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- It also indicates that TBA-DNA adducts can be partly eliminated by DNA repair. 这表明，TBA与小鼠肝/肺DNA加合物在小鼠体内能得到一定的修复。
- Cancer genetics, somatic mutagenesis, DNA repair, genomics and molecular medicine. 肿瘤发生的遗传机制；体细胞突变的发生机制；DNA修复，基因组学与分子医学。
- It is caused by an inherited weakness in one gene that controls DNA repair in other genes. 这是因为某种基因比较脆弱，使得DNA无法修复其他基因。
- At the same time, cerebral ischemia can activate a complex network of DNA repair tocounteract neuronal DNA damage. 然而缺血在导致DNA损伤的同时，还激活自身的DNA修复系统。
- We calculated lymphocyte post irradiation viability ratio to detect the defection of DNA repair after DN... 即基因修复缺陷可能是帕金森病发病机制的重要环节。
- Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1. 聚（ADP -核糖）依赖的DNA修复调节的染色质重塑酶ALC1。
- DNA repair pathways can enable tumor cells to survive DNA damage induced by anti-tumor drugs such as alkylating agents. DNA损伤修复能够使肿瘤细胞耐受化疗药物造成的DNA损伤而存活,因此,调节某种特殊的DNA修复路径可以增强化疗药物的疗效。
- P63 may also co-ordinate DNA repair in eggs with fewer than three breaks, says Dr McKeon. P63可能在卵细胞三次分裂以前对DNA的修复起到协调作用，McKeon称。
- The activity of DNA repair enzyme reduction may involve the mechanism of apoptotic neuron death after ischemia/reperfusion. （2）大鼠脑缺血/再灌注后缺血区神经元凋亡与神经元DNA修复酶活性下降有关。
- PCNA also plays an important role in the DNA repair of neuron,gliocyte proliferation,and cell apoptosis after cerebral ischemia. 脑缺血后出现神经元细胞DNA修复、胶质细胞增生以及细胞凋亡等,PCNA在其中发挥了重要作用,因此受到人们的广泛关注。
- Therefore, modulating specific DNA repair pathways might prove efficacious when used in combination with DNA-damaging chemotherapeutic drugs. 另外,有些DNA修复路径在一些肿瘤细胞中是失活的。
- Some DNA repair genes are irreversibly damaged by smoking, and smoking also switched off genes that help combat lung cancer development. 而吸烟将不可逆的破坏一些DNA修复基因，并关闭一些对抗肺癌的基因。
- Gene expression is highly regulated and interconnected to processes like mRNP processing, mRNA export as well as to DNA repair and replication. 专有名词的识别在资讯萃取的步骤中扮演著重要的角色，文件中资讯的描述，皆由专有名词引述出资讯的所在。
- In addition, alterations in DNA repair pathways that arise during tumour development can make some cancer cells reliant on a reduced set of DNA repair pathways for survival. 此外，在肿瘤发展过程中出现的DNA修复通路的转变可以使一些癌细胞依赖于DNA修复通路的减少而得以生存。
- In a word, the FANCD2 activity adjusted exquisitely by ubiquitination and/or deubiquitination in vivo may co-regulate the FA pathway involving in variant DNA repair pathway. 机体很可能在不同信号通路对FANCD2泛素化/去泛素化的精细调节下，调控FA途径参与不同的DNA修复过程。
- Most members of the XRCC genes family participated in several DNA repair pathways, including base excision repair, homologous recombination repair and non-homologous end joining. 目前已鉴定的这一基因家族的多数成员均参与几种重要的DNA修复途径,包括碱基切除修复、同源重组修复和非同源末端重接。
- Histone lysine methylation has important functions in many biological processes that include gene expression,X-chromosome inactivation,gene imprinting and DNA repair. 组蛋白赖氨酸甲基化作为共价修饰的一种在基因表达调控、X染色体失活、基因组印迹、DNA修补等生物学过程中起重要作用。
- One line of eidence supporting the connection is that defects in certain genes needed for DNA repair produce maladies that mimic those of accelerated aging. 支持这种关系的证据是需要修复的特定基因的损伤产生疾病例如加速衰老。
- PCNA also plays an important role in the DNA repair of neuron,gliocyte proliferation,and cell apoptosis after cerebral ischemia.So it attracts more attention. 脑缺血后出现神经元细胞DNA修复、胶质细胞增生以及细胞凋亡等，PCNA在其中发挥了重要作用，因此受到人们的广泛关注。
- The main mechanism of cisplatin is tumor cells death by damaging the DNA.The resistance to cisplatin is associated with the cell's increased ability of DNA repair. 顺铂的主要药理机制是损伤细胞DNA,肿瘤细胞DNA修复能力增强则会导致其对顺铂耐药。
