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- A method was developed for determination of adenylate cyclase(AC) and cAMP phosphodiesterase(PDE) specific activities by radioisotopic assay. 本文報道腺苷酸環化酶(AC)和環腺苷酸磷酸二酯酶(PDE)比活力的放射性同位素測定法。
- Effects of narcotics on adenyl cyclase and phosphodiesterase activity in rabbit bronchial smooth muscle. 常用麻醉性鎮痛葯對家兔支氣管平滑肌腺苷酸環化酶和磷酸二酯酶活力的影響
- Phosphodiesterase 8B gene variants are associated with serum TSH levels and thyroid function. 磷酸二酯酶8B基因變異體與血清TSH水平和甲狀腺功能有關。
- Many men in their reproductive years are now using phosphodiesterase type 5 inhibitors. 目前許多生育期男性在服用磷酸二酯酶5抑製劑。
- Inhibitor of cyclic adenosine 3』,5』-monophosphate phosphodiesterase and topoisomerase ITopo I). 抑制環腺苷3』,5』-一磷酸鹽磷酸二酯酶和拓撲酶I。
- I also use a medicine called Trental or Pentoxifylline as a phosphodiesterase inhibitor. 我也使用磷酸二酯酶抑製劑如巡能泰或己酮可可鹼進行治療。
- ED treatment has changed fundamentally since phosphodiesterase type 5 inhibitor(PDE5-I) came into clinizal use. 自從5型磷酸二酯酶抑製劑(PDE5-I)出現后,ED的治療發生了革命性的變化。
- Phosphodiesterase 3 inhibitor attenuates cough response in a sensitized guinea pig model. 中國病理生理雜誌，第二，2007年，in press。
- Attempts have been made to know the statws quo of the phosphodiesterase inhibitor clinical practice in recent years. 了解磷酸二酯酶抑製劑近年來的臨床應用情況,並對其作用機制進行分析,為進一步的開發應用提供依據。
- This same enzyme, phosphodiesterase type 5, also limits blood flow by contracting the muscles around blood vessels. 同一種酶，5型磷酸二酯酶也通過收縮血管壁平滑肌減少血流。
- PURPOSE: Phosphodiesterase type 5 inhibitors are the first choice therapy in the treatment of erectile dysfunction. 目的：磷酸二酯酶5抑製劑是治療勃起功能障礙的首選用藥。
- Benzylisoquinoline compounds antagonized calmodulin ( CaM ) to inhibit the activity of CaM-dependent cyclic nucleotide phosphodiesterase ( CaM-PDE ) . 苄基異喹啉類化合物拮抗鈣調素(CaM),對環核苷酸磷酸二酯酶(CaM-PDE)產生抑制作用。
- Sildenafil citrate is a phosphodiesterase type 5 (PDE5) inhibitor used clinically for the treatment of male erectile dysfunction. 枸櫞酸西地那非是磷酸二酯酶-5(PDE5)的抑製劑，臨床用來治療勃起機能障礙。
- And one of the things were looking at is specific phosphodiesterase inhibitors to block the endotoxin or LPS-stimulable TNF. 目前正在做的一項工作是用特異性磷酸二酯酶抑製劑來阻斷內毒素或LPS脂多糖刺激TNF的產生。
- Saleheen D,Bukhari S,Haider SR,et al.Association of phosphodiesterase 4D gene with ischemic stroke in a pakistani population[J].Stroke,2005,36:2275. 李才明;張成;張鴻煉;等.;磷酸二酯酶4D基因與缺血性腦卒中的遺傳易患性研究[J]
- The authors have done the research by consulting the relative domestic phosphodiesterase inhibitor literature published in recent years. 查閱近年來國內有關磷酸二酯酶抑製劑的文獻資料。
- Objective:To observe the effect of Guizhi Decoction (GZD) on adenyl cyclase (AC) and phosphodiesterase (PDE) activities in hypothalamus of rat models of fever and hypothermia. 目的 :觀察桂枝湯對發熱和低體溫模型大鼠下丘腦中腺苷酸環化酶 (AC)和磷酸二酯酶(PDE)活性的影響。
- Benzylisoquinoline compounds antagonize calmodulin (CaM) and inhibit the activity of cyclic nucleotide phosphodiesterase which is CaM-dependent (CaM-PDE) . 苄基異喹啉類化合物拮抗鈣調素(CaM)並抑制依賴CaM的環核苷酸磷酸二酯酶(CaM-PDE)的活力;
- Phosphodiesterase 4(PDE 4),which specifically decomposes cAMP,is mainly distributed in various inflammatory cells and promotes exacerbation of inflammation. 磷酸二酯酶 (PDE- 4 )主要分佈於各類炎性細胞 ,能專一性水解環腺苷酸 (c AMP) ,促進炎症的發展。
- The yeast Saccharomyces cerevisiae contains two genes, PDE1 and PDE2, whichencode a low-affinity and a high-affinity cAMP phosphodiesterase, respectively. 釀酒酵母本身具有兩個編碼環腺苷酸(cAMP)磷酸二酯酶的基因PDE1和PDE2。 它們分別編碼低親和力的cAMP磷酸二脂酶Pde1和高親和力的cAMP磷酸二脂酶Pde2。
