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- Objectives To investigate the expression of substance P(SP)and calcitonin gene-related peptide(CGRP)in adenomyosis tissues and in eutopic endometrium. 目的了解神经肽P物质(SP)和降钙素基因相关肽(CGRP)在子宫腺肌病异位内膜和在位内膜中的表达情况。
- Leptin expression was positively correlated to VEGF expression in ectopic endometrium and eutopic endometrium (P< 0.01). 异位内膜、在位内膜中的瘦素与VEGF均呈正相关表达(P<0.;01)。
- The Microvessel density in ectopic endometrium increased compared to that in eutopic endometrium and EMI(P<0.01),but showed no cyclic change . 异位内膜的微血管密度显著大于在位内膜及EMI(P<0.;01);但无周期性变化。
- The morphology and structure of most ectopic endometrium were as same as the eutopic endometrium, though there were less epithelium and stroma in ectopic tissues. 光镜观察见大部分异位子宫内膜形态和结构与在位子宫内膜基本相同，但内膜细胞、间质细胞、腺体，与在位内膜相比较少。
- Because of lower ICAM-1 protein expression in eutopic endometrium with endometriosis, lower of stability and adhesive ability could easily transplant to peritoneal cavity. 子宫内膜异位症患者的子宫内膜中ICAM一1蛋白表达下降，使子宫内膜的稳定性及基底膜的粘附性降低，因而容易“异位”至腹腔内。
- Results: The expression of TNFR1 significantly decreased in ectopic endometrium of endometriosis and adenomyosis than their eutopic endometrium and the control's (P<0.05). 结果：内异症组和腺肌病组异位内膜TNFR1的表达水平显著低于其在位内膜和对照组(P<0.;05)；
- The estradiol expression in ectopic endometrium was slightly higher than those in eutopic endometrium of adenomyosis,but no statistical significance was found (P>0.05). 异位宫内膜雌二醇的表达略高于原位宫内膜;但无统计学意义(P>0.;05)。
- Compared with eutopic endometrium and EMI,the VEGF staining intensity in ectopic endometrium increased significantly (P<0.01), but showed no cyclic change. 异位内膜腺上皮细胞VEGF表达强度较在位内膜及EMI显著增加(P<0.;01);但无周期性变化。
- The expressions of HGF and c-met gene are correlated with the pathogenesis of endometriosis, which is preceded by eventful changes in the biological be-havior of the eutopic endometrium. HGF、c-met基因和蛋白表达与子宫内膜异位症发病机制相关,在位内膜性质的改变可能是子宫内膜异位症发病机制的关键环节。
- Human eutopic endometrium tissues from patients with endometriosis were collected to isolate endometrial stromal cells for culture. 收集子宫内膜异位症患者的在位子宫内膜组织分离培养子宫内膜间质细胞；
- The purity of stromal cells was more than 95%. [Conclusion] The isolation and culture of eutopic endometrial stromal cells can serve as an in vitro experimental modle. 间质细胞的纯度达95%25以上。结论在位子宫内膜间质细胞可在体外成功得到分离、培养，并可作为子宫腺肌病在体外研究的细胞模型。
- Eutopic endometrial stromal cell 异位内膜间质细胞
- Changes of Distribution and Number of NK Cells of Ectopic and Eutopic Endometrium in Endometriosis 子宫内膜异位症中在位和异位内膜自然杀伤细胞的分布及数量变化
- Expressions of Bcl-2,estrogen receptor(ER)and progesterone receptor(PR) in endometriosis and eutopic endometrium Bcl-2基因、雌激素受体和孕酮受体在子宫内膜的表达
- Keywords Chemokine receptor;Eutopic endometrium;Endometriotic tissue;RT-PCR;Endometriosis; 趋化因子受体;在位内膜;异位灶;RT-PCR;子宫内膜异位症;
- Keywords endometriosis;eutopic endometrium;levonorgestrel-releasing intrauterine system;proliferation;apoptosis; 子宫内膜异位症;在位内膜;左炔诺孕酮宫内节育系统;增殖;凋亡;
- Expression of vascular endothelial growth factor in the peritoneal fluid and eutopic endometrium of patients with endometriosis 子宫内膜异位症患者腹腔液和在位子宫内膜血管内皮生长因子表达的研究
- Keywords Neiyikangfu suppository;rectal administration;endometriosis;ectopic and eutopic endometrium;sexual hormone receptors;apoptosis;immunochemical; 关键词内异康复栓;直肠给药;子宫内膜异位症;异位和在位内膜;性激素受体;细胞凋亡;免疫组化;
