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- hTERT gene core promoter hTERT基因核心启动子
- Construction of tumor cell-specific expression vector modulated by human telomerase reserse transcription gene core promoter 人端粒酶逆转录酶基因核心启动子调控的肿瘤细胞特异性表达载体的构建
- The high transcriptional activity of hTERT gene promoter in MCF7 cell indicates its potential utility as a novel candidate for transcriptional targeting of breast cancer. hTERT启动子在乳腺癌MCF7细胞中具有很强的特异性,为进一步开发肿瘤的特异性基因治疗奠定实验基础。
- The HPO gene promoter might represent a novel architecture for core promoters. 这一发现对了解此类基因的转录起始具有一定的指导意义。
- Exogenous hTERT gene transfection could promote the proliferative capacity of hEF. 外源性hTERT基因转染可使hEF增殖能力增强。
- Inactivation of TP53 and activation of c-Myc may play a role in the transcriptive activation of hTERT gene in breast carcinoma. 抑癌基因TP53功能失活及原癌基因c-Myc转录水平上调可能与乳腺癌hTERT基因转录激活有关。
- We analysised the core promoter region with software of Promoter Proscan Version 1.7, the result indicated that the two fragment have core promoter region in 639bp to 389bp before initial code ATG of M0C1 gene. 接着;用Promoter Proscan Version 1.;7软件进行基础启动子分析;发现两段启动子序列的基础启动子区均在在MOC1基因起始密码子ATG前639bp-389bp之间。
- X gene (HBx), enhancer II (Enh2) and basic core promoter (Bcp) of HBV in sera from HCC patients were amplified by nest PCR , and sequenced and then compared with the sequences in Genbank. 对HCC患者血清的HBV的HBx、Enh2与Bcp基因的巢式PCR产物直接测序，与Genbank中已发表序列进行对比分析。
- These findings suggest that hTERT gene expression and telomerase activity may be valuable tumor maker for EOC early diagnosis but its prognostic value needs to be further studied. hTERT表达及端粒酶活性可望作为有价值的肿瘤标志物而用于卵巢癌的早期诊断 ,但其预后价值尚有待于进一步研究。
- Human telomerase reverse transcriptase (hTERT) core promoter 人端粒酶催化亚单位核心启动子
- Objective: To investigate the relationship between HBV basic core promoter(BCP) mutation and serum HBeAg and HBV DNA contents in HBV infected patients. 目的 :研究乙型肝炎病毒 (HBV ) c基因启动子 (BCP)变异与 e抗原及 HBV DNA含量的关系。
- Regulated by the core promoter, transcription of this DNA produces pregenomic and precore messenger RNAs (mRNAs), from which hepatitis Be/c (Hbe/c) antigens and polymerase proteins are translated. 经核心启动子引导，基因转录出前基因mRNA和前C mRNA，并翻译出HBe/c Ag和聚合酶。
- Keywords Hepatitis B virus Core promoter Precore gene Mutation; 肝炎病毒;乙型;C基因启动子;前C基因;变异;
- Study on Expression of hTERT Gene in Human Lung Cancers 端粒酶逆转录酶基因hTERT在肺癌临床诊断中的意义探讨
- telomerase catalytic subunit core promoter hTERT核心启动子
- Keyword： basic core promoter（BCP）of HBV; 关 键 词： 乙型肝炎病毒C基因启动子（BCP）;
- Hepatitis B virus basic core promoter 乙型肝炎病毒核心基因启动子
- Keywords Hepatitis B virus;Core promoter;Precore gene;Mutation;Sequencing; 乙型肝炎病毒;前C基因;C基因启动子;变异;序列分析;
- Construction of recombinant adenovirus of anti-sense RNA targeted to the regulation region of hTERT gene 靶向于端粒酶调控区反义RNA腺病毒的构建
- Detection of telomerase hTERT gene expression in primary lung cancer and exfoliated cell in malignant pleural effusion 原发性肺癌和癌性胸液脱落细胞端粒酶hTERT基因表达的检测
