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- The development of tumor involves in many factors, such as activating of oncogen, invalidating of cancer suppressor genes and abnormal expressing of apoptosis genes. 肿瘤的发生和发展涉及原癌基因的激活、抑癌基因的失活、凋亡相关基因的异常表达等,是涉及多基因、多因素的过程。
- cancer suppressor gene 抑癌基因
- Recent evidence suggests that Tob could be a tumor suppressor gene in lung cancer. 最近的研究表明:在肺癌的发病机制中Tob可能为抑癌基因。
- Basal cell neus syndrome is caused by a tumor suppressor gene, called PTCH, located on chromosome 9. Mutations in this gene may increase the risk of oarian cancer. 谢谢楼主给大家发这么典型的片子;基底细胞痣综合症的临床资料比较缺乏;这对大家讲学和经验积累很有帮助.;多谢;新年快乐!
- BRCA1 inactivates a tumor suppressor gene known as PTEN. BRCA1能够使人体内一种叫PTEN的肿瘤抑制基因失去活性。
- Objective:To study the effects of tumor suppressor gene mda-7/IL-24 on the ovarian cancer cell line A2780 and drug-resistant cell line A2780/DDP. 目的:探讨抑癌基因mda-7/IL-24对卵巢癌细胞株A2780和耐药株A2780/ DDP耐药性的影响。
- DCC gene is an important tumor suppressor gene, and its alterations play a role in thepathogenesis and progression of colorectal cancer. DCC基因是一个在结直肠肿瘤发生发展中起重要作用的抑癌基因，该基因的异常与结直肠癌发生发展有关。
- The evidence from cancer cell lines and primary tumor tissues suggests that WWOX is a tumor suppressor gene and that its inactivation contributes to cancer devel. 原发肿瘤组织及细胞系的研究证明该基因为肿瘤抑制基因,其失活可能导致肿瘤的发生,基因敲除实验证实了上述假设。
- As RB gene is the first identified tumor suppressor gene, the finding has reolutionalized our understanding of cancer pathogenesis, so this huge interest is understandable. 由于RB基因是首先发现的抑癌基因，使我们对于肿瘤的发病机理有了全新的认识，其重大意义是可以理解的。
- Objective: To study the expression of the tumor suppressor gene RASSF1A in breast cancer, and the correlation between the expression and the promoter hypermethylation of RASSF1A. 摘要目的：研究抑癌基因RASSF1A在乳癌组织中的表达情况及与RASSF1A基因启动子甲基化的关系。
- BACKGROUND & OBJECTIVE: Full-length form of spleen tyrosine kinase [Syk(L)] is a tumor suppressor gene in breast cancer, which may translocate into cell nucleus and act as a transcriptional repressor. 背景与目的:全长型脾脏酪氨酸激酶[full-length form of spleen tyrosine kinase,Syk(L)]在乳腺癌中具有抑癌功能,可移位到细胞核内,作为转录抑制因子调节基因的转录。
- A study of tumor suppressor genes on chromosome 9 in glioblastomas. 胶质母细胞瘤9号染色体肿瘤抑制基因的研究。
- Conclusion PTEN tumor suppressor gene may be involved in the development of nasopharyngeal carcinoma, 5, 8 of its first exon in the development of nasopharyngeal cancer may not afford a key role. 结论抑癌基因PTEN可能参与鼻咽癌的发生发展，其第5、8外显子在鼻咽癌的发生发展中可能不起关键作用。
- Objective: To study the expressions of pro-onc and tumor suppressor genes in gastric cancer by cDNA expression array. 目的:从基因水平了解正常胃和胃癌组织原癌基因和抑癌基因表达的分子机制。
- Objective To investigate the expression of tumor suppressor gene PTEN in breast carcinomas and its significance. 摘要目的研究肿瘤抑制基因PTEN在乳腺癌组织中的表达及临床意义。
- Objective To investigate expression and significance of tumor suppressor gene PTEN in esophageal carcinoma. 目的探讨抑癌基因PTEN在食管癌中的表达及临床意义。
- The expression of genes that inhibit cancer deelopment, so-called tumor suppressor genes, is often lost in tumor cells. 抑制癌症发生的基因即所谓的肿瘤抑制基因，其表达常在肿瘤细胞中缺失。
- Rb correlates with tumorigenesis closely, and is an important tumor suppressor gene. Rb与人类多种肿瘤发生关系密切，是一种重要的肿瘤抑制基因.
- Now, the theory of oncogenes activity and tumor suppressor genes (TSG) inhibition can lead to cancer have been accepted. 目前，人们已经普遍接受了癌基因的激活和抑癌基因的失活可导致癌症发生的理论。
- The advances in the study of tumor suppressor genes in gliomas were reviewed. 作者就目前在脑胶质瘤中研究较多的抑癌基因的进展作了综述。
