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- Keywords X-linked spondyloepiphyseal dysplasia tarda;SEDL gene;acceptor splice site mutation;cryptic splice site activation; 连锁迟发性脊椎骨骺发育不良;SEDL基因;剪接受体突变;潜在剪接位点激活;
- cryptic splicing site 隐蔽剪接部位
- cryptic splice site 隐蔽剪接位点
- Exon 7 splicing mechanism stems from the loss of TRIM5 intron 6 within the first 3 'splice site of the G / T mutation. 外显子7剪接丢失机制源于TRIM5第6内含子内3’剪接位点的G/T突变。
- By masking the mutation, Kole was able to shift splicing back to the normal splice site and restore production of functional hemoglobin. 柯尔的寡核苷酸可以遮盖突变序列，让剪接体找回正常剪接位，而制造出功能俱全的血红素。
- In this paper, grouped weight matrix (GWM) method is proposed for splice site recognition. 摘要提出识别剪切位点的分组权重矩阵方法。
- The experimental results show that the HMM identification system acquires higher rate in the splice site identification than popular machine learning techniques. 实验结果表明，该识别系统在用于剪接位点的识别中较常用的机器学习方法获得了更高的识别率。
- Antisense oligonucleotides could be delivered into cells to mask either a specific splice site or some other regulatory sequence, thereby shifting the splicing activity to another site. 这种寡核苷酸送入细胞后，可以遮盖住某个特定的剪接位或调节序列，而将剪接活动转移到其他位置。
- In this study, we built a system to detect splice sites in the genomic DNA and to generate all possible isoforms. 其中，雷射振镜主要用于控制雷射行进方向，以及调整雷射焦距，是影响雷射焦点准确性的重要设备。
- In this thesis, we use both Hidden Markov Model (HMM) and Weight Array Model (WAM) to predict the splice sites. 本文基于隐Markov模型(HMM)和权重阵列模型(WAM)两种方法来预测剪接位点。
- Alternative splicing can divide splice sites into alternative donor sites,constitutive donor sites,alternative acceptor sites and constitutive acceptor sites. 选择性剪切的出现把剪切位点分为选择性供体位点、组成性供体位点、选择性受体位点和组成性受体位点。
- The protein has no hydrophobic transmembrane anchor region at the C-terminus and has 19 exons and 18 introns, and splice sites conform to GT/AG rule. 结构分析无C末端疏水跨膜结构，含有19个外显子和18个内含子，剪切信号符合GT/AG规则。
- Considering the specialties of the splice sites, the method to encode the DNA sequences, WAM and the HMM themselves are modified to achieve better results. 在使用这两种方法时，针对剪接位点本身的特点，本文对HMM本身和WAM本身都做了一定的改进。
- GROUPED WEIGHT MATRIX FOR SPLICE SITE RECOGNITION 识别剪切位点的分组权重矩阵方法
- orientation-negative splice site 负向拼接位置
- non-competitive splice site pair 非竞争性剪接位点对
- cryptic splicing 隐蔽剪接
- The monument was moved bodily to a new site. 纪念碑整个迁到一个新场址。
- Is it safe to site the power station here? 在这建造发电厂安全吗？
- He can splice together the broken ends of ropes quickly. 他能把断了的绳子头快速接起来。
