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- Objective To establish a simple animal model and the cytotoxic T cell(CTL) detecting system for the studies of the effects of CTL on HCV infection. 目的建立一个简便易行的动物模型及细胞毒性T细胞(CTL)检测体系,为HCV感染中CTL作用研究奠定理论基础。
- These T cells are sometimes referred to as cytotoxic T cells. 这些T细胞有时被称为细胞毒性T细胞。
- The former are brought about by T lymphocytes termed cytotoxic T cells, that seek out and kill virally-infected host cells or cancer cells. 前者是由称之为毒T细胞的T淋巴球,去搜寻并杀灭受到感染的细胞或癌细胞。
- According to their function can be divided into three subgroups: T helper cells, inhibition of cytotoxic T cells and T cells. 按其功能可分为三个亚群:辅助性T细胞、抑制性T细胞和细胞毒性T细胞。
- Interleukins are proteins produced by lymphocytes in order to activate other lymphocytes such as cytotoxic T cells and NK cells. 白介素是由淋巴细胞产生的,用以激活其他淋巴细胞(如细胞毒性T细胞和自然杀伤细胞)的多种蛋白质。
- The binding of antigenic peptide sequences to major histocompatibility complex(MHC) molecules is a prerequisite for stimulation of cytotoxic T cell responses. 抗原多肽序列与主要组织相容性复合体(MHC)分子的结合是引起T细胞免疫应答的先决条件。
- One of the most important actions of T cells is to lyse the cells expressing specific antigens. Most cells with such cytotoxic activity are CD8~+ T cells called cytotoxic T lymphocytes (CTLs). 具有这种细胞毒性作用的T细胞的表面抗原大部分是CD_8阳性,被称为细胞毒性T淋巴细胞(cytotoxic T lymphocytes,CTLs)。
- Flow cytometry analysis revealed that there was increasing number of CD8(superscript +) cytotoxic T cells with positive lymphotactin staining with the severity degree of inflammation. 进而我们探究了流式细胞仪的分析结果显 示具有lymphotactin抗体呈色的CD8+毒杀型T细胞数量亦随著发炎状态恶化而增加。
- But NIAID pulled the plug on its trial after an examination of the data from a phase II study showed that fewer than 30 percent of the volunteers generated cytotoxic T cells against HIV. 但是NIAID在审视了该疫苗第二阶段试验的数据,发现只有不到30%25的受试者体内产生对抗HIV的杀手细胞,于是他们决定终止试验。
- DNA vaccine of HCMVpp65 could induce the cellular immunity of the host. It expressed by the mixed immunization of cytotoxic T cell(Tc)1 and Tc2,in addition to proliferation effects of the spleen T lymphocytes. HCMVpp65核酸疫苗接种可诱导宿主的细胞免疫反应,倾向于表现为细胞毒性T细胞(Tc)1和Tc2的混合应答以及脾脏T细胞的增殖效应。
- cytotoxic T cells(CTL) 细胞毒性T淋巴细胞
- ObjectiveTo study ultrastructural changes of BGC 823 gastric cancer cells due to the killing effects of the specific cytotoxic T lymphocytes(CTL). 目的研究特异性细胞毒T淋巴细胞(cytotoxicTlymphocyte,CTL)杀伤胃癌细胞BGC?823的超微结构变化。
- BACKGROUND Cell-mediated immunity dominate the antitumor immune response, antigen-specific cytotoxic T lymphocytes(CTL) are the major effector cells. 背景知识 肿瘤免疫以细胞免疫为主,抗原特异性细胞毒性 T淋巴细胞(CytOtoXIC T lymphocyte, CTL)是重要的效应细胞之一。
- AIM: To explore the mechanism and conditions of activating the killing effect of cytotoxic T lymphocyte (CTL) by dendritic cells (DC) sensitized by soluble antigen of lung cancer. 目的:通过肺癌的可溶性抗原致敏的树突状细胞(DC)激活细胞毒性T细胞(CTL)的杀伤作用各个环节的研究;初步探讨其作用机制及影响条件.
- 3.Enhanced cytotoxic activity of cytotoxic T cells and NK cells. 3.;加强毒T细胞和NK细胞的细胞毒素活性。
- Purpose:To investigate the proliferation of cytotoxic T lymphocytes(CTL) induced by superantigen SEA and their anti-tumor effects on EJ bladder carcinoma cells in vitro. 目的:研究超抗原金黄色葡萄球菌肠毒素A(SEA)对淋巴细胞激活、增殖的作用及对E-J膀胱肿瘤细胞的抑癌效应。
- With adjuvant of CpG or the cell wall skeleton of coryne bacterium parvum ( CB Pw) , we analyzed each groups T-cell proliferation and cytotoxic T lymphocyte ( CTL) response. 以CpG基序作为佐剂,以CBPw作为对照佐剂,测定各组的T细胞增殖试验和CTL活性。
- Objective:Using apoptotic tumor cells-loaded dendritic cells (DCs) to activate the antigen-specific cytotoxic T lymphocytes (CTL) and observe their effects against lung cancer in vivo and in vitro. 目的用凋亡肿瘤细胞致敏的树突状细胞(dendritic cells,DCs)激发肿瘤抗原特异性的细胞毒T细胞(cytotoxic Tlymphocytes,CTL)活性,观察其体内外抗肺癌的特性。
- Objective To explore the specific cytotoxic T lymphocyte(CTL) response induced by DC pulsed with tumor lysates from multiple myeloma patients. 目的研究负载肿瘤抗原的树突细胞能否诱导特异性细胞毒T淋巴细胞反应。
- Cytotoxic T lymphocyte (CTL) responses、activated by HLA antigen presentation、are implicated in the control of HIV replication. 人类白血球抗原激发的T淋巴细胞与HIV病毒的复制有关连。