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- To explore the intensity of inhibitory function of Shenkang injection (SKI), a Chinese herbal recipe, and benazepril on the proliferation of human glomerular mesangial cell (MC). 目的:探討腎康注射液與苯那普利對人腎小球系膜細胞(MC)增殖的不同抑制作用強度。
- Result Nicardipine can induce rat mesangial cell apoptosis in vivo. 結論尼卡地平在體內有誘導大鼠系膜細胞凋亡的作用。
- Objective:Quantitative analysis of expression of endothelin B receptor(ETB-R)gene in rat heart,liver,lung,kidney and cuItured glomerular mesangial cells(MC)were observed. 目的:定量檢測B型內皮素受體(ETB-R)基因在大鼠心、肝、肺、腎等器官及培養的腎小球系膜細胞(MC)的表達。
- The production and expression of IL-6 infetal mesangial cell (MC) 人胎腎小球系膜細胞產生與表達白介素-6
- Objective To study the effect of nicardipine on rat mesangial cell apoptosis in vivo. 目的探討尼卡地平體內對大鼠系膜細胞凋亡的誘導作用。
- Objective To observe the effects of high glucose on the production of tissue plasminogen activator (t PA) by human glomerular mesangial cells (MC), its binding ability to the cells, and the role of fibronectin (FN) in this event. 目的 觀察高糖狀態下系膜細胞與組織型纖溶酶原激活物 (Tissueplasminogen ,t PA)結合力及系膜細胞產生t PA活性改變與纖維連接蛋白 (Fibronectin ,FN)產生的影響。
- Mesangial cell nuclei showed irregular shape and mitochondria swelled, stroma was normal. 系膜細胞核不規則,胞質內線粒體腫脹.系膜基質正常。
- Objective To study the effect of L arginine/NOS pathway on LPS stimulated human renal mesangial cell proliferation. 目的:探討L精氨酸/一氧化氮合酶途徑在脂多糖(LPS)對人腎系膜細胞增殖中的作用。
- Endothelial and mesangial cells are normal in number. 內皮細胞和系膜細胞數目正常。
- We also studied the phenomenon of mesangial cell apoptosis by TUNEL and the expression of Bcl-2 and,Caspase-3 and Fas by immunohistochemistry SABC. TUNEL法檢測系膜區細胞凋亡現象; 免疫組化SABC法檢測Bcl-2、Caspase-3、Fas蛋白的表達情況。
- DCN-media ted transduction possibly by signaling molecule ERK1/2 and SAPK/JNK and p21 protein can suppress the cultured mesangial cell growth. DCN對腎MsC的生長有抑制作用,其機制可能經ERK1/2、SAPK/JNK和p21蛋白介導。
- Objective To study the effect of Shenshuning mixture on phenotypic modulation of mesangial cell in glomerulosclerosis rats and its mechanism. 目的觀察中成藥復方腎疏寧對腎小球硬化模型大鼠腎小球系膜細胞表型轉化的作用,探討腎疏寧防治腎小球硬化的作用機制。
- Conclusion Nicardipine can induce rat mesangial cell apoptosis in vivo, which may be a useful medicine in treating mesangial proliferative glomerulonephritis. 這可能是治療系膜增生性腎小球腎炎的有效藥物。
- Objective To explore the inhibitory effect of decorin(DCN) on rat mesangial cell (MsC) growth and on the expression of mitogen-activated protein kinases (MAPKs) and p21 protein. 目的探討飾膠蛋白聚糖(DCN)對大鼠系膜細胞(MsC)生長的抑制作用及其信號轉導分子MAPKs和p21表達的影響。
- The clear supernatant of rat macrophage cultivated in DMEM culture fluid containing 12.5 mol/L glucose could markedly promote the hyperplasia of mesangial cell(P<0.01). 大鼠巨噬細胞在含12.;5mol/L葡萄糖的DMEM培養液中培養24h;其上清明顯促進系膜細胞增殖的(P<0
- Objective To study the effects of acyl-coenzyme A cholesterol acyltransferase inhibitor(ACATI, 58-035) on cholesterol homeostasis in lipid-loaded human mesangial cell line(HMCL) . 摘要 目的 研究醯基輔酶A膽固醇醯基轉移酶抑製劑(ACATI,58-035)對脂質負荷人系膜細胞系(HMCL)細胞內脂質穩態的影響。
- Anti-mesiangial cell antibodies could directly interact with antigens located on mesangial cell membrane and form in situ immune complexes in renal mesangium. 結論 1.;部分抗腎小球系膜細胞抗體與抗DNA抗體無關,提示抗DNA抗體以外的直接針對腎小球系膜細胞的自身抗體可能在狼瘡腎炎的發病中起一定作用。
- The activation of PTK/transcription activator signaling cascades can stimulate the excessive proliferation of mesangial cell proliferation and then result in diabetic nephropathy. 蛋白酪氨酸激酶/轉錄激活子途徑信號級聯放大的激活刺激腎小球膜細胞過度增殖,導致糖尿病腎病。
- Moreover, mesangial cells possess phagocytosis, production of various bioactive substances and so on. 此外,系膜細胞還有吞噬及產生並分泌多種生物活性物質等功能。
- The normal mesangium contains about 2 to 4 mesangial cells, which have a macrophage-like function. 正常的腎小球膜包含大約2到4個腎小球細胞,有類似巨噬細胞的作用。