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- Recently, a fat emulsion containing LCT and medium-chain triglycerides (MCT) in a physical or chemical mixture have been developed for intravenous use. 含中链甘油三酯的脂肪乳剂,由于其结构、生化特征,具有氧化快而完全,较少依赖肉毒碱转运等优点,目前已普遍应用于临床营养支持中。
- TG,SB,ALT and PTA of the two groups were investigated before and after the therapy of fat emulsion. 观察治疗前后其血清甘油三脂(TG)、胆红素(SB)、谷丙转氨酶(ALT)、凝血酶原活动度(PTA)和治疗后病死率,两组进行比较。
- Abstract BACKGROUND AND AIM: To study the teratogenic effect of fat emulsion of seal oil in rats. 摘要 背景与目的: 探讨海狗油脂肪乳对大鼠致畸毒性作用。
- RESULTS After it was homogenized for several times,the fine homogeneous fat emulsion would be obtain... 结论:安全地输注给上千例病人,表明本制剂工艺具有科学性和实用性。
- Etomidate fat emulsion as a new form of medication is attracting more attention from researchers. 新剂型依托咪酯脂肪乳剂的出现使其重新引起人们的重视。
- Drug loaded nanoparticle is a new type of peroral drug delivery system with tremendous advantages over traditional dosage forms. 综述近年来口服载药纳米粒的有关研究进展,着重从制备方法、表面修饰、药物释放及应用几个方面进行介绍。
- The membrane filtration technique adding polysorbate 80 was used in the sterility test of fat emulsion for intravenous injection. 静脉滴注用脂肪乳剂无菌检查采用加吐温80的薄膜过滤法,可以代替直接接种法,不需要再转接种,并且便于结果判断。
- Other two kinds of fat emulsion that were composed of 10%/20% cholesterol and 15%/30% lard separately had no increasing effects. 胆固醇10%25和15%25、猪油20%25和30%25比例的脂肪乳剂配方升高血脂水平作用不明显。
- MATERIALS: Forty-five male Sprague Dawley (SD) rats were used to establish animal models of hyperlipoidemia by intragastrically with fat emulsion. 材料:选用SD雄性成年大鼠45只,均灌胃脂肪乳剂建立高脂血症动物模型。
- Objective To evaluate the stability of total parenteral nutrition (TPN), especially the fat emulsion, when added with alany-glutamine. 目的观察丙氨酰-谷氨酰胺对全合一肠外营养液稳定性尤其是脂肪乳剂稳定性的影响。
- When the temperature was lower than the LCST, although DgP could not form micelle, stable ILM could be formed with the drug load content as high as 45.2%. 当温度低于LCST时;虽然纯的DgP在水溶液中不会形成胶束;但是稳定的ILM依然可以形成;而且其最大载药量达到45.;2%25。
- RESULTS After it was homogenized for several times,the fine homogeneous fat emulsion would be obtained which could be easily absorbed by patient. 结果:通过数次匀化可获得粒子小、均匀性好、人体易于吸收的脂肪乳剂。
- The progress of drug loaded intravenous lipid emulsions in enhancing drug solubility and stability,reducing side effects, sustained release, targeted delivery and gene therapy is introduced. 介绍了静脉注射用脂肪乳剂在提高药物溶解度和稳定性、减轻药物不良反应、缓释、靶向给药和基因治疗等方面的研究进展。
- Results: Therapeutic intravenous emulsions improved the drug targeting and slow releasing action,which enlarged the application range of fat emulsions. 结果:药用静脉注射乳剂提高了药物的靶向性和缓释作用,增加了脂肪乳剂的应用范围。
- Methods Modeled the mice fatty liver by high fat emulsion,compareing with DBGT tablet, and observe the effects of Ganzhixiao Mixture on mice liver pathology histology. 方法以高脂乳剂塑造小鼠肝高脂的脂肪肝模型,以东宝肝泰片为阳性对照,并观测肝脂消合剂对小鼠的肝组织病理的影响。
- OBJECTIVE To study the preparation of aciclovir loaded albumin microspheres (ACV BSA MS) and evaluate its morphology,drug loading and release in vitro. 目的 优化阿昔洛韦白蛋白微球的制备工艺 ,并对其形态学性质、载药量、体外释药进行考察。
- Abstract:Objective To discuss the biurea method for determination of total protein in serum of fat emulsion specimens with double reagents on the automated biochemical analyzer. 摘要:目的探讨双试剂双缩脲法在全自动生化仪中直接测定脂肪乳浊标本血清总蛋白。
- Results: Therapeutic intravenous emulsions improved the drug targeting and slow releasing action, which enlarged the application range of fat emulsions. 结果:药用静脉注射乳剂提高了药物的靶向性和缓释作用,增加了脂肪乳剂的应用范围。
- Major applicate as analgesics, emulsifier and dispersant in fat emulsion agent, anti-tumor agent, penicillin additive, the natural activity component phospholipid complex and artificial blood etc. 主要应用于脂肪乳类制剂、抗肿瘤制剂、青霉素添加剂、天然活性成份磷脂复合物、人造血等中作为镇痛剂、乳化剂、分散剂。
- And pH gradient active drug loading method was employed to improve the DEE of INT liposome. 通过pH梯度主动载药法提高脂质体的包封率;