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- Keywords methotrexate;intrathecally injection;chronic neuropathic pain; 甲氨蝶呤;鞘内注射;慢性病理性疼痛;
- Comparison of the Analgesic Effects of Electroacupuncture at Different Acupoints in Chronic Neuropathic Pain Rats 不同穴位电针治疗大鼠慢性神经源性痛的疗效比较
- Keywords Radixange sinensis Chronic neuropathic pain Analgesia Immunohistoche-mistry Astrocyte; 当归;注射液;坐骨神经痛;镇痛;星形胶质细胞;免疫组织化学;
- Comparison of the Therapeutic Effects of Electroacupuncture with Different Interval for Treatment of Chronic Neuropathic Pain in Rats 不同频度电针治疗大鼠慢性神经源性痛的疗效比较
- Effect of intrathecal ketamine on the calcium ion concentration in the spinal dorsal root ganglion neurons in a rat model of chronic neuropathic pain 鞘内注射氯胺酮对神经痛大鼠背根神经节细胞内钙含量的影响
- ESTABLISHMENT OF AN IMMORTALIZED RAT ASTROCYTE STRAIN EXPRESSING ENKEPHALIN REGULATED BY DOXYCYCLINE AND ITS ANALGESIC EFFECT ON RAT CHRONIC NEUROPATHIC PAIN 强力霉素诱导表达脑啡肽细胞株的构建及其对慢性神经痛大鼠的镇痛作用
- chronic neuropathic pain 慢性神经病理性痛
- Methods:SD rat CCI (chronic constriction injury) hyperalgesia model was used as the neuropathic pain model, and hyperalgesia score employed as the sign of neuropathic pain. 方法:采用轻微结扎一侧大鼠坐骨神经的神经痛模型,以光热辐射引起的大鼠双下肢抬脚潜伏期的差值作为神经痛的指标(痛敏分数)。
- Chronic pain due to brachial plexus avulsion (BPA) is a kind of refractory neuropathic pain, yet there is a lack of knowledge regarding underlying brain activity. 臂丛神经撕脱伤后慢性疼痛是一种临床上顽固性神经病理性疼痛。
- Gabapentin Acts within the Locus Coeruleus to Alleviate Neuropathic Pain. 加巴喷丁作用于蓝斑核可减轻神经性疼痛。
- This study suggests new aenues to manage neuropathic pain in this setting. 这项研究对治疗神经性疼痛提供了一条新途径。”
- It is used not only in treatment of depression, but also in treatment of stress urinary incontinence and diabetic peripheral neuropathic pain. 目前发现不仅可以治疗抑郁症,还可用于治疗压力性尿失禁与糖尿病周围神经病性疼痛。
- BACKGROUND: Many animal models can be used to study the underlying pathophysiological mechanisms of neuropathic pain. 背景:很多动物模型被用来研究神经性疼痛的基础病理生理学机制。
- However, neurontin (gabapentin) and other anti-epileptic drug may reduce both spasms and neuropathic pain. 然而,加巴(加巴喷丁)和其他抗癫痫药物可减少痉挛和神经性疼痛。
- There were no significant functional changes in any patients and no neuropathic pain. 患者没有出现明显功能改变和神经性疼痛。
- Objective: Mutual prodrugs of gabapentin and pergabalin were synthesized for relieving neuropathic pain. 目的:合成具有抗神经病理性疼痛的加巴喷丁和普瑞巴林的互联体前药化合物。
- Neuropathic pain refers to pain that originates from pathology of the nervous system. 神经病理痛是指由中枢或外周神经系统损伤或疾病引起的疼痛综合征。
- Drugs to treat neuropathic pain are usually of some benefit, including gabapentin, carbamazepine, and amitriptyline. 加巴喷丁、卡马西平、阿米替林等药物治疗神经性疼痛疗效常较好。
- Sodium channel of dorsal root ganglion (DRG) plays an important role in the mechanisms of neuropathic pain. 摘要脊髓背根神经节的钠通道与神经性疼痛的形成有密切的关系。
- Our findings show that this may cause neuroinflammation in the dorsal root ganglion and neuropathic pain. 我们的研究显示这可能导致背角神经节的神经炎症和神经病理性痛。