Vascular Endothelial Growth Factor and its receptors may be the pivotal stimulants in the process of growth and metastasis of a neoplasm. 血管內皮生長因子及其受體在腫瘤的生長和轉移過程中可能是最關鍵的刺激因子。
Beacizumab, a monoclonal antibody targeting ascular endothelial growth factor, is approed by the US Food and Drug Administration for metastatic colon cancer. 由美國食品與藥品管理局批准治療轉移克隆癌的貝伐單抗,是血管內皮生長因子的單克隆抗體。