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- Objective To investigate the relationship between the results of sperm chromatin structure assay (SCSA) and the outcome of unexplained abortion and infertility. 目的探讨女方不明原因流产和不明原因不孕与其配偶精子染色质性状之间的关系;
- Keywords Sperm chromatin structure assay;Flow cytometry;DNA injury; 精子染色质结构分析;流式细胞术;DNA损伤;
- chromatin structure assay 染色质结构分析
- sperm chromatin structure assay 精子染色质结构分析
- VIN3 is involved in initiating the modification of FLC chromatin structure. VIN3与FLC染色质结构修饰的起始有关。
- Histones, as basic components of nucleosome, are essential to chromatin structure and function. 摘要组蛋白作为核小体的基本组分，是染色质的结构和功能必需的。
- Abstract : Histones, as basic components of nucleosome , are essential to chromatin structure and function. 摘要 ： 组蛋白作为核小体的基本组分，是染色质的结构和功能必需的。
- "We may need two types of chemicals, one to loosen the chromatin structure, and one to reprogram. 她说:“我们也许需要两种类型的化学物质,一种疏松染色质结构;
- Histone modifications such as lysine methylation affect chromatin structure and gene expression. 组蛋白修饰（如赖胺酸残迹的甲基化）能影响染色质结构和基因表达。
- Histones, as the basic components of nucleosome, are essential to chromatin structure and function. 组蛋白作为核小体的基本组分，是染色质的结构和功能必需的。
- Sperm membrane integrity, Mitochondrial function and chromatin structure integrity can embody sperm quality. 质膜完整性、线粒体功能、染色质结构完整性等可体现精子的质量，但测定方法较繁琐。
- Genome activation occurs in a stepwise manner.Changes in nuclear structure,chromatin structure,and cytoplasmic content regulate the period of EGA. 胚胎基因组的形成和激活在早期胚胎的发育中起关键作用,主要包括胚胎细胞核的形成和胚胎细胞质由转录抑制状态向激活状态转变。
- Covalent modifications of histone tails play a key role in the regulation of chromatin structure and control of transcriptional activity. 染色体组蛋白的共价修饰在调节染色体结构,控制基因的转录等方面发挥重要的作用。
- Epigenetic phenomena are stable inheritance of gene expression patterns controlled by higher order chromatin structure that depends on covalent modifications of DNA and histones. 表观遗传现象是由于DNA和组蛋白的化学修饰而导致的染色质的空间结构变化而引起的相对稳定基因表达状态的继承。
- Overall, our results suggest that a significant part of individual expression variation in yeast arises from evolution of a small number of chromatin structure modifiers. 研究人员总结认为，酵母进化过程中存在的个体表达差异，一部分原因是小数量染色体结构重塑。
- Lamin proteins are thought to determine the size and shape of cell nuclei and to be involved in nuclear stability,chromatin structure and gene expression. 型核纤层蛋白决定细胞核的大小及形状,与细胞核的稳定性、染色质结构以及基因表达有关。
- Heterochromatin also flanks the centromere in the central region of the chromosome, the chromatin structure that plays a crucial role in chromosome segregation during cell diision. 异染色质也经常出现在染色体中间着丝点的附近。着丝点在细胞复制时的染色体分离中起着重要作用。
- We will discuss the importance of chromatin structure in contemporary modeling, and review recent research results on the relationship between chromatin structure and transcriptional regulation. 我们会讨论在当代的模型化里染色质结构的重要性，并且温习在染色质结构和转录调控之间关系上，当前的研究工作成果。
- At these pre-decision stages, apparently opposing chromatin structures may coexist on a gene locus but resolve in subsequent stages into exclusively activating or silencing structures (Fig. 1). 在前决定阶段里，明显的反向的染色质结构可能共同存在基因位点，但是在后来的阶段分解成专有的具有活性或沉默的结构。
- Chromatin Structure and Gene Activation 染色质结构与基因活化
