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- Objective To prepare the cucurbitacin B loaded poly(lactic-co-glycollic acid) nanospheres(CuB-PLGA-NS). 目的制备葫芦素B聚乳酸羟基乙酸纳米球。
- Objective To study the distribution of cucurbitacin B loaded PLGA nanospheres in mice. 目的 研究葫芦素B聚乳酸-羟基乙酸毫微球小鼠体内分布。
- Cucurbitacin B sc 0.1mg/kg or 0.2mg/kg obviously inhibited the expression of Fas and FasL, and number of apoptotic cells in dose-dependent manner. sc葫芦素B 0 .;1mg/kg和 0 2mg/kg可使Fas和FasL的表达明显降低并呈剂量依赖性。
- Methods After admistration to mice by iv, HPLC was used to determine the concentration of cucurbitacin B of plasma, heart, liver, spleen, lung, kidney and brain respectively. 方法 小鼠尾静脉给药， HPLC法测定葫芦素B在小鼠血浆、心、肝、脾、肺、肾、脑中的浓度。
- Conclusion Cucurbitacin B loaded PLGA nanospheres show passive targeting to liver.The established HPLC method can be used for cucurbitacin B biodistribution study. 结论 葫芦素B聚乳酸-羟基乙酸毫微球可实现肝脏被动靶向，所建立的HPLC法用于葫芦素B的体内分布研究，结果良好。
- Keywords capillary zone electrophoresis;Pedicellus Melo;cucurbitacin B; 毛细管区带电泳;甜瓜蒂;葫芦素B;
- Keywords Cucurbitacin B;alcohol;jaundice;liver injury;lipid peroxidation; 葫芦素B;酒精;黄疸;脂质过氧化;
- Keywords cucurbitacin B;human serum albumin nanoparticle;HPLC;assay; 葫芦素B;人血清白蛋白纳米粒;高效液相色谱法;含量测定;
- In English, b, p, m and w are bilabials. 英语中的b、p、m、w为双唇音。
- Keywords cucurbitacin B;poly（lactic-co-glycollic acid）;nanospheres;solvent-evaporation method; 葫芦素B;聚乳酸-羟基乙酸;纳米球;溶剂挥发法;
- C comes after B in the alphabet. 在字母表中C接在B后面。
- The "b" in "comb" is not sounded. comb这个词里的"b"是不发音的。
- The old woman does not know from A to B. 这位老太太一字不识。
- B comes before C in the alphabet. B在字母表里排在C之前。
- Keywords cucurbitacin B;self-microemulsifying drug delivery system（SMEDDS）;formulation optimization;pseudo-ternary phase diagram; 葫芦素B;自微乳化药物传递系统;处方优化;假三元相图;
- Line A is four times the length of line B. 线条
- Many letters in the alphabet such as b, c, d, etc are consonants. 字母表中的许多字母像b，c，d，等等都是辅音字母。
- cucurbitacin B laurate 葫芦素B月桂酸酯
- B, c, d, f, etc. are consonants. B,c,d,f等都是辅音字母。
- cucurbitacin B 葫芦素B
