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- Parkinson's disease is a common and disabling disorder of movement owing to dopaminergic denervation of the striatum. 帕金森氏病是一种常见的由于纹状体除多巴胺能神经支配的运动异常疾病。
- dopaminergic denervation 去多巴胺能神经
- Central denervation was performed in the spinal cord or sacral nerve roots. 中枢性去神经施行于脊髓及骶神经根。
- The dopaminergic receptors were measured with the radio-ligand binding assay. 采用同位素标记法测定受体变化;
- Thus, PD is much more than degeneration of the dopaminergic nigrostriatal system. 因此,PD并不仅仅是多巴胺黑质纹状体系统的变性。
- Lesioning and psychopharmacological studies suggest a wide range of behavioral functions for ascending midbrain dopaminergic systems. 损伤和精神药理学的研究提示:中脑多巴胺能系统参与广泛的行为学功能。
- Effects of 5 MPa Heliox Pressure Anaesthesia on Dopaminergic Pathway: An In Vivo Neurochemical and Receptor Study. 5MPa的氦氧混合气压力麻醉对多巴胺能神经传导的影响:活体中影响神经系统的化学物质研究、及受体研究。
- Autoimmune-induced damage of the midbrain dopaminergic system in lupus-prone mice. 免疫诱导的中脑多巴安系统损伤。
- Most of these models rely on a partial denervation of the limb of the animal by ligating a selected nerve. 绝大多数的这些模型依赖于结扎所选择的神经使动物肢体部分去神经。
- However, it is still unclear how this denervation perverts normal functioning to cause slowing of voluntary movements. 然而,仍然不清楚去神经支配是怎么导致正常功能反常,随意运动减慢的。
- Blocks agonist or antagonist activity at adenosine, adrenergic, dopaminergic, muscarinic, opioid and P2Y receptors. 阻碍腺苷酸、肾上腺素、毒蕈碱、类鸦片活性肽和P2Y的受体的拮抗剂或对抗剂活性。
- The SK3 channel was overexpressed in skeletal muscles after denervation and in patients with myotonic dystrophy(DM). 使去神经支配和肌强直营养不良患者骨骼肌SK3表达显著上调。
- Symptomatic treatment with dopaminergic and anticholinergic medications remains the mainstay at the present time. 现阶段的处置以药物的症状治疗为主。
- Critical illness polyneuropathy (CIP) causes acute axonal injury in peripheral nerves and muscle denervation. 重症多神经病变为急性轴突神经病变,使骨骼肌去神经化,发生率的报导从22-82%25都有。
- Continuous dopaminergic drug deliery is an unmet medical need in adanced Parkinson's disease. 晚期帕金森患者中持续多巴胺能药物应用不能满足治疗需要。
- Electrophysiologic testing demonstrated active denervation restricted to the diaphragm.Long-term recovery was poor. 电生理检查证实活化的去神经支配限制了膈肌,患者的远期恢复较差。
- Objective To study the apoptosis effects and the mechanisms of action by homocysteine on dopaminergic neurons. 目的:研究同型半胱氨酸能否通过内质网应激的途径诱导多巴胺能神经元凋亡。
- Abstract: Objective To study the toxicity of exogenous dopamine(DA) in dopaminergic neurons. 摘 要: 目的研究外源性多巴胺对多巴胺能神经元的毒性作用。
- However, cauterization and denervation of the sex organs and even castration were sometimes also deemed necessary. 然而,性器官腐蚀法和支配神经阻断法以及阉割法有时竟然也被认为是必须的治疗措施。
- Management consists of dopaminergic drug replacement, supportive measures, and treatment of complications. 治疗措施包括多巴胺替代疗法、支持疗法和治疗并发症。
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