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- camptothecin methylamide 喜树碱甲酰胺
- Effects of Camptothecin, Amsacrine and Vinblastine on the cell cycle of lymphocytic or myelogenous leukemia cells. 喜树碱、胺苯吖啶、长春花碱对淋巴细胞性和髓样白血病细胞周期的影响。
- Topotecan(TPT)is a semisynthetic analogue of the natural product camptothecin that exerts antineoplastic activity. Topotecan(TPT)是类似天然抗癌药物喜树碱的半合成新药。
- Objective To review some delivery systems for camptothecin and its analogs in recent years. 目的对喜树碱类药物的一些特殊传递系统进行综述。
- At present,our main products are 10-Hydroxy camptothecin,7-Ethyl-10-Hydroxy camptothecin,cefotiam,eplerenone and so on. 目前，公司产品主要有10-羟基喜树碱、7-乙基-10-羟基喜树碱、头孢替安、依普利酮等产品。
- Preparation of 10-hydroxy camptothecin (HPT) by camptothecin (CPT) through oxidation and photoactivation was studied. 文中采用半合成法对10羟基喜树碱的制备进行了研究,以喜树碱为原料,通过氧化和光化两步反应得到HPT初产品。
- This paper summarized the synthesis and antitumor activity of camptothecin and its derivatives in recent years. 该文总结了近年来喜树碱及其衍生物的合成与活性研究方面的最新进展。
- Conclusion Two modified form of synergy can effectively solve the poor solubility of camptothecin and the mot... 结论两种修饰方式的协同作用可以有效的解决天然喜树碱溶解性差,母体毒副作用大的缺点。
- The concentration of camptothecin was determined in different tissues of Camptotheca acuminata seedling. 摘要测定不同生长期喜树苗各器官中喜树碱的含量。
- Method Liposome, polymer carrier, microsphere and other delivery systems for camptothecin were reviewed in detail. 目的对喜树碱类药物的一些特殊传递系统进行综述。
- This papar summarized modifying molecular structure and relation between structure to activity of camptothecin. 本文对结构修饰和构效关系做一简要综述。
- The accumulation of camptothecin and 10-hydrocamptothecin presented evident relativity in the different growth stages. 在生长过程中,喜树叶片中喜树碱和10-羟基喜树碱的含量变化呈现出明显的相关性。
- Camptothecin was isolated in 1966, but its use was hampered by its poor water solubility. 喜树碱早在1966年就已经被分离出来,由于水溶性差而阻碍了对它的使用。
- Title： Effects of Camptothecin,Amsacrine and Vinblastine on the cell cycle of lymphocytic or myelogenous leukemia cells. 关键词：喜树碱;胺苯吖啶;长春花碱;细胞周期;脱噬作用
- Result The problems of camptothecin such as solubility,stability and side effects could be solved by special delivery methods and strategies. 结果通过一些特殊的传递方法与策略,可以解决喜树碱类药物所存在的溶解度、稳定性、毒性和不良反应等问题。
- Conclusion As the development and maturation of some novel drug delivery system, camptothecin will be a kind of potential anticancer drugs. 结论随着新的药物传递系统的不断成熟与发展,喜树碱类药物将是十分有潜力的一类抗肿瘤药物。
- Camptothecin is a crude anti-cancer drug.The recent progress in totalsynthesis of(S)-camptothecin was reviewed with 14 references. 本文对天然抗肿瘤药物喜树碱近几年的合成研究进展作了一综述,参考文献14篇。
- Conclusion The effect and WBC change of hydroxy camptothecin on chronotherapy in EAC mice had chrono-effect and changes. 结论 拓喜（羟基喜树碱）除了对小鼠艾氏腹水癌移植瘤抑制作用有明显的时辰差异外，对WBC的也有时辰的变化。
- Results Suspension culture cells grew well in MS medium and cell homogeneity and camptothecin content were superior to those in other media. 结果悬浮培养细胞在MS培养基中细胞生长良好,细胞分散性和喜树碱积累优于在其他培养基中。
- Objective To observe the therapeutic effect of combining camptothecin ointment with pevisone cream in the treatment of patients with chronic eczema and neurodermatitis. 目的观察喜树碱软膏与派瑞松霜联合应用治疗慢性湿疹和神经性皮炎的疗效。
