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- Phospholipase A2(PLA2)is a family of enzymes which catalyzes the hydrolysis of the special ester bond of phospholipids. 磷脂酶A2是一大類能催化水解磷脂特定酯鍵的酶,與哺乳動物神經系統存在密切的關係。
- Objective:To demonstrate the role of phospholipase A2 activity (PLA2) on the apoptosis of neutrophiles. 目的:探討磷脂酶A2(PLA2)活性的變化對中性粒細胞凋亡的影響。
- The hydrolysis of lecithin by phospholipase A2 was firstly studied in vesicle solution and the influence of relevant parameters was investigated. 摘要首次在泡囊水溶液中研究磷脂酶A2催化水解卵磷脂並考察了各種因素對該反應的影響。
- Objective To explore the protective effects of dexamethasone(DXM)-the inhibitor of phospholipase A2(PLA2) on endotoxemia animals. 目的研究磷脂酶A2(PLA2)抑製劑地塞米松(DXM)對內毒素血症動物的保護效應。
- Therefore, phospholipase A2 activity will directly lead to the PC concentration variances in the bile and result in the formation of gallstones. 故磷脂酶A2活性的改變會直接導致卵磷脂濃度發生變化,從而影響膽結石的形成。
- The animals were sacrificed at 24. 48. 72hour under sterile circumstance. The blood samples were collected for analysis of serum amylase(AMY). phospholipase A2 (PLA2). 三組動物分別於術后24、48、72小時無菌條件下活殺取材,腹主動脈取血,送檢血澱粉酶(AMY)、磷脂酶A_2(PLA_2)、白介素-6(IL-6)。
- Objective To investigate the effect of polymorphonuclear elastase (PMNE) and phospholipase A2(PLA2) on the acute lung injury in severe acute pancreatitis (SAP). 目的應用大鼠牛磺膽酸鈉重症胰腺炎模型探討粒細胞彈力蛋白酶(PMNE)和磷脂酶A2(PLA2)在重症胰腺炎(SAP)併發急性肺組織損傷中的作用。
- Retkova D H, Monchilova-Pankova AB, Kounanovks, et al.Effect of liver plasma membrane fluidity to endogenous phospholipase A2 activity [J]. Biochem, 1987,69(6): 1251. 商品.;運動中脂質過氧化物對紅細胞膜結構和功能的影響[J]
- Cytosolic phospholipase A2 involved in the signal pathway of induction of apoptosis in human umbilical vein endothelial cells by minimally modified low-density lipoprotein. 胞漿型磷脂酶A2介導弱氧化修飾低密度脂蛋白誘導的人臍靜脈內皮細胞凋亡。
- Either the A(C15S) chain and B(C55S) chain alone or in combination can not exhibit the phospholipase A2 activity or synaptosome binding activity of b-Bgt. 純化的A(C15S)鏈與B(C55S)單獨或混和測試時均無明顯Phospholipase A2 的酵素活性,同時也無法與Synaptosome 結合。
- Abstract : The effect of calcium ion on the conformation of neutral phospholipase A2(NPLA2) from the venom of Agkistrodon kalys palls was studied by fluorescence spectroscopy. 摘要 : 用熒光光譜方法研究了鈣離子對江浙蝮蛇毒中性磷脂酶A2(簡稱NPLA2)構象的影響。
- The activity of phospholipase A2 (PLA2) and content of Evans blue in tissue and infusing fiuid of rats lung were measured by microtitration. In experiment the tested rats were located under condition simulated 4 000m altitude to 48 hrs. 採用滿足法測定了在模擬高原4000m停留48h大鼠肺組織及肺灌洗液的磷脂酶A2活性和伊文思藍含量的變化。
- Conclusion:Results suggested that the neutrophile apoptosis may be promoted by phospholipase A2 activation,but this process may not be related with PAF,one of the important metabolites of PLA2. 結論:結果表明PLA2激活可促進中性粒細胞凋亡過程,但該過程可能同PLA2的代謝產物血小板激活因子的直接作用無關。
- Objective:To study the concomitant effect of bone morphogenetic protein(BMP) on the activity of the phospholipase A2 (PLA2),which were injected into the lumbar nucleus pulposus of the rabbits to enhance the intervertebral fusion. 目的:探討腰椎間盤髓核內注射骨形態發生蛋白(BMP)對磷脂酶A2(PLA2)活性的影響。
- Objective To investigate the effect of lidocaine and anisodamine on the alternations of serum amylase,phospholipase A2(PLA2),endotoxin and pathology in acute necrotizing pancreatitis(ANP) rats. 目的探討利多卡因及山莨菪鹼對急性壞死性胰腺炎(ANP)大鼠血澱粉酶、磷脂酶A2、內毒素及其病理學變化的影響。
- Sa G et al. Activation of cytosolic phospholipase A2 by basic fibroblast growth factor via a42Pmitogen activated protein kinase-dependent phosphovylation pathway in endothelial cells[J]. J Biol Chem, 1995,270:2360. 周蘭、常英姿、邱宗萌;等.;鹼性成纖維細胞因子對缺血/再灌注大鼠心臟的保護作用[J]
- Pretreatment of ECs with phospholipase A2 inhibitor p-bromophenacyl-bromide or cahnodulin antagonist chlorpromazine and aildum ion chelate EGTA obviously decreased H2O2 induced increment of EC-PMN adhesion. 磷脂酶A_2抑製劑對溴苯醯基溴、鈣調蛋白抑製劑氯丙嗪和鈣離子螯合劑EGTA預處理EC都能顯著降低H_2O_2引起的EC-PMN粘附。
- This paper reviews the methods that analyze the positional distribution of fatty acids in triacylglycerol, such as the methods of specific lipase, phospholipase A2, derivatization reagent, HPLC, etc. 綜述了甘油三酯中不同位置上醯化脂肪酸的組成及含量的幾種測定方法,如專一性脂肪酶法、磷脂酶A2法、衍生化試劑法、HPLC法等。
- This paper reviews the methods that analyze the positional distribution of fatty acids in triacylglycerol,such as the methods of specific lipase,phospholipase A2,derivatization reagent,HPLC,etc. 綜述了甘油三酯中不同位置上醯化脂肪酸的組成及含量的幾種測定方法,如專一性脂肪酶法、磷脂酶A2法、衍生化試劑法、HPLC法等。
- This thesis presents the role of drugs on activity of phospholipase A2 in the model bile was studied and important information for cholelithiasis in clinical treatment was exhibited. 因此,我們在模型膽汁中研究藥物對磷脂酶A2的作用,可為臨床治療膽石病提供重要信息。