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- Background: Hepatic ischemia reperfusion (HIR) injury is a common acute disease of surgery. 肝脏缺血再灌注损伤(Hepatic ischemia reperfusion injury,HIR)是指肝脏缺血后重获血流灌注或氧供后,肝脏损伤会在缺血缺氧损伤的基础上进一步加重。
- Protective effect of heme oxygenase on hepatic ischemia reperfusion injury in rats FENG Zhi-jie, CHEN Xiang-ping. 血红素氧合酶;一氧化碳;肝;缺血再灌注损伤;氧化性应激
- Objective:To evaluate the role of oxygen free radicals in hepatic ischemia and reperfusion injury(HIRI) and the influence of tiopronin. 目的:探讨氧自由基在肝缺血再灌注损伤(HIRI)中的作用及凯西莱的防护作用。
- Objective: To study the effects of the preconditioning with enflurane and isoflurane on hepatic ischemia and reperfusion injury. 目的: 研究安氟醚和异氟醚预处理对肝脏缺血/再灌注损害的影响。
- Objective To study the effects of heat shock proteins (HSPs) in the course of hepatic ischemia reperfusion injury (HIRI), and analyze its mechanism. 目的了解热休克蛋白在肝缺血再灌注损伤过程中所处的位置、作用及其相关机理。
- Method: Hepatic ischemia and reperfusion medel in 60 SD rats was made by hepatic veins and artery reperfusion for 60 minutes following hepatic portal vein and artery occlusion for 30 minutes. 方法:建立SD大鼠肝脏缺血再灌注模型,第一肝门持续阻断30min后开放60min,60只大鼠随机分为6组,每组10只:A组(正常对照组),无肝脏缺血再灌注; B组(缺血再灌注组);
- After hepatic ischemia for 15 minutes and after reperfusion for 1 hour, 3 hours and 24 hours respectively, the hepatic tissue were resected for determining the activity of ATPase and for enzyme-histochemistry dyeing. 肝脏缺血15min,分别于再灌注后1、3、24h取肝组织测定Na+-K+-ATP酶、Ca2+-Mg2+-ATP酶水平,并行酶组织化学染色,观察Ca2+-ATP酶的活性变化。
- Hepatic ischemia reperfusion leads to oxygen free radical producing excessively, calcium overload and ATP depletion, which destroy bile canalicular F-actin directly or indirectly. 4. 3.肝脏缺血再灌注造成氧自由基过量生成,细胞钙超载,ATP耗竭,直接或间接破坏胆小管F-actin微丝。
- hepatic ischemia reperfusion injury 肝缺血再灌注损伤
- Hepatic ischemia and reperfusion injury 肝脏缺血再灌注损伤
- Hepatic ischemia reperfusion injure 肝缺血再灌注损伤
- CONCLUSION IPC protects liver from I/R injury. The mechanism may be inactivation of the oxygen free radicals, and it is unlikely that NO is involved in hepatic ischemic preconditioning. 主题词再灌注损伤/预防和控制;肝/血液供给;局部缺血/治疗;疾病模型,动物
- hepatic ischemic reperfusion injury 肝脏缺血再灌注损伤
- Experimental Studies on Protective Effect of Intra Oxygen Injection Against Hepatic Ischemia Reperfusion Injury 注射用内给氧对兔肝缺血再灌注损伤保护作用的实验研究
- Keywords hepatic ischemia damage antioxidant portacaval shunt lipid peroxide reaction superoxide dismutase; 肝缺血损害;抗氧化剂;门腔分流术;脂质过氧化反应;丙二醛;超氧化物歧化酶;
- Methods Focal brain ischemia animal model was used. 方法应用局限性脑缺血动物模型。
- Acute hepatic injury induced by thioacetamide. 用硫代乙酰胺复制急性肝损伤模型。
- Keywords ischemic tolerance hepatic ischemia ethanol gastric gavage; 关键词缺血耐受;肝脏缺血;乙醇;胃饲;
- Right branch of hepatic portal v. 肝门静脉右支。
- Patients with adequate renal and hepatic function. 病人有足够的肾肝功能。
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