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- AIM:To study the effect of CD73 on breast cancer cell line MB-MDA-231 adhesion to extracellular matrix. 目的:探讨CD73对乳腺癌细胞MB-MDA-231与细胞外基质黏附的影响及其机制。
- CDA-II could reduce the growth speed, proliferation ability and bcl-2 expression and induce apoptosis of breast cancer cell lines. CDA-II可减缓两株乳腺癌细胞的生长和增殖能力,诱导乳腺癌细胞凋亡,减少乳腺癌细胞bcl-2表达。
- Human breast cancer cell lines MCF 7 and MCF 7/Adr can transcribe VEGF C mRNA and translate corresponding protein in their cytoplasm. 人乳腺癌细胞株MCF 7及其耐药株MCF 7/Adr细胞能够转录VEGF CmRNA并在其细胞浆中翻译合成相应的蛋白。
- The study has shown the anti-HER2 effect of fractions of phenolic compounds directly extracted from extra virgin olive oil in breast cancer cell lines. 研究展示了直接从特级初榨橄榄油中萃取的酚类化合物片段在乳腺癌细胞系中的抗HER2效果。
- A precursor of itamin E has been shown to be effectie against breast cancer cell lines which oer-express human epidermal growth factor receptor (HER2). 现有的研究已表明,维生素E原能够有效地对抗那些过度表达人类表皮生长因子受体(HER2)的乳腺癌细胞系。
- Background and purpose:Most breast cancer cell lines were derived from malignant pleural fluid or other tissues that metastasized from breast carcinoma. 背景与目的:乳腺癌细胞系大部分来源于乳腺癌转移所致的胸水或非原始乳腺癌组织来源,与真正的乳腺癌的生物学性状有很大差异。
- Objective To investigate the effect of drug resistance by arsenic trioxide (As 2O 3) and its possible mechanism in human breast cancer cell line MCF 7/ADM. 目的 探讨三氧化二砷 (As2 O3 )对人乳腺癌MCF 7/ADM细胞耐药性的逆转作用及其相关机制。
- Methods Estrogen receptor(ER)-positive MCF-7 human breast cancer cell line was treated by tamoxifen (TAM) or adriamycin(ADM) alone ,or TAM and ADM in combination. 目的 探讨三苯氧胺(tamoxifen,TAM)和阿霉素(adriamycin,ADM)联合应用对乳腺癌细胞MCF-7(ER+)生长和凋亡的影响。
- The infl uence of recombinant adenovirus on the growth of breast cancer cell line MCF7 was stu died. Results show that the recombinant adenovirus can inhibit the growth of MCF7. 获得的重组病毒粒子作用于人乳腺癌细胞系MCF7,初步表明重组腺病毒能抑制MCF7的生长。
- Objective: To investigate the effects of three-dimensional microstructures of silicon and glass substrates on the growth of breast cancer cell line MCF-7. 目的:研究硅和玻璃片基上的三维微结构对乳腺癌MCF-7细胞生长的影响。
- Experimental Design: CD55-high and CD55-low population was sorted from breast cancer cell line, injected into immunodeficient mice, and the resultant tumor volume was measured. 实验设计:从乳腺癌细胞系中分离出CD55高表达和低表达的细胞群体,注射入免疫缺陷的大鼠体内,测量产生的肿瘤体积。
- Methods MTT assay was wed to detect the effects of heparin on growth of human breast cancer cell line MDA-MB-231,enzyme linked sorbent assay (ELSA) were employed to detect the expressions of Hyase,HA and CEA of 8 human breast cancer cell lines. 方法用MTT法测定肝素对人乳腺癌细胞株MDA-MB-231生长的影响; 酶联吸附法测定8株人乳腺癌细胞培养上清液中Hyase、HA和CEA的表达。
- Methods: D6 mRNAs in 9 cases of human breast cancer cell lines, 4 cases of breast cancer tissues, and normal human spleen tissues were analyzed by semi-quantitative RT-PCR. The difference of D6 gene expression was further confirmed by real-time PCR. 方法采用半定量RT-PCR法检测D6mRNA在人乳腺癌细胞株、乳腺癌组织以及正常脾组织中的表达,并用实时荧光定量-PCR进一步验证其在细胞中表达的差异;
- It was showed that in breast cancer cell line,the chemosensitivity sequence for single drug was EPI>CDDP>MMC >5FU,the chemosensitivity sequence for combined drug was 5FU+EPI>5FU+CDDP>EPI+CDDP>EPI+MMC>MMC+CDDP >5FU+MMC. 资料显示,乳腺癌细胞株化疗敏感性顺序:EPI>CDDP>MMC>5FU; 联合用药的敏感性顺序:5FU+EPI>5FU+CD-DP>EPI+CDDP>EPI+MMC>MMC+CDDP>5FU+MMC。
- Objective To clone apoptosis related genes induced by all trans retinoic acid (ATRA) from human breast cancer cell line MCF 7, and to analyze the association between the cloned genes and apoptosis. 目的 克隆人乳腺癌MCF 7肿瘤细胞凋亡相关的基因 ,分析所克隆基因与凋亡的关系。
- Objective:The study was designed to examine the expressions of vascular endothelial growth factor C(VEGF C) mRNA and protein in human breast cancer cell line MCF 7 and drug resistant cell line MCF 7/Adr. 目的 :检测血管内皮生长因子C(vascularendothelialgrowthfactorC ,VEGF C)mRNA和蛋白在人乳腺癌细胞株MCF 7及其耐药株MCF 7/Adr中的定位、定性表达。
- AIM: It is to investigate that apoptosis of MDA-MB-435 cell, a human breast cancer cell line, was induced by recombinant retroviral vector mediated CED-4 gene of cadherin 5 N terminal and its apoptosis mechanism. 目的:研究粘附素5 N 端CED-4(cadherin extracellular domain-4)基因经重组逆转录病毒介导转染人乳腺癌细胞MDA-MB-435 及其诱导MDA-MB-435 细胞凋亡的分子调控机制。
- METHODS They were compared that the rates of apoptosis in human breast cancer cell line MCF 7/ADR which were reistant to adriamycin(Dox) and their parental sensitive cell line MCF 7 induced by Dox in the presence or absence of TTD. 方法MDR细胞株MCF-7/Adr与其相应的敏感株MCF-7进行对比研究。 比较粉防己碱对阿霉素(Dox)诱导MDR细胞及其相应的敏感株的凋亡作用。
- METHODS: Human breast cancer cell line MCF 7, human gastric cancer cell line BGC 823, human prostate cancer cell line DU 145, and human colon cancer cell line HT 29 were treated with 5 Aza CdR. 方法:用5-Aza-CdR作用人乳腺癌细胞系MCF-7、人胃癌细胞系BGC-823、人的前列腺癌细胞系DU-145和人结肠癌细胞系HT-29。
- Cao J G,Tang X Q,Zhou H,et al.Reveral of Multidrug Resistance by neferine in adriamycin resistant human breast cancer cell line MCF7/ ADM[J].The Chinese睪erman J Clin Oncol,2004,3(2):9396. 唐小卿;曹建国;冯鉴强.;甲基莲心碱对耐阿霉素人乳腺癌细胞凋亡抗性的影响[J]