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- Lipid raft is a special kind of detergent resistant microdomain floating on the cell plasma membrane, in which the key components of T cell activation signaling pathway locate. 脂筏是一种膜脂双层内含有的特殊微区,T细胞膜表面参与T细胞激活的各种关键信号分子都定位于脂筏。
- Keywords lipid raft;sphingomyelin;HPTLC; 脂筏;鞘磷脂;高效薄层层析;
- RhoA was also located in the lipid rafts of brain and cerebellar granule cells as well as cortical neurons. RhoA 也可分布于成年大鼠大脑、小脑颗粒细胞以及皮质神经元的Lipid Rafts 上。
- Experiments showed the effect of metal ions on the shape, size and surface structure of lipid rafts. 实验表明金属离子对脂筏的形成、尺度和表面形貌都有影响。
- Lipid rafts or caveolae carry out their specialized role in signal transduction, cellular protein movement and cholesterol homeostasis. 脂筏或小窝与生物信号传导、细胞蛋白转运和胆固醇平衡有关。
- Lipid rafts are liquid-ordered membrane microdomains with a unique protein and lipid composition found on the plasma membrane of most mammalian cells. 摘要脂筏是细胞膜内由特殊脂质与蛋白质构成的微域。
- The important functions that lipid rafts play in infectious diseases are indicative of their potential application in fighting against these diseases. 脂筏在感染性疾病中的重要作用提示，它很有可能成为扭转这些疾病发生和进程以及治疗这些疾病的重要入手点。
- CONCLUSION: A small reduction in membrane cholesterol enlarges or increases lipid rafts concomitant with phosphorylation of intracellular proteins. 结论：质膜胆固醇微量减少能使脂筏成分伴随着细胞内蛋白的磷酸化扩大或增加。
- As specialized lipid rafts, caveolae are present on many types of mammalian cells, particularly on endothelial cells, adipocytes and smooth muscle cells. 膜窖是脂筏的一种特殊类型,在哺乳动物的内皮细胞、脂肪细胞及平滑肌细胞质膜上分布尤为丰富。
- Lipid rafts and caveolae are found to be essential for insulin-like growth factor (IGF)-1 receptor signaling during 3T3-L1 preadipocyte differentiation induction. 目前的研究表明膜上受体在介导跨膜信号转导时，通常是在细胞质膜上的脂质筏和质膜微囊结构中进行的。
- The sailors got away from the wrecked ship on a raft. 水手们乘救生筏离开失事的船。
- Lipid rafts play important roles in many biological processes including transmembrane signal transduction, endocytosis, lipid and protein sorting, and so on. 脂质筏参与包括跨膜信号转导、物质内吞、脂质及蛋白定向分选在内的多种重要细胞生物学过程。
- Two principal proteins modifications are found in lipid rafts: one is covalent binding to glycosyl-phosphatidylinositol (GPI), the other is myristoylization. 分布于脂筏的分子主要有两种形式的蛋白修饰：与糖基磷脂酰肌醇(GPI)相连，或被肉豆蔻酸酰化/软脂酸酯酰化。
- The raft was floating gently down the river. 筏子顺河水缓缓漂流。
- Many people get away from the wrecked ship on a raft. 许多人乘救生艇离开遇难的船。
- They floated down the river on a raft. 他们乘着木筏向河的下游漂去。
- A whole raft of people came for drinks. 许多人来喝酒。
- He met with a raft of troubles last year. 去年,他遇到了许多麻烦。
- The raft was buoyed up by empty petrol cans. 这木筏依靠空汽油桶的浮力漂浮。
- We found the shipwrecked sailors on a raft. 我们在一个木筏子上找到了失事船只的船员。
