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- The ionotropic glutamate receptor antagonists D-AP5 and CNQX could not fully block the action of ACM. 離子型谷氨酸受體拮抗劑D-AP5和CNQX不能完全阻斷條件培養基的作用。
- DAO is expressed in the human brain, where it oxidizes D-serine, a potent activator of NMDA glutamate receptor. DAO表達在人的大腦中,它可以氧化D-絲氨酸,後者則是一個強力的NMDA谷氨酸受體激活劑。
- AIM To study the changes and effects of metabotropic glutamate receptor subtype 2 (mGluR2) in diffuse brain injuries (DBI) coupled with secondary brain insults (SBI) in rats. 目的 研究瀰漫性腦損傷 (diffusebraininjury;DBI)及其合併二次腦損傷 (secondarybraininsults;SBI)后大鼠腦皮層代謝性谷氨酸受體 2亞型 (mGluR2 )的變化及其意義 .
- AIM To study the changes and effects of metabotropic glutamate receptor subtype 4 (mGluR4) after diffuse brain injuries (DBI) coupled with secondary brain insults (SBI) in rats. 目的 研究瀰漫性腦損傷 (DBI)及其合併二次腦損傷 (SBI)后大鼠腦皮層代謝型谷氨酸受體亞型 4(m Glu R4)的變化及意義 .
- Howlett found the fruit fly's metabotropic glutamate receptor (DmGluRA) gene, when mutated, increased the excitability of the neuron by preventing PI3K from doing its job. 赫爾特發現當果蠅的親代謝性谷氨酸鹽受體基因發生突變時,將通過阻止PI3K的作用來增加神經元的興奮性。
- Tra2 is an SR-like protein that has several isoforms and, regulates the alternative pre-mRNA splicing of many important genes, including the glutamate receptor. Tra2(splicing factor Transformer-2)是一種SR相關蛋白的選擇性剪接因子,有多種亞型,Tra2參與包括谷氨酸受體在內的很多重要基因前體mRNA的選擇性剪接。
- During both in vivo and in vitro development, CGC depend on the activity of the NMDA glutamate receptor subtype for survival and full differentiation [3]. 在體內和體外發育過程中,小腦顆粒細胞依賴於N-甲基-D-天冬氨酸(NMDA)谷氨酸鹽受體亞型的活性而生存和完全分化。
- More precisely, they block the action of a form of glutamate receptor known as the NMDA receptor, which plays a critical role in brain development, learning, memory and neural processing in general. 說得更精確些,這些藥物阻斷了一種叫做NMDA型的麩胺酸受體,該受體對於大腦的發育、習、憶以及一般的神經活動都扮演著舉足輕重的角色。
- The N-methyl-D-aspartate receptor (NR), a subtype of ion-tropic glutamate receptor, provides sites for phosphorylation and for channel blocking. NRs are composed of NR1 and NR2A-D subunits. 現已發現NMDAR至少存在7個亞單位,即NR1亞單位、4種NR2亞單位(分為NR2A、NR2B、NR2C和NR2D)以及2種NR3亞單位。
- Further pharmacological experiments revealed that S100B secretion was critically dependent on presynaptic release of neurotransmitter and activation of metabotropic glutamate receptor 3. 進一步喲來實驗揭示了S100B釋放是一種突觸前神經遞質釋放的方式,並且依賴於代謝型谷氨酸受體3的激活。
- Glutamate receptors are divided into two subtypes,i.e.,ionotropic glutamate receptor(iGluR)and metabotropic glutamate receptor(mGluR). 谷氨酸是中樞神經系統最主要的興奮性神經遞質,其受體共分為兩大類:離子型及代謝型,兩者均廣泛分佈於中樞神經系統。
- The glutamate receptor interacting protein 1 (GRIP1) is a scaffolding protein in postsynaptic density (PSD), tethering AMPA receptors to other signaling proteins. GRIP1可以直接與AMPA受體相互作用並將之與其它信號蛋白聯結在一起。
- Glutamate receptors can be divided into two major classes: AMPA and NMDA receptors. 谷氨酸受體主要可以分為兩大類:AMPA受體和NMDA受體。
- There are two classes of glutamate receptors: ionotropic(iGluRs) and metabotropic(mGluRs). 谷氨酸受體有促離子型受體和促代謝型受體兩種類型。
- lonotropic glutamate receptor (iGluR) 親離子型谷氨酸受體
- Glutamate is a primary excitatory neurotransmitter and responsible for mediating a broad range of nervous system functions through glutamate receptors. 目的谷氨酸是一種重要的興奮性神經遞質,通過體內的谷氨酸受體參與神經系統多種功能的調節。
- metabotropic glutamate receptor 5 代謝型谷氨酸受體5型
- Agents that directly activate 「AMPA-type」 glutamate receptors, which work in concert with NMDA receptors, are also under active investigation. 另外有一種稱為AMPA型的麩胺酸受體,可與NMDA受體攜手合作;直接刺激AMPA受體的藥劑,目前也正積極研究當中。
- For the past year, I have been working with a subset of neuronal glutamate receptors via voltage clamping on Xenopus oocytes. 過去的一年裡,我一直在研究在蛙卵上神經元谷氨酸受體的一個子集通過電壓箝位的現象。
- metabotropic glutamate receptor 7 subtype 代謝型谷氨酸受體7亞型