
- Objective:To acquire a series of high cross_reactive hypervariable region 1(HVR1) peptides of HCV isolated in China and their cocktail. 目的 :研究丙型肝炎病毒 (hepatitisCvirus ,HCV)第一高变区 (hypervariableregion 1,HVR1)抗原的交叉反应性 ,获得适合我国HCV感染株的高交叉反应性HVR1序列及其组合。
- Aim To study the sequence diversity of the hypervariable region 1(HVR1) in the putative envelope protein E2/NS1 of genotype III/2a HCV in Chinese patients. 目的研究中国丙型肝炎患者III/2a型丙型肝炎病毒(HCV)包膜蛋白E2/NS1高变区1(HVR1)序列变异的规律及意义。
- The extremely high variability of HCV especially at the hypervariable region of its envelope protein draws back the research to develop a vaccine against it in the traditional ways. 由于HCV具有不同的基因型,基因突变率高,尤其是包膜蛋白中的高变区,使得传统的疫苗制备方法在HCV面前显得束手无策。
- The invention discloses a hypervariable region 1 antigen in hepatitis C virus (HCV), and also discloses the purpose of the antigen in the preparation of hepatitis C virus detection reagent. 本发明公开了本发明提供丙型肝炎病毒(HCV)第一高变区抗原,还公开了该抗原在制备丙型肝炎病毒检测试剂中的用途。
- hypervariable region(HVR) 高变区
- hypervariable region of VP2 gene VP2蛋白基因高变区
- Keywords hepatitis C virus;hypervariable region 1;cross_reactivity; 肝炎病毒;丙型;第一高变区;交叉性;
- Dynamic variation of HCV hypervariable region gene and homology analysis HCV高变区基因变异的动态观察及同源性分析
- Keywords Hepatitis C virus;Hypervariable region;Antigens;synthetic;Vaccine; 肝炎病毒;丙型;高变区;抗原;合成;疫苗;
- Most insect do not live in polar region. 大多数的昆虫不在极地地区生存。
- The earthquake may cause a region to fall in. 地震可以使一个地区下陷。
- Cellular immune response after immunizing mice with eukaryotic plasmid carrying HCV hypervariable region 1related gene 丙肝病毒高变区1相关基因免疫小鼠诱导细胞免疫反应的研究
- To study the immune response induced by tandem gene of mimic epitopes in hypervariable region 1 of HCV 高变区1模拟表位串联基因诱导免疫应答的实验研究
- The heterogeneity of HCV quasi-species in the hypervariable region and its relationship to interferon therapy 丙型肝炎病毒高变区准种异质性与干扰素疗效的关系
- Storms spring up easily in this region. 这个地区很容易发生风暴。
- A Study on Variation of Hypervariable Regions of HIV- 1 Env gene in vitro 体外传代HIV-1包膜基因高变区变异性研究
- Sequence Variations of the Hypervariable Region of HCV and Their Clinical Significance 丙型肝炎病毒高变区序列变化及其临床意义
- He is earning a salary in the region of25,000. 他当时的薪金在25,000英镑左右。