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- LacZ gene was inserted into TK gene deleted transfer vector, the TK /LacZ+ /GTPV-TY mutant was screened. 将LacZ基因表达盒插入TK基因缺失转移载体,筛选TK基因缺失的GTPV-TY突变株。
- A single copy fragment containing cis acting "CACA" box has been identified, which might be the upstream of a new tumor suppressor gene deleted in tumors of the stomach and small intestine. 在胃、小肠肿瘤组织发生缺失突变的片段可能为某一抑癌基因的前半部分 ,即含有启动子成分的调控元件部分CACA盒
- Results: three patients with DAZ gene deleted were found, who are all idiopathic azoospermia with normal karyotype. It accounted for 14.3%(3/21) of idiopathic azoo- spermia, which was in accordance with the public reports (5~16%). 结果：PCR结果共检测出3例DAZ基因缺失，均为核型正常的特发性无精患者，约占特发性无精患者的14.;3%25(3/21)，符合文献报道的5~16%25。
- Objective To analyse the locations and types of gene deletions in Duchenne/Becker muscular dystrophy(DMD/BMD). 目的分析迪谢内/贝克肌营养不良症（DMD/BDM）基因缺失类型及其分布规律。
- Objective To detect dystrophin gene deletion of Duchenne muscular dystrophy (DMD) and make DMD gene diagnosis. 目的探讨Duchenne型肌营养不良症（DMD）患者基因缺失的突变特点并进行基因诊断。
- Results: all of 12 CML cases were bcr/abl gene positive by FISH and 2 cases were associated with ASS gene deletion. 结果:12例CML均检出bcr/abl基因的存在,其中2例伴ASS基因缺失。
- As compared with the FBA, the performance of EFM analysis was superior to FBA in prediction of gene deletion phenotype. 通过EFM预测了基因突变后的酵母细胞生长现象,模拟预测结果和实验结果很好吻合;
- Methods 38 BPH and 18 normal prostatic tissue were detected for MTS1 gene deletion and mutation by means of PCR-SSCP. 方法用PCR-银染SSCP技术检测18例正常前列腺和38例BPH中抑癌基因MTS1各外显子的纯合性缺失和突变。
- Crystallization of Nitrogenase MoFe Protein from a Mutant nifE Deleted Strain of Azotobacter vinelandii 棕色固氮菌缺失nifE的突变种固氮酶钼铁蛋白的结晶
- Conclusion MTS1 gene deletions probably contribute to the tumorigenesis and evolution of primary bladder cancer. 结论MTS1基因缺失与原发性膀胱癌的发生发展有关。
- He was also informed that, due to thalassemia gene deletion or mutation is caused by, but not its genetic transmission. 同时他还得知，地中海贫血由于是基因缺失或突变引起的，因此它遗传但不传染。
- GSTM1 gene deletion might bea risk fac tor for endometriosis in women of Han nationality who are native residents in Gu angdong Province. GSTM1基因缺失可能是广东汉族妇女内异症发病的危险性因素之一。
- Construction of Recombinant PRV PK Gene Deleted Transfer Vector 伪狂犬病毒PK基因缺失转移载体的构建
- The CDKN2 gene deletions were also detected in meningiomas, neurinomas, pituitary adenomas and metastatic carcinomas to a different degree. 脑膜瘤、神经鞘瘤、垂体腺瘤及转移瘤亦存在不同程度CDKN2基因的丢失。
- Conclusion Detection of SMN1 gene deletions with the PCR-enzyme digestion method can be served to diagnose SMA patients accurately and quickly. 结论应用PCR-酶切法检测SMN1基因缺失从而进行SMA患者的基因诊断，具有准确、简便和快速的优点。
- Conclusion Direct identification of SMNT gene deletions could be recommended as an accurate and quick diagnostic method for patients with SMA. 结论应用直接检测SMNT基因缺失的方法可准确快速地诊断中国人SMA患者。
- Keywords Capripoxvirus;Goatpox virus;TK;P32;gene deleted mutant; 羊痘病毒;山羊痘;TK基因;P32基因;基因缺失;突变株;
- Objective To analyse the deletion distribution and the relation of distribution of gene deletions and phenotype in Duchenne/Becker muscular dystrophy (DMD/BMD). 目的了解Duchenne/Becker肌营养不良症（DMD/BMD）基因缺失的分布及其与表型的关系。
- Schmidt EE, Ichimura K, Messerle KR, et al. CDKN2(P16/MTS1) gene deletion or CDK4 amplification occurs in the majority of glioblastomas [J ]. Cancer Res,1994,54(24): 6321. 徐庆中;卢德宏.;脑肿瘤病理分类和诊断工作中的新问题[J]
- Conclusions: PI3K gene deletion or pharmacologic inhibition of PI3K leads to perturbations of critical innate immune responses of the lung to challenge with S. pneumoniae. 结论I3K基因缺失以及药物抑制PI3K干扰了在肺脏抵抗肺炎球菌时具有关键作用的先天免疫反应。
