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- The gene silence of XAF1 is related with the hypermethylation of its promotor. XAF1的基因沉默與其啟動子高甲基化明顯相關。
- The mechanisms of gene silencing include copy numbers and configuration of transgene, integration sites in plant and transcription of transgene, etc. 基因沉默的機制是多方面的,包括轉基因的拷貝數和構型、在植物上的整合位點、轉基因的轉錄水平等。
- Abstract: BACKGROUND: Gene promoter methylation is an epigenetic eent leading to gene silencing. 摘要:背景:基因啟動子甲基化是一種可引起基因沉默的表觀遺傳事件。
- Gene silencing can be divided into two types: position effect and homology dependent gene silencing (HdGS). 基因沉默大體可以分為兩類:位置效應引起的基因沉默和同源依賴的基因沉默。
- Gene silencing is a kind of epigenetic phenomenon discovered in transgenic plants in recent years. 摘要基因沉默是近幾年來在轉基因植物中發現的一種後生遺傳現象。
- Finally, the researchers showed that DNMT1-stimulated HP1 binding is required for gene silencing. 最後,研究者指出DNMT1激發性Hp1蛋白的結合作用需要基因沉默。
- Posttranscriptional gene silencing(PTGS) is considered to be one of dominant mechanisms of RNA-mediated resistance. 轉錄后基因沉默現象是植物抵禦病毒入侵、保持自身基因組完整性的一種防禦機制。
- RNA interference (RNAi) is a postranscriptional gene silencing (PTGS) mechanism induced by double-stranded RNA (dsRNA). 摘要RNA干擾,是1種由雙鏈RNA引發的轉錄后基因沉默現象。
- This mutant showed an increased sensitivity to DNA damage and release of transcriptional gene silencing (TGS) in heterochromatin. 這個突變體同時也顯現了對DNA損傷的高敏感性以及在異染色質上轉錄基因沉默(TGS)的釋放。
- Abstract:Objective:To observe the effect of PKB gene silencing on the growth of gastric cancer cell line SGC-7901 in vitro. 目的:探討蛋白激酶B(PKB)基因沉默對人胃癌SGC-7901細胞增殖的作用。
- Posttranscriptional gene silencing (PTGS) in plants is a form of RNA silencing by which target RNA is degraded in a sequence-specific manner. 植物中的轉錄后基因沉默(PTGS)是RNA沉默的一種形式,通過PTGS能對目標RNA進行特異性降解。
- From long period evolution with plants, plant virus obtains the ability to code gene silencing suppressors against this defense system. 基因沉默系統是植物抵抗病毒侵染的防衛體系,在長期的協同進化過程中,由病毒編碼的抑制蛋白可以抵消基因沉默系統的作用。
- TMV CP;different constructs;methylation;post transcriptional gene silencing;watermelon;virus diseases;transformation;resistance. 不同結構形式;甲基化;轉錄后基因沉默;西瓜病毒病;轉基因;抗病性
- EXPRESSION OF CATALASE GENE perA FROM BACILLUS STEAROTHERMOPHILUS IN RECOMBINANT E. COLI 嗜熱脂肪芽孢桿菌過氧化氫酶基因perA在大腸桿菌中的高效表達
- SET domain proteins of SUV3-9H family specifically methylate the residue lysine 9 of histone H3, resulting in gene silencing. Su(var)3-9家族的SDP專一甲基化組蛋白3第9位賴氨酸(H3K9),從而導致基因沉默(gene silencing)。
- Transgenic plants with high and stable expression are ideal to get by plant gene engineering, but gene silencing limits their application. 摘要植物基因工程研究是希望獲得高穩定表達的轉基因植株,而轉基因沉默現象卻限制了轉基因植物的應用前景。
- It degrades mRNA specifically and potently through the mediation of corresponding double-stranded RNA and leads to post-transcriptional gene silencing. 它通過雙鏈RNA的介導特異性地降解相應序列的mRNA,從而導致轉錄后水平的基因沉默。
- The results suggest that gene silencing may be "an efficient and more specific approach for therapy of liver fibrosis," the report states. 報告指出,得到的結果表明基因沉默可能是「一個有效的和更具體的治療肝纖維化的方法」。
- With the widely application of transgene technology in the fields of high level biologies, more and more attention was payed to gene silence. 隨著轉基因技術在高等生物中的廣泛應用,轉基因沉默受到越來越多的重視。
- These phenomena include gene silencing, DNA methylation, nucleolar dominance, transposable elements activation and genomic imprinting. 表觀遺傳變異包括基因沉默、DNA甲基化、核仁顯性、休眠轉座子激活和基因組印記等方面。