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- Ganglioside sialidase deficiency 神经节苷唾液酸酶缺乏
- ganglioside sialidase 唾液酸酶
- Objective To investigate the feasibility of reagent kits of sialidase test in the diagnosis of bacterial vaginosis(BV). 目的:探讨唾液酸酶法快速检测试剂盒在细菌性阴道病诊断中的应用价值。
- Objective To investigate the value of the sialidase activity of vaginal secretions in bacterial vaginosis diagnosis. 目的探讨测定阴道分泌物唾液酸酶活性对诊断细菌性阴道病的价值。
- Abstract Objective: To study the protective effect of Ganglioside GM1 on people of severe traumatic brain injury (TBI). 摘要 目的: 探讨单唾液酸四己糖神经节苷脂GM1对重度颅脑外伤脑保护作用。
- Objective:To study the determination of monosialotetrahexosyl ganglioside sodium with the method of HPLC. 目的:研究高效液相层析测定单唾液酸四己糖神经节苷脂钠含量的方法。
- Objective To observe the clinical effect of ganglioside GM1 in different Treatment for acute cerebral infarction. 目的评价不同疗程神经节苷脂GM1(即单唾液酸神经节苷脂)急性期脑梗死的疗效。
- Objective:To observe the protective effect of ganglioside GM1 on hippocampal neurogenesis. 目的:观察神经节苷脂GM1对D-半乳糖致衰老模型小鼠脑海马神经发生的保护作用。
- Objective To explore the protective effect of ganglioside on cerebral ischemia/repeffusion. 目的探讨神经节苷脂对脑缺血再灌注损伤的保护作用。
- Ganglioside(GLS) was a kind of acidic glycolipid on the cell membrane, it had key effect on the devel-opment and regeneration of the nevous system. 神经节苷脂(GLS)是存在于细胞膜表面的一类酸性糖脂,对神经系统的发育再生至关重要,GLS结构复杂,目前只能依赖生物提取方法获得。
- Ganglioside can ease the cerebral tissue lesion during cerebral ischemia/reperfusion by inhibiting the release of glutamic acid. 神经节苷脂通过抑制谷氨酸释放,可减轻脑缺血再灌注期间脑组织损伤。
- The invention changes the polarity of the extracting organic solvent, which makes the ganglioside be released almost fully into the solution. 本发明改变了提取有机溶剂的极性,神经节苷脂几乎全部释放到溶液中。
- Conclusion Ganglioside can ease the cerebral tissue lesion during cerebral ischemia/reperfusion by inhibiting the release of glutamic acid. 结论神经节苷脂通过抑制谷氨酸释放,可减轻脑缺血再灌注期间脑组织损伤。
- FEP method presents good consistency with the experimental result in computing the binding free energy of single GM1 ganglioside to B subunit. 3. 使用全原子分子动力学模拟了霍乱毒素B子单元的结合位点的柔性,并利用FEP(Free Energy Perturbation)的方法计算了单配体与单个B子单元在水溶液中的结合自由能,在定量上较好的与实验结果相符。
- Objective To evaluate long-term effect of ganglioside on neurobehavioral development of neonatal hypoxicischemic encephalopathy (HIE). 摘要目的观察神经节苷脂对中、重度缺氧缺血性脑病(HIE)新生儿神经行为发育的影响。
- Methods Fungus, trichomonad, germs, anaerobic bacteria Gardinerella was detected for sialidase by chemical reaction;Gold colloid method was adopted to detect the antigen of chlamydia trachomatis. 方法真菌、滴虫、各种细菌、厌氧菌、支原体采用体外培养和生化反应的方法进行培养和鉴定,加德纳菌采用化学反应的方法检测唾液酸酶,沙眼衣原体采用金标法检测其抗原。
- Conclusion Ganglioside inhibit the delayed-type hypersensitivity in mice and as well as it inhibit the antigen-presenting capability of epidermal Langerhans cells. 结论神经节苷脂具有抑制小鼠迟发型变态反应,同时说明神经节苷脂可以抑制表皮郎格罕氏细胞抗原提呈作用。
- Conclusion The long period treatment with ganglioside GM1 for acute cerebral infarction could recover the neural function, decrease disability rate and improve the life quality. 结论脑梗死急性期应用长程神经节苷脂GM1治疗能更好地提高神经功能恢复,降低致残率,提高生活质量。
- To understand the mechanism of ganglioside GM 3 effecting on protein kinase C (PKC), the translocation of PKC isoforms in J6 2 cells and the content of diacylglycerol (DAG) was compared between cells treated with GM 3 and control cells. 应用SDS PAGE及Western印迹技术检测神经节苷脂GM3 处理前后人白血病J6 2细胞不同类型PKC在细胞内的转位情况 ;同时利用高效薄板层析技术观察了细胞内DAG含量的变化 ;从而探讨GM3 抑制PKC活性的机制 .
- Keywords sialic acid derivatives;sulfation;sialidase activity; 唾液酸衍生物;硫酸酯化;唾液酸酶活性;