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- Inguinales superficials hydroncus, the area of the germinal center reduces. 淋巴结周边水肿,淋巴小结生发中心面积减少。
- Beneath the capsule is the paracortical zone with lymphoid follicles having a pale germinal center in which the immune responses are often generated. 被膜下方是有淋巴滤泡的副皮质区,淋巴滤泡有一苍白色的生发中心。
- This is a more pronounced reactive change in a lymph node, with a larger follicle and germinal center containing macrophages. 更明显的淋巴结的反应性改变,有较大的淋巴滤泡和包含巨噬细胞的生发中心。
- Whether E2F1 can be used as a germinal center B cell(GCB)DLBCL marker was also discussed. 同时对转录因子E2F1作为一种新的生发中心B细胞(GCB)型DLBCL的判断指标的可行性进行探讨。
- Pathologic examination:lymph follicle and germinal center activated, while in AZT group showed depletion. 病理学检查,ZY-1组淋巴滤泡和生发中心呈激活状态,为淋巴滤泡增生阶段,而AZT组则滤泡消失,组织萎缩,出现耗竭现象。
- Each follicle contains a germinal center populated by rapidly proliferating B cells and macrophages. 每个滤泡含有一个大量快速增殖的B细胞和吞噬细胞的构成的生发中心。
- The germinal center is surrounded by densely packed small lymphocyte T cells that replicate at a slower rate. 生发中心外周密布增殖低下的小淋巴T细胞。
- At high magnification is seen a lymph node follicle with a germinal center containing larger lymphocytes undergoing activation. At the lower right is the subcapsular sinus. 在高倍镜下可见淋巴滤泡的生发中心有大的活化的淋巴细胞。右下部是被膜下淋巴窦。
- CD154-induced NF-kB nuclear translocation is abnormal in human lupus B lymphocytes with phenotype analogous to germinal center B cells. 与正常人对照相比,SLE外周血B淋巴细胞中CD154诱导NF-资B核转移存在显著异常,类似生发中心表型。
- The periarterial lymphatic sheath in white pulp was thin.There were splenic nodules occasionally, no germinal center was observed. 白髓内动脉周围淋巴鞘薄,偶见脾小结,但无生发中心;
- According to gene expression profile, DLBCL can be divided into germinal center B-cell-like (GCB) and activated B-cell-like (ABC) subgroups. DLBCL可按基因表达分为生发中心B细胞样(GCB)和活化B细胞样(ABC)两组。
- Under the light microscope,white pulp diminished and shrank,germinal center was not clear and there were a little of apoptosis cell. 光镜下白髓数量减少,体积变小,生发中心不明显,高剂量组能见到少量的凋亡细胞;
- Multiple lymphoid aggregates with active germinal centers were also seen. 活跃的生发中心亦可见大量淋巴聚集 。
- At high magnification, the germinal center in this reactive lymph node follicle has prominent macrophages with irregular cellular debris (so-called "tingible body macrophages"). 高倍镜下反应性淋巴结滤泡的生发中心有明显的含不规则细胞碎片的巨噬细胞(称为“易染体巨噬细胞”)。
- In the reactive lymphoid tissues,most of T cells were helper T cells,and in germinal center,mantle zone and paracortex,the Th/i / Ts/c was 11.64,2.56 and 2.04 respectively. 结果表明:在反应性淋巴组织B细胞领域介在的主要是辅助性T细胞,生发中心,帽部及副皮质区、Th/i/Ts/c分别为11.;64,2
- Moreover, we found that E3.5 could recognize the molecule expressed on derma of skin of 38wk-fetus and the germinal center of tonsil tissue by immunohistochemical assay. E3.;5免疫组化鉴定,发现其识别的分子表达于38Wb胎儿皮肤真皮层。 在扁桃体的生发中心亦有表达。
- The splenic specimen had a micronodular pattern, germinal center cytologic composition, and frequent presence of marginal zone-like cells at the periphery of the nodules. 脾脏组织切片镜下肿瘤呈小结节的生长方式,结节由生发中心细胞组成,外周淋巴结的切片中常常见到边缘区细胞样瘤细胞。
- There are many small lymphocytes underneath the epithelia, without formation of germinal centers. 上皮下有很多小淋巴细胞,未见生发中心形成。
- Purpose:To investigate DNA content, DNA ploidy status and the expression of bcl 2 oncoprotein, immunoglobulin light chains(IgL) in follicular germinal center cells (GCCs) of follicular lymphoma (FL) and reactive follicular hyperplasia(RFH). 目的 :观察滤泡性淋巴瘤 (FL)与反应性淋巴滤泡增生 (RFH)中滤泡生发中心细胞 (GCCs)核DNA含量、倍体情况以及bcl 2癌基因蛋白、免球蛋白轻链 (IgL)表达情况 ,探讨它们对于二者鉴别诊断的意义。
- CD40L is transiently expressed on antigen-activated CD4~+ T cells in the form of trimer. It can also be normally expressed on germinal center (GC) B cells or abnormally expressed on B cell-originated malignant cells. CD40L主要以三聚体的形式瞬时表达在抗原活化的CD4~+T细胞表面,也可以瞬时表达在生发中心的B细胞和异位表达在一些B细胞系来源的肿瘤细胞上。