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- Methods The loss of heterozygosity (LOH)of YNZ22, APC, MCC and DCC genes was examined by PCR RFLP technique in 60 IM cases. 方法 應用PCR?RFLP法檢測了60 例腸化生組織中YNZ22、APC 、MCC、DCC基因雜合性缺失現象。
- Objective To evaluate the loss of heterozygosity (LOH) and microsatellite instability (MSI) in the early diagnosis of bladder cancer. 目的探討染色體微衛星不穩定性(MSI)及雜合性丟失(LOH)在膀胱癌早期診斷中的意義。
- Thirteen (2/15) percent of acute leukemia patients had loss of heterozygosity (LOH);the rate was higher than that in other leukemia types. 15例急性白血病中2例有LOH，比其他白血病發生率高。
- It was found that loss of heterozygosity(LOH) at MCC,LOH of DCC and LOH of YNZ22 loci were detected in 34.8%,36.0%and 43.3% of informative cases,respectively. 大腸癌MCC基因LOH率為34.;8%25； DCC基因為36
- Objective: To explore the role of the loss of heterozygosity (LOH) of DCC gene in the occurrence and development of primary hepatocellular cancer (HCC). 目的：了解結腸癌缺失基因（DCC基因）在原發肝癌發生髮展中的作用。
- Objective: To investigate the relationship between the loss of heterozygosity(LOH) of MCC, DCC or YNZ22 loci and the development and progression of colorectal carcinoma. 目的：研究MCC、DCC基因和YNZ22位點雜合性丟失（LOH）與大腸癌發生髮展的關係。
- Objective To study the relationship between the loss of heterozygosity (LOH) at APC and MCC genetic loci and the incidence and development of esophageal carcinoma. 目的研究APC/MCC基因雜合性缺失(LOH)與食管癌發生髮展的關係。
- Objective: To detect the status of loss of heterozygosity (LOH) on chromosome 8 in prostate carcinoma and high grade prostatic intraepithelial neoplasia (PIN). 目的:分析原發性前列腺癌及高級別前列腺上皮內腫瘤(PIN)8號染色體等位基因雜合性缺失(LOH)並探討其意義。
- Relative survival(RS%),relative suspension growth(RSG%),mutation frequency at tk locus and percentages of slow growth mutant(SC%) were detected and loss of heterozygosity(LOH) of mutants were analyzed. 檢測細胞相對存活率(RS%25)、相對懸浮增長率(RTG%25)、tk位點突變頻率(M F)和緩慢生長集落的百分比(SC%25),同時對突變集落tk位點雜合性丟失(LOH)進行分析。
- Objective To explore the relationship of the telomere length to microsatellite instability (MSI) and to loss of heterozygosity (LOH) of APC, MCC and DCC genes in gastric carcinomas. 目的 探討端粒長度與微衛星不穩定 (MSI)和APC MCC及DCC基因雜合丟失 (LOH)的關係。
- Methods 20 loci on chromosome 9 were examined to detect loss of heterozygosity(LOH) in 21 cases of glioblastoma by PCR based microsatellite polymorphism analy-ses, in which fluorescence-labeled primers and Perkin Elmer 377 DNA Sequencer were applied. 方法 應用聚合酶鏈反應（PCR）方法，採用熒游標記引物和377型DNA序列自動分析儀，分析21例 GBM 9號染色體上 20個微衛星多態性標記的LOH。
- Study on loss of heterozygosity of DCC in primary gastric carcinoma. 原發性胃癌中DCC抑癌基因雜合性丟失的研究
- A study on the loss of heterozygosity at 17p13.3 and abnormal expression of p53 protein in gastric carcinoma. 胃癌組織17p13.;3雜合性丟失及p53蛋白異常表達的研究
- Loss of heterozygosity at different chromosomes in pa-tients with breast cancer. 乳腺癌病人不同染色體位點上雜合缺失的研究
- In addition, 36.4% (8/22) of prostatic tumor tissues had loss of heterozygosity of GNMT gene. 此外，攝護腺癌組織GNMT基因有36.;4%25 (8/22)異合性喪失的情形；
- In conclusion, the Lanyu pig is a unique breed without gene introgression from exotic pig breeds, but it had sustained loss of heterozygosity. 綜合以上之結果，推論保種蘭嶼豬與以上6個台灣外來豬種間發生基因交流之可能性低為一獨特之族群，但此族群可能因近親配種致其基因多型性流失。
- METHODS: Twenty-three fresh resection samples of colorectal carcinomas were studied by the polymerase chain reaction (PCR) to detect the loss of heterozygosity of DCC. 方法:採用聚合酶鏈反應方法(polymerasechainreaction,PCR)對23例結直腸癌組織新鮮標本DCC基因雜合性缺失(lossofheterozygosity,LOH)進行研究。
- Microsatellite analysis showed that both loss of heterozygosity and microsatellite instability of FHIT gene existed in laryngeal carcinoma and the former was more common. 微衛星多態分析表明，FHIT基因在喉癌中既存在雜合性丟失，又存在微衛星不穩定現象，但以前者為主。
- Associations between compartment-specific TP53 status, loss of heterozygosity or allelic imbalance, and clinical and pathological characteristics were computed. 協會之間的隔間具體tp53地位，雜合性缺失或等位基因不平衡現象更加嚴重，臨床及病理特徵的計算機。
- Cong WM,Wu MC.Features of microsatellite instability and loss of heterozygosity of intrahepatic cholangiocarcinoma[J].Zhonghua Zhongliu Zazhi(Chin J Oncol),2002,24(2):141. [24]叢文銘;吳孟超.;肝內膽管癌的微衛星不穩定性和雜合性缺失特點[J]
