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- herpes simplex virus gene 单纯性疱疹病毒基因
- Herpes Simplex Virus( HSV) encephalitis has its own neuroanatomy. 单纯疱疹病毒脑炎有特有的神经解剖学特征。
- Objective To evaluate the bystander effect in the retrovirus vector the herpes simplex virus thymidine kinase gene Ganciclovir system (RV HSV tk GCV). 目的 研究反转录病毒载体 (RV) -单纯疱疹病毒胸苷激酶基因 (HSV tK) -环丙氧苷 (GCV)系统中的旁观者效应。
- Herpes simplex virus glycoprotien D gene was amplified from HSV 2 Sav strain. The D gene fragment was cloned into M13mp18 and M13mp19 and sequenced. 从单纯疱疹病毒2型（HSV?2）Sav株中扩增糖蛋白D（gD）基因646bp片段，克隆入M13mp18、M13mp19测序载体。
- Herpes simplex:Infection caused by herpes simplex virus. 单纯疹: 亦称感冒疮或发热性疹。由单纯疹病毒引起的感染疾
- Herpes simplex：Infection caused by herpes simplex virus. 单纯疹:亦称感冒疮或发热性疹。由单纯疹病毒引起的感染疾病。
- Viral infection, caused by Herpes Simplex Virus Type 2 and Type 1. 病毒感染,单纯疱疹病毒引起的1型和2型。
- Herpes simplex: Infection caused by herpes simplex virus. 单纯疹:亦称感冒疮或发热性疹。由单纯疹病毒引起的感染疾病。
- This is typical for Herpes simplex virus (HSV) infection. 为典型的单纯疱疹病毒(HSV)感染。
- Herpes Simplex Virus (HSV) encephalitis has its own neuroanatomy. 单纯疱疹病毒脑炎有特有的神经解剖学特征。
- Objective To study the mechanism of bystander effect in herpes simplex virus thymidine kinase(HSV TK)/Ganciclovir(GCV) mediated gene therapy. 目的 探讨用单纯疱疹病毒胸腺嘧啶核苷激酶（HSV?TK）/丙氧鸟苷（GCV） 系统进行基因治疗时发生的旁观者效应机制。
- Herpes simplex virus (HSV) is a rare cause ofhepatitis in adults. 单纯疱疹病毒是成人肝炎的罕见病因。
- Herpes simplex virus (HSV) gains entry through abraded skin or mucosal tissue. 单纯疱疹病毒通过破损皮肤或粘膜组织进入人体。
- Objective To evaluate the efficacy of gene therapy with herpes simplex virus thymidine kinase (HSV - tk) gene transfer followed by ganciclovir (GCV) therapy in lung adenocarcinoma. 目的探讨单纯疱疹病毒胸苷激酶(HSV-tk)基因转染联合抗病毒药物更昔洛韦(GCV)对人肺腺癌细胞系的杀伤作用。
- Objective To investigate the killing effect of herpes simplex virus thymidine kinase/gancyclovir (HSV tk/GCV) suicide gene therapy system on retinoblastoma (Rb) cells and the mechanism of bystander effect. 目的 研究单纯疱疹病毒胸腺嘧啶核苷激酶 /更昔洛韦 (herpessimplexvirusthymidinekinase /gancyclovir,HSV tk/GCV)自杀基因系统对视网膜母细胞瘤 (retinoblastoma ,Rb)细胞的体外杀伤作用以及旁观者效应发生的机制。
- Objective: To evaluate the efficacy of gene therapy with the herpes simplex virus thymidine kinase (HSV TK) gene transference followed by ganciclovir (GCV) therapy in ovarian cancer. 目的：探讨单纯疱疹病毒胸苷激酶（HSV－TK）基因转染联合抗病毒药物羟基无环鸟苷（GCV）对人卵巢癌细胞系的杀伤效应。
- Objective:To evaluate the treatment effect of retrovirus mediated herpes simplex virus thymidine kinase(HSV 1 tk) gene transference followed by administration of ganciclovir(GCV) and acyclovir(ACV) on ovarian epithelial cancer cells. 目的 :探讨逆转录病毒载体介导的单纯疱疹病毒胸苷激酶 (HSV1 tk)基因转染 ,联合抗病毒药物羟甲基无环鸟苷 ( ganciclovir ,GCV)和无环鸟苷 (acyclovir ,ACV )对人卵巢上皮癌 (OEC)细胞系TYK的杀伤作用。
- TK-gene system (retrovirus transfer of the herpes simplex virus thymidine kinase gene) is one of the much more mature plans. We have succeeded in transmitting herpes TK gene into human pancreatic cancer cells, named SW1990 by retrovirus. 由缺陷型逆转录病毒介导的TK基因系统（RV－HSV－TK）是众多肿瘤生物治疗方法中一个技术较为成熟的方案，本实验采用该系统在体外成功地转染了人胰腺癌细胞株SW1990并能够稳定传代培养，转染了TK基因的SW1990细胞（SW±K），其生长曲线与未转染的SW1990细胞无差异。
- METHODS HPVB19, toxoplasma (TOX), RV, Herpes simplex virus (HSV) and other pathogenic gene were detect ed by PCR, RT PCR and B19 viral location was studied in cardiac tissues by ISH in 79 cases of CHD and 46 cases without CHD of children. 方法 采用 PCR;RT- PCR及 ISH等分子生物技术 ;对 79例先心病和 46例非先心病的先心病心肌组织中HSVB19;RV;TOX等病原基因进行检测及 B19病毒在心肌细胞内定位研究 .
- The vectors which are used in gene therapy include adenoviral (Ad) vectors, retroviral (RV) vectors, adeno-associated virus (AAV) vectors, herpes simplex virus (HSV) vectors and hybrid viral vector. 目前介导基因转移的病毒载体包括腺病毒(adenoviral，Ad)载体、逆转录病毒(retroviral，Rv)载体、腺相关病毒(adeno一assoeiated virus，AAv)载体、单纯疙疹病毒(herpes simPlex virus，Hsv)载体以及多种形式的嵌合病毒载体等。
