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- Most members of the XRCC genes family participated in several DNA repair pathways, including base excision repair, homologous recombination repair and non-homologous end joining. 目前已鉴定的这一基因家族的多数成员均参与几种重要的DNA修复途径,包括碱基切除修复、同源重组修复和非同源末端重接。
- BACKGROUND & OBJECTIVE: Adenosine diphosphate ribosyltransferase (ADPRT) and X-ray repair cross-complementing 1 (XRCC1) are 2major DNA base excision repair (BER) proteins and act interactively instimulating and executing BER processes. 背景与目的:DNA修复缺陷是肿瘤的遗传易感因素。 二磷酸腺苷核糖转移酶(adenosinediphosphateribosyltransferase,ADPRT)和X线修复交叉互补蛋白1(X-rayrepaircross-complementing1,XRCC1)是碱基切除修复的重要成分。
- Previous studies have shown that sustained ERK1/2 activation elicited by lead acetate (Pb(II)) enhances nucleotide excision repair synthesis and confers anti-cytotoxicity and anti-mutagenicity. 先前研究发现,醋酸铅能藉由持续性活化之ERK1/2讯号而增加核苷酸切除修补能力及降低细胞毒性及基因突变。
- excision repair deficient mutant 剪切突变型
- Nucleotide Excision Repair and Human Disease 核苷酸切除修复和人类疾病
- Excision repair cress-complementation group 1 核苷酸切除修复交叉互补组基因蛋白
- Excision repair cross-complementation group 1 切除修复交叉互补基因1
- Excision repair cross-completion 1 gene 切除修复交叉互补基因1
- Inhibitor of base excision repair 碱基切除修复抑制剂
- excision repair cross-complementing gene 1 (ERCC1) 切除修复交叉互补基因1
- excision repair cross-completion gene 1 修复交叉互补基因1
- Excision repair cross - complementing gene 1 ( ERCCI ) 切除修复交叉互补基因1
- excision repair cross complementing rodent repair deficiency 纠正鼠突变细胞切除修复缺陷
- She turned the chair on its side to repair it. 她把椅子翻转过来修理。
- I have to wait in for the repair man. 我只得在家里等修理工。
- I'm all at sea; I've no idea how to repair cars. 我手足无措,不知道怎样修理汽车。
- John managed to repair his car by himself. 约翰设法独力修理自己的汽车。
- The lorry was damaged beyond hope of repair. 卡车严重损坏,已无修复的希望。
- Dust the repair to prevent adhesion to outer cover. 清整修补处以防与外胎粘连。
- I'm afraid this old radio is beyond repair. 恐怕这台旧收音机不能修了。