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- Conclusion Memantine will affect liver and brain of neonatal rats. 結論美金胺對新生大鼠的腦和肝臟影響較大。
- Of the 44 patients, 50% also received adjunctive therapy with memantine. 其中50%25也接受美金剛的輔助治療。
- The researchers also found that memantine was able to dampen brain activity in some affected areas and reduce pain accordingly. 研究人員也發現美金剛胺能夠抑制腦中受侵襲部位的活動從而減少疼痛。
- The pathologic changes and mortality rate of neonatal rats were positively correlated with the dosage of memantine. 新生大鼠的病理變化程度及死亡率與美金胺的劑量呈正相關。
- To test this idea, she asked a number of patients undergoing amputation to take a drug called memantine. 為了檢驗這個想法，她讓進行截肢的病人服用一種叫美金剛胺(Memantine)的藥物。
- This paper introduces mechanism of action,pharmacokinetics and determination of Memantine. 現綜述其作用機制、體內過程與測定技術。
- Thirteen patients took memantine for four weeks after their amputations (and sometimes just before, as well). 13名病人在他們截肢之後（有些病人也在截肢前）服用美金剛胺持續4個星期。
- Memantine,a low-to moderate-affinity,uncompetive NMDA receptor antagonist,was approved for treatment of moderate to severe Alzheimer's disease. 美金剛是一種低中度親和力、非競爭性NMDA受體拮抗劑,已被批准用於治療中、重度阿爾茨海默氏病。
- Memantine hydrochloride was synthesized from 1,3 dimethyladamantane by bromination, acetamidation with acetonitrile in sulfuric acid and hydrolysis with an overall yield of 67.8%. 以1;3-二甲基金剛烷為原料;經溴化、乙腈和硫酸的作用下乙醯胺基化、水解、成鹽等反應及改進的后處理方法得到鹽酸美金剛;總收率67.;8%25。
- Memantine Hydrochloride is developed by German and comes into market, in China, which belongs to new drug of third classification at the phase of development. 鹽酸美金剛由德國研製上市，國內處於新葯研發階段，屬國家三類新葯。
- To their delight, they discovered that memantine not only reduced changes in the brain, it also decreased both the incidence and the intensity of phantom pain. 讓他們欣慰的是，他們發現美金剛胺不但減少了大腦的改變，而且也降低了患肢疼痛的次數和強度。
- The synthesis, properties and application of N,N - Dimethyl Acrylamide( DMAA) are introduced. The DMAA is a fine chemical raw material and has a bright developing and using future. 介紹了N,N-二甲基丙烯醯胺(DMAA)的合成、性能及其應用情況,認為N,N-二甲基丙烯醯胺是一種具有廣泛開發應用前景的精細化工原料。
- Memantine has been prescribed for more than 20 years for various brain disorders, including dementia, because it is believed to protect against high levels of a neurotransmitter called glutamate. 美金剛胺已經被開給各種腦疾病的病人超過20年了，這些病人包括痴呆症患者。因為人們相信美金剛胺可以保護人腦免受過量的谷氨酸鹽（一種神經遞質）的損害。
- The project is of anti-risk ability, after the construction, the new formulations of Memantine Hydrochloride can be developed according to the markets, so which is better economic and social benefit. 該項目抗風險能力很強，項目建成后，可滿足後續開發鹽酸美金剛新劑型的需要，具有較好的經濟效益和社會效益。
- Keywords cationic polymer;DMAA;ammonium salt; 陽離子聚合物;二甲基烯丙基胺;銨鹽;
- Keywords Omethoate;Memantine;Experimental therapy; 氧樂果;美金剛;實驗治療;
- Keywords Memantine;Hypoxic-ischemic brain damage;Rats;newborn; 美金胺;缺氧缺血性腦損傷;新生大鼠;
- Keywords memantine;HSP70 gene;hypoxic ischemia;neonatal rat; 關鍵詞美金胺;熱休克蛋白70基因;缺氧缺血;新生大鼠;
- Keywords memantine hydrochloride alzheimer agent synthesis; 鹽酸美金剛胺;痴呆症治療藥物;合成;
- Keywords memantine neonatal rats repeat dose toxicity; 美金胺新生大鼠重複用藥毒性;
