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- Keywords Capripoxvirus;Goatpox virus;TK;P32;gene deleted mutant; 羊痘病毒;山羊痘;TK基因;P32基因;基因缺失;突变株;
- Detection of quorem sensing pathway and construction of LuxS gene deletion mutants of group B streptococcus [J].J Firse Mil Med Univ/Di Yi Jun Yi Da Xue Xue Bao,2005,25(9):1135-39. B型链球菌数量感应通路测定及 LuxS缺失突变株的构建[J].;第一军医大学学报;2005;25(9):1135-39
- LacZ gene was inserted into TK gene deleted transfer vector, the TK /LacZ+ /GTPV-TY mutant was screened. 将LacZ基因表达盒插入TK基因缺失转移载体,筛选TK基因缺失的GTPV-TY突变株。
- Multiplication and Spread of the rpf C Gene Deletion Mutant of Xanthomonas oryzae pv. oryzac in Susceptible and Resistant Cultivars of Rice 水稻黄单胞菌水稻致病变种rpfC缺失突变体在感病和抗病水稻品种中的繁殖和扩展
- Here we apply the system to the determination of gene function using deletion mutants of yeast (Saccharomyces cerevisiae) and auxotrophic growth experiments. 通过使用人工智能研究中的教训制造出机器人，它能够自动地创造事实假设来解释数据，修正实验以验证其假设，并且能指导实验室的机器人完成试验。
- Objective Construction of S.epidermidis ag r deletion mutant and getting the agr negative mutant and wild-type strain with t he same gene background except agr gene. 目的 构建表皮葡萄球菌agr阴性突变株 ,以期得到除agr基因以外相同遗传背景的突变株与野生株。
- S.epi dermidis agr deletion mutant was successfully constructed, most of sequences o f S.epidermidis 3298-agr were replaced by erythromycin resistance gene. 用同源重组的方法完成表皮葡萄球菌 32 98 agr阴性突变株的构建 ,使agr基因被大部分剔除掉。
- A single copy fragment containing cis acting "CACA" box has been identified, which might be the upstream of a new tumor suppressor gene deleted in tumors of the stomach and small intestine. 在胃、小肠肿瘤组织发生缺失突变的片段可能为某一抑癌基因的前半部分 ,即含有启动子成分的调控元件部分CACA盒
- Results: three patients with DAZ gene deleted were found, who are all idiopathic azoospermia with normal karyotype. It accounted for 14.3%(3/21) of idiopathic azoo- spermia, which was in accordance with the public reports (5~16%). 结果：PCR结果共检测出3例DAZ基因缺失，均为核型正常的特发性无精患者，约占特发性无精患者的14.;3%25(3/21)，符合文献报道的5~16%25。
- These results showed that ANGPTL4 and its deletion mutants can inhibit growth of SMMC-7721 cell in vitro and in vivo, which is through unknown mechanism other than apoptosis. 说明ANGPTL4基因缺失突变体对肝癌SMMC-7721细胞体内、外生长均具有明显抑制作用，但该抑制作用不是通过促进细胞凋亡实现的。
- Objective To analyse the locations and types of gene deletions in Duchenne/Becker muscular dystrophy(DMD/BMD). 目的分析迪谢内/贝克肌营养不良症（DMD/BDM）基因缺失类型及其分布规律。
- Objective To detect dystrophin gene deletion of Duchenne muscular dystrophy (DMD) and make DMD gene diagnosis. 目的探讨Duchenne型肌营养不良症（DMD）患者基因缺失的突变特点并进行基因诊断。
- Results: all of 12 CML cases were bcr/abl gene positive by FISH and 2 cases were associated with ASS gene deletion. 结果:12例CML均检出bcr/abl基因的存在,其中2例伴ASS基因缺失。
- As compared with the FBA, the performance of EFM analysis was superior to FBA in prediction of gene deletion phenotype. 通过EFM预测了基因突变后的酵母细胞生长现象,模拟预测结果和实验结果很好吻合;
- To elucidate the function of HsYif1, we use deletion mutant HsYif1. Over expression of C terminus of HsYif1 induced breakdown of the Golgi apparatus and accumulation of ER, suggestioning HsYif1 may involves in ER to Golgi transport. 因此，我们推断HsYip1A与HsYif1相互作用且决定HsYif1高尔基体定位，并且象酵母中Yif1p-Yip1p复合体功能一样HsYif1-HsYip1A复合体参与内质网到高尔基体运输过程。 虽然HsYif1参与内质网到高尔基体运输过程的分子机理还不清楚，但是我们的研究支持了酵母和人中囊泡运输机制是保守的这样一个观点。
- Methods 38 BPH and 18 normal prostatic tissue were detected for MTS1 gene deletion and mutation by means of PCR-SSCP. 方法用PCR-银染SSCP技术检测18例正常前列腺和38例BPH中抑癌基因MTS1各外显子的纯合性缺失和突变。
- Mutation in the Livin BIR domain greatly enhances its instability and nullifies its binding to Smac/DIABLO, resulting in a reduced anti-apoptosis inhibition, while RING deletion mutant can still interact with Smac/DIABLO. 我们的研究赋予Livin一个新的重要的功能：Livin可以通过泛素-蛋白酶体途径来发挥E3泛素连接酶的功能促进促凋亡因子Smac/DIABLO的泛素化降解，从而在鬼臼乙叉甙诱导的细胞凋亡中更好的发挥其抑凋亡的功能。
- Conclusion MTS1 gene deletions probably contribute to the tumorigenesis and evolution of primary bladder cancer. 结论MTS1基因缺失与原发性膀胱癌的发生发展有关。
- He was also informed that, due to thalassemia gene deletion or mutation is caused by, but not its genetic transmission. 同时他还得知，地中海贫血由于是基因缺失或突变引起的，因此它遗传但不传染。
- GSTM1 gene deletion might bea risk fac tor for endometriosis in women of Han nationality who are native residents in Gu angdong Province. GSTM1基因缺失可能是广东汉族妇女内异症发病的危险性因素之一。
