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- Soft tissue sarcomas are a highly heterogeneous and polygenous group of tumor, and characterized by specific chromosome translocations and corresponding fusion genes. 软组织肉瘤是一种起源不同、形态学复杂多样的恶性肿瘤,其诊断和鉴别诊断一直是病理学家们的主要挑战之一。
- About non-Robertsonian Wheat-rye chromosome translocation lines. 类型小黑麦易位系的研究。
- She was diagnosed as having an unbalanced chromosome translocation, severe mental retardation and epilepsy. 当时她被诊断为患有一种染色体易位错乱症，临床表现为严重的智力迟钝及癫痫症状。
- Using genomic PCR and sequencing, FLT3/ITD mutation with or without chromosome translocation were examined in AML patients. 采用PCR联合序列检测伴有或不伴有染色体易位的急性髓性白血病患者FLT3基因突变情况。
- Objective To explore genes involved in chronic myeloid leukemia (CML) with t(3;21) (q26;q22) chromosome translocation in blastic crisis. 目的探讨慢性粒细胞白血病(CML)急性髓系白血病(AML)变伴 t(3;21)(q26;q22)的受累基因。
- The AML1?ETO fusion proteins generated by chromosome translocation of t (8; 21) lead frequently to pathogenesis of acute myeloid leukemia (AML). t(8;21)染色体易位是导致急性髓系白血病的最常见的发病机制;AML1 ETO是t(8;21)易位所产生的融合基因.
- The variance componentof cross and backcross generations of quantitative character controlled by multigenes is studied on condition of chromosome translocation. 研究了染色体易位情况下,多基因控制的数量性状杂交及回交世代的方差组成。
- AIM: To explore the relationship of FLT3/internal tandem duplication (ITD) mutation and chromosome translocation with acute myeloid leukaemia (AML) prognosis. 目的:探讨FLT3跨膜区内部串联重复(FLT3/internal tandem duplication,FLT3/ITD)突变和染色体易位与急性髓性白血病预后的关系。
- CML is caused by a reciprocal chromosome translocation between chromosome 9 and 22, resulting in the short Philadelphia (Ph) chromosome carrying the BCR-ABL (Breakpoint Cluster Region-Abelson Leukaemia) oncogene. CML的分子遗传学特征是费城染色体(Philadelphia chromosome，Ph)的出现。
- The prognosis is relatively poor in FLT3/ITD mutation patients with chromosome translocation. FLT3/ITD mutation with chromosome translocation may be an important marker for poor prognosis of AML. 伴有染色体易位且FLT3/ITD突变的急性髓性白血病患者预后较差,染色体易位和FLT3/ITD突变可以作为其预后不良的重要标志。
- AML 1 gene abnormalities, including both chromosome translocation and mutation (point mutation, insertion, deletion mutation, et al), which lead to the lost of transcript activation, are general in acute leukemia. 在急性白血病中常见AML1基因结构异常，包括平衡易位及突变(如点突变、插入或缺失突变等)，导致AML1的转录活性丧失，提示此基因功能缺失在急性白血病的发生及发展中起着重要作用。
- Objective To study the genetic effect of balanced chromosomal translocation. 摘要目的研究染色体平衡易位的遗传效应。
- Chromosomal translocation is a kind of common chromosomal abnormality. 染色体易位是常见的染色体结构异常。
- Chromosome breaks may also lead to inversions and translocations. 染色体破裂也可能引起倒位与易位。
- The second process involves another type of genetic accident called a chromosomal translocation. 第二种过程涉及到称为染色体移位的另一类基因故障。
- reciprocal chromosome translocation 染色体相互易位
- The position that a given gene occupies on a chromosome. 基因座在一条染色体上某种给定基因所占的位置
- The carriers with chromosomal translocation could have more chance of normal pregnancy with the help of fluorescence in situ hybridization (FISH). 应用荧光原位杂交技术,染色体易位携带者可在胚胎植入前遗传学诊断的帮助下增加正常妊娠的机会。
- chromosome translocations 染色体易位
- A chromosome composed primarily of heterochromatin. 异染色体主要由异染色质组成的染色体
